Page last updated: 2024-10-22

amitriptyline and Poisoning

amitriptyline has been researched along with Poisoning in 84 studies

Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.

Poisoning: Used with drugs, chemicals, and industrial materials for human or animal poisoning, acute or chronic, whether the poisoning is accidental, occupational, suicidal, by medication error, or by environmental exposure.

Research Excerpts

ExcerptRelevanceReference
"We describe a case of tricyclic antidepressant poisoning where significant clinical toxicity (QRS prolongation, metabolic acidosis) was observed for up to 4 days following ingestion of a modified-release preparation of amitriptyline."7.73Prolonged clinical effects in modified-release amitriptyline poisoning. ( Dargan, P; Greene, S; Jones, A; O'Connor, N; Wyncoll, D, 2006)
"To compare the characteristics of dextropropoxyphene (DXP) poisoning victims with those of victims of poisonings by antidepressants and sedatives, we examined all fatal poisonings due to DXP, antidepressants or sedatives among autopsies performed at one department of forensic medicine in Sweden during the six-year period from 1992 to 1997."7.70Among fatal poisonings dextropropoxyphene predominates in younger people, antidepressants in the middle aged and sedatives in the elderly. ( Jonasson, B; Jonasson, U; Saldeen, T, 2000)
" The aim of this study was to compare the effects of several inotropic drugs on survival and the occurrence of arrhythmias in the treatment of amitriptyline poisoning."7.69Effects of epinephrine, norepinephrine, magnesium sulfate, and milrinone on survival and the occurrence of arrhythmias in amitriptyline poisoning in the rat. ( Abrahamsson, J; Knudsen, K, 1994)
"To compare cardiopulmonary bypass (CPB) with more conventional therapy in the treatment of severe amitriptyline poisoning."7.69Experimental amitriptyline poisoning: treatment of severe cardiovascular toxicity with cardiopulmonary bypass. ( Graeber, GM; Hollingsed, MJ; Larkin, GL, 1994)
"20 cases of amitriptyline poisoning have been reported."7.68[Analysis of 20 cases of amitriptyline poisoning]. ( Zhang, X; Zhu, Y, 1992)
"Amitriptyline is a very frequently prescribed antidepressant agent and is very often involved in attempted suicides."5.35A case report of amitriptyline poisoning successfully treated with the application of plasma exchange. ( Akman, A; Belen, B; Dilsiz, G; Olguntürk, R; Yenicesu, I; Yüksel, N, 2009)
"However, ventricular tachycardia was detected which did not respond to lidocaine, bicarbonate and cardioversion treatment."5.31Efficacy of long duration resuscitation and magnesium sulphate treatment in amitriptyline poisoning. ( Citak, A; Karaböcüoğlu, M; Soysal, DD; Uçsel, R; Uzel, N, 2002)
" Paracetamol, amitriptyline, chlorpromazine, ferrous sulphate, kerosene, organophosphates, carbon monoxide, snake bite, alcohol and rodenticides were involved in the poisoning."3.91Childhood Drug and Non-Drug Poisoning in Nigeria: An Economic Appraisal. ( Chijioke-Nwauche, I; Ikhile, I; Orisakwe, OE, 2019)
"A comparative study of the use of specific antidepressants (amitriptyline and dosulepin (tricyclics), citalopram, fluoxetine, paroxetine and sertraline (selective serotonin reuptake inhibitors) and venlafaxine (serotonin norepinephrine reuptake inhibitor)) for non-fatal self-poisoning (episode-based), relative to prescribing, in three centres in England, 2004 to 2006."3.76A comparative study of non-fatal self-poisoning with antidepressants relative to prescribing in three centres in England. ( Bergen, H; Cooper, J; Hawton, K; Kapur, N; Murphy, E; Stalker, C; Waters, K, 2010)
"Pretreatment with amiodarone does not appear to significantly alter the lethality of amitriptyline poisoning in mice."3.73Amiodarone fails to improve survival in amitriptyline-poisoned mice. ( Barrueto, F; Chuang, A; Cotter, BW; Hoffman, RS; Nelson, LS, 2005)
