amitriptyline has been researched along with Psychomotor Agitation in 15 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Psychomotor Agitation: A feeling of restlessness associated with increased motor activity. This may occur as a manifestation of nervous system drug toxicity or other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Dosage was increased stepwise from 100mg up to 400mg trimipramine and from 100mg up to 200mg amitriptyline combined with 2mg up to 7." | 2.74 | Outcome in delusional depression comparing trimipramine monotherapy with a combination of amitriptyline and haloperidol--a double-blind multicenter trial. ( Ackl, N; Hatzinger, M; Held, K; Holsboer, F; Holsboer-Trachsler, E; Ising, M; Kaschka, W; Kasper, S; Konstantinidis, A; Künzel, HE; Sonntag, A; Steiger, A; Uhr, M; Yassouridis, A, 2009) |
| "Mirtazapine-treated patients demonstrated a statistically significant (p < or = ." | 2.40 | A meta-analysis of eight randomized, double-blind, controlled clinical trials of mirtazapine for the treatment of patients with major depression and symptoms of anxiety. ( Barkin, RL; Fawcett, J, 1998) |
| "touching her stool) though neuroleptic malignant syndrome subsided." | 1.30 | [A case of depression manifesting incessant pacing and wandering following discontinuation of antipsychotic drugs due to neuroleptic malignant syndrome: a possible involvement of withdrawal akathisia]. ( Terao, T; Watanabe, H, 1997) |
| "Haloperidol was implicated in 47 patients (37%), followed by amitriptyline/perphenazine in 30%, thioridazine in 27%, and chlorpromazine in 20%." | 1.28 | Neurologic approach to drug-induced movement disorders: a study of 125 patients. ( Jankovic, J; Miller, LG, 1990) |
| "Some types of bipolar depression may be considered as atypical if accompanied by reversed vegetative change." | 1.26 | Atypical depression. ( Davidson, JR; Miller, RD; Sullivan, JL; Turnbull, CD, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (53.33) | 18.7374 |
| 1990's | 6 (40.00) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Künzel, HE | 1 |
| Ackl, N | 1 |
| Hatzinger, M | 1 |
| Held, K | 1 |
| Holsboer-Trachsler, E | 1 |
| Ising, M | 1 |
| Kaschka, W | 1 |
| Kasper, S | 1 |
| Konstantinidis, A | 1 |
| Sonntag, A | 1 |
| Uhr, M | 1 |
| Yassouridis, A | 1 |
| Holsboer, F | 1 |
| Steiger, A | 1 |
| GREENFIELD, AR | 2 |
| Davidson, JR | 1 |
| Miller, RD | 1 |
| Turnbull, CD | 1 |
| Sullivan, JL | 1 |
| Delini-Stula, A | 1 |
| Mikkelsen, H | 1 |
| Angst, J | 1 |
| Watanabe, H | 1 |
| Terao, T | 1 |
| Fawcett, J | 1 |
| Barkin, RL | 1 |
| Kugaya, A | 1 |
| Akechi, T | 1 |
| Nakano, T | 1 |
| Okamura, H | 1 |
| Shima, Y | 1 |
| Uchitomi, Y | 1 |
| Strian, F | 1 |
| Albert, W | 1 |
| Klicpera, C | 1 |
| Langee, HR | 1 |
| Conlon, M | 1 |
| Miller, LG | 1 |
| Jankovic, J | 1 |
| Jackson, RD | 3 |
| Mysiw, WJ | 2 |
| Danel, T | 1 |
| Servant, D | 1 |
| Goudemand, M | 1 |
| Corrigan, JD | 2 |
| Arnett, JA | 1 |
2 reviews available for amitriptyline and Psychomotor Agitation
| Article | Year |
|---|---|
Therapeutic efficacy of antidepressants in agitated anxious depression--a meta-analysis of moclobemide studies.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Anxiety Disorders; Benzamides; Clinical Trials as | 1995 |
A meta-analysis of eight randomized, double-blind, controlled clinical trials of mirtazapine for the treatment of patients with major depression and symptoms of anxiety.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amitriptyline; Antidepressive Agents, Tricyclic; Depress | 1998 |
2 trials available for amitriptyline and Psychomotor Agitation
| Article | Year |
|---|---|
Outcome in delusional depression comparing trimipramine monotherapy with a combination of amitriptyline and haloperidol--a double-blind multicenter trial.
Topics: Adrenocorticotropic Hormone; Adult; Amitriptyline; Anti-Dyskinesia Agents; Antidepressive Agents, Tr | 2009 |
Abnormal cortisol dynamics after traumatic brain injury. Lack of utility in predicting agitation or therapeutic response to tricyclic antidepressants.
Topics: Adolescent; Adult; Amitriptyline; Arousal; Brain Injuries; Clinical Trials as Topic; Desipramine; De | 1989 |
11 other studies available for amitriptyline and Psychomotor Agitation
| Article | Year |
|---|---|
Control of alcoholic agitation and depression with perphenazine and amitriptyline combined.
Topics: Alcoholism; Amitriptyline; Antidepressive Agents; Depression; Depressive Disorder; Humans; Perphenaz | 1963 |
CONTROL OF ALCOHOLIC AGITATION AND DEPRESSION.
Topics: Alcoholism; Amitriptyline; Anxiety; Anxiety Disorders; Depression; Depressive Disorder; Humans; Perp | 1963 |
Atypical depression.
Topics: Adult; Age Factors; Amitriptyline; Anxiety; Bipolar Disorder; Depressive Disorder; Double-Blind Meth | 1982 |
[A case of depression manifesting incessant pacing and wandering following discontinuation of antipsychotic drugs due to neuroleptic malignant syndrome: a possible involvement of withdrawal akathisia].
Topics: Adult; Akathisia, Drug-Induced; Amitriptyline; Depression; Female; Humans; Methotrimeprazine; Neurol | 1997 |
Successful antidepressant treatment for five terminally ill cancer patients with major depression, suicidal ideation and a desire for death.
Topics: Affect; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Attitude to Death; Clomipramine; Cogn | 1999 |
Course of depressive mood and psychomotor activation in endogenous depression.
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Depression; Electroconvuls | 1979 |
Predictors of response to antidepressant medications.
Topics: Aggression; Amitriptyline; Antidepressive Agents; Depression; Doxepin; Follow-Up Studies; Humans; In | 1992 |
Neurologic approach to drug-induced movement disorders: a study of 125 patients.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Amitriptyline; Antipsychotic Agents; Chorea | 1990 |
Amitriptyline in the treatment of neuroleptic-induced akathisia.
Topics: Adult; Akathisia, Drug-Induced; Amitriptyline; Antipsychotic Agents; Female; Humans; Psychomotor Agi | 1988 |
Amitriptyline for post-traumatic agitation.
Topics: Adolescent; Adult; Amitriptyline; Amnesia; Brain Injuries; Cognition; Female; Humans; Male; Middle A | 1988 |
Amitriptyline for agitation in head injury.
Topics: Adult; Aggression; Amitriptyline; Brain Injuries; Female; Humans; Psychomotor Agitation | 1985 |