"We describe a case of tricyclic antidepressant poisoning where significant clinical toxicity (QRS prolongation, metabolic acidosis) was observed for up to 4 days following ingestion of a modified-release preparation of amitriptyline."3.73Prolonged clinical effects in modified-release amitriptyline poisoning. ( Dargan, P; Greene, S; Jones, A; O'Connor, N; Wyncoll, D, 2006)
"To compare the characteristics of dextropropoxyphene (DXP) poisoning victims with those of victims of poisonings by antidepressants and sedatives, we examined all fatal poisonings due to DXP, antidepressants or sedatives among autopsies performed at one department of forensic medicine in Sweden during the six-year period from 1992 to 1997."3.70Among fatal poisonings dextropropoxyphene predominates in younger people, antidepressants in the middle aged and sedatives in the elderly. ( Jonasson, B; Jonasson, U; Saldeen, T, 2000)
" The aim of this study was to compare the effects of several inotropic drugs on survival and the occurrence of arrhythmias in the treatment of amitriptyline poisoning."3.69Effects of epinephrine, norepinephrine, magnesium sulfate, and milrinone on survival and the occurrence of arrhythmias in amitriptyline poisoning in the rat. ( Abrahamsson, J; Knudsen, K, 1994)
"20 cases of amitriptyline poisoning have been reported."3.68[Analysis of 20 cases of amitriptyline poisoning]. ( Zhang, X; Zhu, Y, 1992)
"Severe cardiovascular arrhythmias occurred in both groups with 3 in the CAC-HP group versus 1 incident with premature death in the CG."2.87Advanced Electrocardiogram Analysis in the Amitriptyline-poisoned Pig Treated with Activated Charcoal Haemoperfusion. ( Belhage, B; Dalhoff, K; Eriksen, T; Haarmark, C; Hoegberg, LCG; Jansen, T, 2018)
" IFE therapy is being recommended by US PCCs; protocols and dosing regimens are nearly uniform."1.39Lipid rescue 911: Are poison centers recommending intravenous fat emulsion therapy for severe poisoning? ( Christian, MR; Mycyk, MB; Pallasch, EM; Wahl, M, 2013)
"Amitriptyline was the most frequent agent followed by Nortriptyline."1.37Tricyclic antidepressants intoxication in Tehran, Iran: epidemiology and associated factors. ( Dianat, S; Hassanian-Moghaddam, H; Rahimian, R; Rashidi-Ranjbar, N; Rasouli, MR; Zarei, MR, 2011)
"She was in comatose, had generalized tonic clonic seizure, ventricular tachycardia, and wide QRS complexes."1.35Treatment of severe amitriptyline intoxication with plasmapheresis. ( Akyüz, M; Aydemir, C; Cabuk, H; Eldes, N; Kolsal, E; Numanoglu, V; Piskin, E; Tekin, IO, 2009)
"7 mg/kg per dose) (the drug dosage was not known in 13 children)."1.33Acute amitriptyline intoxication: an analysis of 44 children. ( Akbayram, S; Akgün, C; Caksen, H; Erol, M; Odabaş, D; Ozbek, H; Tuncer, O; Yilmaz, C, 2006)
"However, ventricular tachycardia was detected which did not respond to lidocaine, bicarbonate and cardioversion treatment."1.31Efficacy of long duration resuscitation and magnesium sulphate treatment in amitriptyline poisoning. ( Citak, A; Karaböcüoğlu, M; Soysal, DD; Uçsel, R; Uzel, N, 2002)
"Nortriptyline was not detected in most cases, suggesting that it may degrade more rapidly than desipramine."1.29The study of tricyclic antidepressants in formalin-fixed human liver and formalin solutions. ( Wahba, WW; Winek, CL; Zaveri, NR, 1993)
"The causes of sudden cardiac arrest (SCA) and its associated early death were examined in 179 patients with acute intoxications due to amitriptyline, antiarrhythmic agents and cardiac glycosides."1.28[Acute heart failure and its treatment in cardiologic drug poisoning]. ( Savina, AS, 1992)
" The effect of administering activated charcoal at varying intervals after dosing on the blood drug-level profiles of paracetamol and amylobarbitone was assessed by comparison with the profiles obtained when charcoal therapy was withheld."1.25Studies with activated charcoal in the treatment of drug overdosage using the pig as an animal model. ( Lipscomb, DJ; Widdop, B, 1975)

Research

Studies (84)

TimeframeStudies, this research(%)All Research%
pre-199050 (59.52)18.7374
1990's11 (13.10)18.2507
2000's14 (16.67)29.6817
2010's8 (9.52)24.3611
2020's1 (1.19)2.80

Authors

AuthorsStudies
Wu, PF1
Zhou, TY1
Zhang, JS1
Jansen, T1
Hoegberg, LCG1
Eriksen, T1
Haarmark, C1
Dalhoff, K1
Belhage, B1
Ikhile, I1
Chijioke-Nwauche, I1
Orisakwe, OE1
Christian, MR1
Pallasch, EM1
Wahl, M1
Mycyk, MB1
Kolsal, E1
Tekin, IO1
Piskin, E1
Aydemir, C1
Akyüz, M1
Cabuk, H1
Eldes, N1
Numanoglu, V1
Belen, B1
Akman, A1
Yüksel, N1
Dilsiz, G1
Yenicesu, I1
Olguntürk, R1
Anand, JS1
Habrat, B1
Sut, M1
Korolkiewicz, R1
Bergen, H1
Murphy, E1
Cooper, J1
Kapur, N1
Stalker, C1
Waters, K1
Hawton, K1
Dianat, S1
Zarei, MR1
Hassanian-Moghaddam, H1
Rashidi-Ranjbar, N1
Rahimian, R1
Rasouli, MR1
Oransay, K1
Kalkan, S1
Hocaoglu, N1
Arici, A1
Tuncok, Y1
Gaillard, Y1
Breuil, R1
Doche, C1
Romeuf, L1
Lemeur, C1
Prevosto, JM1
Fanton, L1
Lak, NS1
Malingre, MM1
Hogeman, PH1
Nenov, VD1
Marinov, P1
Sabeva, J1
Nenov, DS1
FENDRICK, GM1
SUNSHINE, P1
YAFFE, SJ1
KOLLBERG, H1
SORENSEN, NS1
ANDREASSEN, J1
SCHAERER, K1
KRUEGER, H1
ZUMPE, V1
EHRLY, AM1
BEYER, E1
STARK, JE1
BETHUNE, DW1
LISSAC, J1
SAVIER, CH1
DUREPAIRE, H1
AUZEPY, P1
BROCARD, H1
GOULDING, R1
BAEUMLER, J1
IMOBERSTEG, J1
Kazlauskiene, D2
Vainauskas, P2
Rakauskaite, D1
Marksiene, R1
Kiliuviene, G1
Barrueto, F1
Chuang, A1
Cotter, BW1
Hoffman, RS1
Nelson, LS1
Koski, A1
Vuori, E1
Ojanperä, I1
Ostapenko, YN1
Lisovik, ZA1
Belova, MV1
Luzhnikov, EA1
Livanov, AS1
O'Connor, N1
Greene, S1
Dargan, P1
Wyncoll, D1
Jones, A1
Caksen, H1
Akbayram, S1
Odabaş, D1
Ozbek, H1
Erol, M1
Akgün, C1
Tuncer, O1
Yilmaz, C1
Bek, K1
Ozkaya, O1
Mutlu, B1
Dağdemir, A1
Sungur, M1
Açikgöz, Y1
Işlek, I1
Baysal, K1
Steel, CM1
O'Duffy, J1
Brown, SS1
Hildebrandt, J1
Lauschke, G1
Sinkwitz, KD1
Schmidt, J1
Comstock, EG1
Faulkner, TP1
Boisaubin, EV1
Oslon, DA1
Comstock, BS1
Knudsen, K2
Abrahamsson, J2
Larkin, GL1
Graeber, GM1
Hollingsed, MJ1
Winek, CL1
Zaveri, NR1
Wahba, WW1
Kunst, I1
Balatka, J1
Fixa, P1
Pellarová, V1
Landová, M1
Winrow, AP1
Jonasson, B1
Jonasson, U1
Saldeen, T1
Citak, A1
Soysal, DD1
Uçsel, R1
Karaböcüoğlu, M1
Uzel, N1
Sharman, JR1
Cretney, MJ1
Scott, RD1
Janus, ED1
Bickel, MH1
Reed, S1
Schwartz, KM1
Jørgensen, KA1
Christensen, KN1
Pedersen, RS1
Klitgaard, NA1
Tilz, GP1
Teubl, I1
Kopplhuber, C1
Vollmann, H1
Lanzer, G1
Carpenter, DC1
Beaubien, AR1
Mathieu, LF1
Hrdina, PD1
Ballin, JC1
Lipscomb, DJ1
Widdop, B1
Raymond, CW1
Savina, AS1
Hilberg, T1
Bugge, A1
Beylich, KM1
Mørland, J1
Bjørneboe, A1
Zhu, Y1
Zhang, X1
Vergara Chozas, JM1
Márquez del Cid, J1
Crespo, S1
Meca Rovayo, ML1
Vernon, DD1
Banner, W1
Garrett, JS1
Dean, JM1
Lanquetot, H1
Furet, Y1
Kerourédan, V1
Poitrineau, O1
Hubiche, M1
Autret, E1
Wright, N1
Gupta, RN1
Smolle, KH1
Holzer, H1
Hedges, JR1
Otten, EJ1
Schroeder, TJ1
Tasset, JJ1
Rumack, BH1
Borden, EC1
Rostand, SG1
Berry, WK1
Davies, DR1
Gordon, JJ1
Christensen, H1
Winter, M1
Taylor, DJ1
Baber, WS1
Lindsay, JS1
Pollard, DE1
Ciocatto, E1
Fagiano, G1
Bava, GL1
Mellerio, F1
Gaultier, M1
Fournier, E1
Gervais, P1
Frejaville, JP1
Gard, H1
Knapp, D1
Hanenson, I1
Walle, T1
Gaffney, T1
Postlethwaite, RJ1
Price, DA1
Asbach, HW1
Schuler, HW1
Matthew, H1
Hulting, J1
Thorstrand, C1
Trautmann, A1
Breyer, U1
Remmer, H1
Bain, DJ1
Turner, T1
Zigo, I1
Kurpes, Z1
Panjan, I1
Bossaert, L1
Vermeire, P1
van Durme, JP1
Pannier, R1
Slovis, TL1
Ott, JE1
Teitebaum, DT1
Lipscomb, W1
Bwibo, NO1
Osnes, M1
Aardal, NP1
Sagardiluz, J1
Clèdes, J1
Potaux, L1
Favarel-Garrigues, JC1

Reviews

2 reviews available for amitriptyline and Poisoning

ArticleYear
Current applications of plasmapheresis in clinical toxicology.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2003, Volume: 18 Suppl 5

    Topics: Amitriptyline; Female; Humans; Male; Mushroom Poisoning; Paraquat; Plasmapheresis; Poisoning; Risk A

2003
Poisoning by tricyclic antidepressant drugs: general and pharmacokinetic considerations.
    International journal of clinical pharmacology and biopharmacy, 1975, Volume: 11, Issue:2

    Topics: Accidents, Home; Adolescent; Adult; Aged; Amitriptyline; Animals; Antidepressive Agents; Antidepress

1975

Trials

1 trial available for amitriptyline and Poisoning

ArticleYear
Advanced Electrocardiogram Analysis in the Amitriptyline-poisoned Pig Treated with Activated Charcoal Haemoperfusion.
    Basic & clinical pharmacology & toxicology, 2018, Volume: 122, Issue:4

    Topics: Administration, Oral; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac

2018

Other Studies

81 other studies available for amitriptyline and Poisoning

ArticleYear
Severe amitriptyline poisoning treated successfully with combined hemoperfusion and hemodialysis.
    Revista da Associacao Medica Brasileira (1992), 2020, Volume: 66, Issue:3

    Topics: Adolescent; Amitriptyline; Antidepressive Agents; Hemoperfusion; Humans; Male; Poisoning; Renal Dial

2020
Childhood Drug and Non-Drug Poisoning in Nigeria: An Economic Appraisal.
    Annals of global health, 2019, 07-09, Volume: 85, Issue:1

    Topics: Acetaminophen; Adolescent; Age Distribution; Amitriptyline; Analgesics, Non-Narcotic; Antipsychotic

2019
Lipid rescue 911: Are poison centers recommending intravenous fat emulsion therapy for severe poisoning?
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2013, Volume: 9, Issue:3

    Topics: Acute Disease; Adult; Amitriptyline; Bupivacaine; Drug Overdose; Fat Emulsions, Intravenous; Guideli

2013
Treatment of severe amitriptyline intoxication with plasmapheresis.
    Journal of clinical apheresis, 2009, Volume: 24, Issue:1

    Topics: Amitriptyline; Child, Preschool; Coma; Drug Overdose; Female; Humans; Plasmapheresis; Poisoning; Sei

2009
A case report of amitriptyline poisoning successfully treated with the application of plasma exchange.
    Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy, 2009, Volume: 13, Issue:2

    Topics: Adolescent; Amitriptyline; Antidepressive Agents, Tricyclic; Female; Humans; Plasma Exchange; Poison

2009
[Misuse of substances theoretically without abuse potential--case series].
    Przeglad lekarski, 2009, Volume: 66, Issue:6

    Topics: Amitriptyline; Analgesics; Anti-Inflammatory Agents; Antidepressive Agents; Baclofen; Benzydamine; C

2009
A comparative study of non-fatal self-poisoning with antidepressants relative to prescribing in three centres in England.
    Journal of affective disorders, 2010, Volume: 123, Issue:1-3

    Topics: Amitriptyline; Antidepressive Agents; Cross-Sectional Studies; Cyclohexanols; Dothiepin; England; Gu

2010
Tricyclic antidepressants intoxication in Tehran, Iran: epidemiology and associated factors.
    Human & experimental toxicology, 2011, Volume: 30, Issue:4

    Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Cross-Sectional Studies; Drug Overdose; Fema

2011
An alternative antidote therapy in amitriptyline-induced rat toxicity model: theophylline.
    Drug and chemical toxicology, 2011, Volume: 34, Issue:1

    Topics: Amitriptyline; Animals; Antidotes; Blood Gas Analysis; Blood Pressure; Carbon Dioxide; Disease Model

2011
Detection of amitriptyline, nortriptyline and bromazepam in liver, CSF and hair in the homicidal poisoning of a one-month-old girl autopsied 8 months after death.
    Forensic science international, 2011, Apr-15, Volume: 207, Issue:1-3

    Topics: Amitriptyline; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Bromazepam; Chromatography, Li

2011
Amitriptyline cream ingestion in a 1-year-old boy.
    Pediatrics, 2012, Volume: 130, Issue:4

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Humans; Infant; Male; Poisoni

2012
Amitriptyline poisoning.
    The New England journal of medicine, 1962, Nov-15, Volume: 267

    Topics: Amitriptyline; Antidepressive Agents; Humans; Poisoning

1962
AMITRIPTYLINE POISONING. CLINICAL AND PATHOLOGICAL FINDINGS IN A FATAL CASE.
    American journal of diseases of children (1960), 1963, Volume: 106

    Topics: Amitriptyline; Amobarbital; Antidepressive Agents; Apnea; Arrhythmias, Cardiac; Coma; Dialysis; Flui

1963
[ACUTE AMITRIPTYLINE POISONING].
    Svenska lakartidningen, 1964, Nov-18, Volume: 61

    Topics: Amitriptyline; Antidepressive Agents; Depression; Depressive Disorder; Hypotension; Poisoning; Toxic

1964
[AMITRIPTYLINE POISONING].
    Ugeskrift for laeger, 1964, Oct-08, Volume: 126

    Topics: Alanine Transaminase; Amitriptyline; Antidepressive Agents; Aspartate Aminotransferases; Clinical En

1964
[TOXICITY STUDIES WITH AMITRIPTYLINE. THERAPEUTIC GUIDE LINES FROM EXPERIMENTAL STUDIES].
    Schweizerische medizinische Wochenschrift, 1965, Jan-30, Volume: 95

    Topics: Amitriptyline; Chlordiazepoxide; Dogs; Electrocardiography; Mice; Parasympathomimetics; Pharmacology

1965
[AMITRYPTILINE POISONING. A CONTRIBUTION TO THE CLINICAL PICTURE. PSYCHIATRIC AND PSYCHOLOGICAL TEST STUDIES ON THE PROBLEM OF THE TOXIC BRAIN DEGERERATION SYNDROME].
    Der Nervenarzt, 1965, Volume: 36

    Topics: Amitriptyline; Antidepressive Agents; Brain; Brain Damage, Chronic; Brain Diseases; Brain Injuries;

1965
[ACUTE POISONING WITH THE PSYCHOPHARMACON AMITRIPTYLINE (SAROTEN)].
    Munchener medizinische Wochenschrift (1950), 1964, Nov-27, Volume: 106

    Topics: Amitriptyline; Coma; Poisoning; Toxicology

1964
AMITRIPTYLINE POISONING.
    Lancet (London, England), 1965, Aug-21, Volume: 2, Issue:7408

    Topics: Amitriptyline; Amobarbital; Barbiturates; Coma; Depression; Depressive Disorder; Diuresis; Drug Ther

1965
[ACUTE INTOXICATION BY AMITRIPTYLINE WITH VENTRICULAR TACHYCARDIA. RECOVERY AFTER CARDIO-RESPIRATORY RESUSCITATION].
    Bulletins et memoires de la Societe medicale des hopitaux de Paris, 1965, Mar-19, Volume: 116

    Topics: Amitriptyline; Heart; Humans; Poisoning; Resuscitation; Tachycardia; Tachycardia, Ventricular; Toxic

1965
AMITRIPTYLINE POISONING.
    Lancet (London, England), 1965, Sep-04, Volume: 2, Issue:7410

    Topics: Amitriptyline; Antidepressive Agents; England; Poisoning; Toxicology

1965
[FATAL CASES OF POISONING WITH PSYCHOPHARMACEUTICALS].
    Beitrage zur gerichtlichen Medizin, 1965, Volume: 23

    Topics: Amitriptyline; Chromatography; Orphenadrine; Poisoning; Psychotropic Drugs; Toxicology

1965
[Identification of the drugs in the mixture using thin-layer chromatography in sudden poisoning cases].
    Medicina (Kaunas, Lithuania), 2003, Volume: 39 Suppl 2

    Topics: Acute Disease; Amitriptyline; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricy

2003
[UV spectrophotometric research of drug mixture in sudden poisoning cases].
    Medicina (Kaunas, Lithuania), 2003, Volume: 39 Suppl 2

    Topics: Acute Disease; Amitriptyline; Codeine; Data Interpretation, Statistical; Fluoxetine; Humans; Poisoni

2003
Amiodarone fails to improve survival in amitriptyline-poisoned mice.
    Clinical toxicology (Philadelphia, Pa.), 2005, Volume: 43, Issue:3

    Topics: Amiodarone; Amitriptyline; Animals; Anti-Arrhythmia Agents; Antidepressive Agents, Tricyclic; Diseas

2005
Relation of postmortem blood alcohol and drug concentrations in fatal poisonings involving amitriptyline, propoxyphene and promazine.
    Human & experimental toxicology, 2005, Volume: 24, Issue:8

    Topics: Amitriptyline; Dextropropoxyphene; Drug Interactions; Ethanol; Finland; Forensic Medicine; Humans; P

2005
Comparative assessment of blood and urine analyses in patients with acute poisonings by medical, narcotic substances and alcohol in clinical toxicology.
    Przeglad lekarski, 2005, Volume: 62, Issue:6

    Topics: Acute Disease; Amitriptyline; Carbamazepine; Central Nervous System Agents; Clozapine; Ethanol; Fema

2005
Prolonged clinical effects in modified-release amitriptyline poisoning.
    Clinical toxicology (Philadelphia, Pa.), 2006, Volume: 44, Issue:1

    Topics: Acidosis; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Central Nerv

2006
Acute amitriptyline intoxication: an analysis of 44 children.
    Human & experimental toxicology, 2006, Volume: 25, Issue:3

    Topics: Adolescent; Amitriptyline; Antidepressive Agents, Tricyclic; Child; Child, Preschool; Drug Overdose;

2006
Charcoal haemoperfusion in amitriptyline poisoning: experience in 20 children.
    Nephrology (Carlton, Vic.), 2008, Volume: 13, Issue:3

    Topics: Acute Disease; Adolescent; Amitriptyline; Antidepressive Agents, Tricyclic; Antidotes; Charcoal; Chi

2008
Clinical effects and treatment of imipramine and amitriptyline poisoning in children.
    British medical journal, 1967, Sep-09, Volume: 3, Issue:5566

    Topics: Accident Prevention; Amitriptyline; Blood Gas Analysis; Child; Chlorpromazine; Electrocardiography;

1967
[Therapy of acute poisoning with orthograde intestinal lavage].
    Deutsche medizinische Wochenschrift (1946), 1983, Jun-24, Volume: 108, Issue:25

    Topics: Amitriptyline; Barbiturates; Diazepam; Dihydropyridines; Glyburide; Humans; Intestines; Mushroom Poi

1983
Studies on the efficacy of gastric lavage as practiced in a large metropolitan hospital.
    Clinical toxicology, 1981, Volume: 18, Issue:5

    Topics: Amitriptyline; Benzodiazepines; Chromatography, Gas; Chromatography, Thin Layer; Emergency Service,

1981
Effects of epinephrine, norepinephrine, magnesium sulfate, and milrinone on survival and the occurrence of arrhythmias in amitriptyline poisoning in the rat.
    Critical care medicine, 1994, Volume: 22, Issue:11

    Topics: Amitriptyline; Analysis of Variance; Animals; Arrhythmias, Cardiac; Cardiotonic Agents; Chi-Square D

1994
Experimental amitriptyline poisoning: treatment of severe cardiovascular toxicity with cardiopulmonary bypass.
    Annals of emergency medicine, 1994, Volume: 23, Issue:3

    Topics: Amitriptyline; Animals; Cardiopulmonary Bypass; Cardiovascular System; Hemodynamics; Male; Poisoning

1994
The study of tricyclic antidepressants in formalin-fixed human liver and formalin solutions.
    Forensic science international, 1993, Volume: 61, Issue:2-3

    Topics: Amitriptyline; Cryopreservation; Desipramine; Drug Overdose; Drug Stability; Embalming; Evaluation S

1993
[Poisoning with a high dose of amitriptyline in a 9-year-old girl].
    Ceskoslovenska pediatrie, 1993, Volume: 48, Issue:8

    Topics: Amitriptyline; Child; Female; Humans; Poisoning; Suicide, Attempted

1993
Epinephrine and sodium bicarbonate independently and additively increase survival in experimental amitriptyline poisoning.
    Critical care medicine, 1997, Volume: 25, Issue:4

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Disease Models, Anim

1997
Amitriptyline-associated seizures in a toddler with Munchausen-by-proxy.
    Pediatric emergency care, 1999, Volume: 15, Issue:6

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Humans; Infant; Munchausen Syndrome by Proxy; Poiso

1999
Among fatal poisonings dextropropoxyphene predominates in younger people, antidepressants in the middle aged and sedatives in the elderly.
    Journal of forensic sciences, 2000, Volume: 45, Issue:1

    Topics: Adult; Age Factors; Aged; Amitriptyline; Antidepressive Agents; Autopsy; Azabicyclo Compounds; Clomi

2000
Efficacy of long duration resuscitation and magnesium sulphate treatment in amitriptyline poisoning.
    European journal of emergency medicine : official journal of the European Society for Emergency Medicine, 2002, Volume: 9, Issue:1

    Topics: Amitriptyline; Anti-Arrhythmia Agents; Antidepressive Agents, Tricyclic; Cardiopulmonary Resuscitati

2002
Drug overdoses: Is one stomach washing enough?
    The New Zealand medical journal, 1975, Feb-26, Volume: 81, Issue:534

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Gas; Gastric Lavage; Humans; Intuba

1975
Medical grand rounds: Tricyclic antidepressant (TCA) overdose.
    Journal of the Tennessee Medical Association, 1978, Volume: 71, Issue:2

    Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Female; Humans; Poisoning

1978
[Hemoperfusion in deliberate drug poisoning. Review and 2 case reports].
    Ugeskrift for laeger, 1978, Apr-24, Volume: 140, Issue:17

    Topics: Aged; Amitriptyline; Barbiturates; Charcoal; Female; Filtration; Hemoperfusion; Humans; Poisoning; R

1978
[Therapeutic plasmapheresis--a new form of adjuvant treatment (author's transl)].
    Medizinische Klinik, 1976, Nov-05, Volume: 71, Issue:45

    Topics: Adult; Amitriptyline; Antilymphocyte Serum; Bone Neoplasms; Female; Hemophilia A; Humans; Hyperthyro

1976
Letter: Amitriptyline and imipramine poisoning in children.
    British medical journal, 1975, Mar-01, Volume: 1, Issue:5956

    Topics: Amitriptyline; Animals; Antidotes; Humans; Imipramine; Phenytoin; Poisoning; Rats; Seizures

1975
Editorial: Toxicity of tricyclic antidepressants.
    JAMA, 1975, Mar-31, Volume: 231, Issue:13

    Topics: Acute Disease; Amitriptyline; Antidepressive Agents; Depression; Drug Utilization; Electrocardiograp

1975
Studies with activated charcoal in the treatment of drug overdosage using the pig as an animal model.
    Archives of toxicology, 1975, Sep-05, Volume: 34, Issue:1

    Topics: Acetaminophen; Administration, Oral; Amitriptyline; Amobarbital; Animals; Charcoal; Disease Models,

1975
Letter: Neostigmine methysulfate in the treatment of cardiac arryhthmia induced by perphenazine-amitriptyline.
    Canadian Medical Association journal, 1976, Jan-24, Volume: 114, Issue:2

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Child, Preschool; Drug Combin

1976
Letter: Non-accidental poisoning and child abuse.
    British medical journal, 1976, May-15, Volume: 1, Issue:6019

    Topics: Adolescent; Amitriptyline; Aspirin; Child; Child Abuse; Female; Humans; Infant; Infant, Newborn; Mal

1976
[Acute heart failure and its treatment in cardiologic drug poisoning].
    Kardiologiia, 1992, Volume: 32, Issue:4

    Topics: Adolescent; Adult; Amitriptyline; Anti-Arrhythmia Agents; Cardiac Glycosides; Heart Arrest; Hemoperf

1992
Diffusion as a mechanism of postmortem drug redistribution: an experimental study in rats.
    International journal of legal medicine, 1992, Volume: 105, Issue:2

    Topics: Amitriptyline; Animals; Evaluation Studies as Topic; Forensic Medicine; Kidney; Liver; Lung; Male; M

1992
[Analysis of 20 cases of amitriptyline poisoning].
    Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, 1992, Volume: 25, Issue:1

    Topics: Adult; Amitriptyline; Female; Humans; Male; Middle Aged; Physostigmine; Poisoning; Seizures

1992
[A case of acute amitriptyline poisoning].
    Medicina clinica, 1992, Apr-11, Volume: 98, Issue:14

    Topics: Acute Disease; Amitriptyline; Hemoperfusion; Humans; Poisoning

1992
Efficacy of dopamine and norepinephrine for treatment of hemodynamic compromise in amitriptyline intoxication.
    Critical care medicine, 1991, Volume: 19, Issue:4

    Topics: Amitriptyline; Animals; Blood Pressure; Cardiac Output; Dogs; Dopamine; Female; Hemodynamics; Male;

1991
[Fatal poisoning caused by the combination propafenone-amitriptyline; apropos of a case].
    Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1988, Volume: 29, Issue:1

    Topics: Adult; Amitriptyline; Diazepam; Drug Combinations; Electrocardiography; Humans; Male; Poisoning; Pro

1988
The role of the laboratory in acute poisoning: case histories.
    Clinical biochemistry, 1986, Volume: 19, Issue:2

    Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Amitriptyline; Ethylene Glycols; Female; Hemoperfus

1986
[Acute management of poisonings].
    Wiener medizinische Wochenschrift (1946), 1986, Mar-31, Volume: 136, Issue:5-6

    Topics: Adult; Amitriptyline; Emetics; Female; First Aid; Gastric Lavage; Hemoperfusion; Humans; Intestinal

1986
Correlation of initial amitriptyline concentration reduction with activated charcoal therapy in overdose patients.
    The American journal of emergency medicine, 1987, Volume: 5, Issue:1

    Topics: Amitriptyline; Charcoal; Female; Male; Poisoning

1987
Anticholinergic poisoning: treatment with physostigmine.
    Pediatrics, 1973, Volume: 52, Issue:3

    Topics: Adolescent; Amitriptyline; Child; Child, Preschool; Chlorpheniramine; Drug Combinations; Female; His

1973
Recovery from massive amitriptyline overdosage.
    Lancet (London, England), 1968, Jun-08, Volume: 1, Issue:7554

    Topics: Adult; Amitriptyline; Female; Humans; Poisoning

1968
Protection of animals against soman (1,2,2-trimethylpropyl methylphosphono-fluoridate) by pretreatment with some other organophosphorus compounds, followed by oxime and atropine.
    Biochemical pharmacology, 1971, Volume: 20, Issue:1

    Topics: Amitriptyline; Animals; Atropine; Bromides; Carbamates; Cholinesterase Inhibitors; Diphosphates; Dru

1971
Chlorprothixene and its metabolites in blood, liver and urine from fatal poisoning.
    Acta pharmacologica et toxicologica, 1974, Volume: 34, Issue:1

    Topics: Adult; Amitriptyline; Autopsy; Barbiturates; Chlorprothixene; Chromatography, Thin Layer; Drug Syner

1974
Letter: Danger of saline emetics in first-aid for poisoning.
    British medical journal, 1974, Sep-28, Volume: 3, Issue:5934

    Topics: Adult; Amitriptyline; Chlorides; Chlorpromazine; Diazepam; Emetics; Female; First Aid; Humans; Imipr

1974
General hospital psychiatry.
    The New Zealand medical journal, 1972, Volume: 76, Issue:486

    Topics: Adolescent; Adult; Age Factors; Aged; Amitriptyline; Amobarbital; Child; Child, Preschool; Chlorprom

1972
Clinical features and treatment of overdosage of monoamine oxidase inhibitors and their interaction with other psychotropic drugs.
    Resuscitation, 1972, Volume: 1, Issue:1

    Topics: Adult; Amitriptyline; Drug Antagonism; Drug Interactions; Drug Synergism; Female; Humans; Imipramine

1972
Contribution of electroencephalography to resuscitation in toxicology.
    Clinical toxicology, 1973, Volume: 6, Issue:2

    Topics: Amitriptyline; Barbiturates; Carbon Monoxide Poisoning; Coma; Electroencephalography; Fungi; Humans;

1973
Studies on the disposition of amitriptyline and other tricyclic antidepressant drugs in man as it relates to the management of the overdosed patient.
    Advances in biochemical psychopharmacology, 1973, Volume: 7

    Topics: Adult; Amitriptyline; Antidepressive Agents; Charcoal; Chromatography, Gas; Desipramine; Female; Gas

1973
Letter: Amitriptyline and imipramine poisoning in children.
    British medical journal, 1974, Jun-01, Volume: 2, Issue:5917

    Topics: Amitriptyline; Child; Enuresis; Heart Diseases; Humans; Imipramine; Phenytoin; Poisoning

1974
Letter: Amitriptyline and imipramine poisoning in children.
    British medical journal, 1974, May-18, Volume: 2, Issue:5915

    Topics: Amitriptyline; Carbon Radioisotopes; Child, Preschool; Humans; Imipramine; Poisoning; Renal Dialysis

1974
Letter: Amitriptyline and imipramine poisoning in children.
    British medical journal, 1974, Jun-29, Volume: 2, Issue:5921

    Topics: Amitriptyline; Child; Humans; Imipramine; Poisoning; Renal Dialysis

1974
Hemodynamic effects of norepinephrine in severe hypnotic drug poisoning with arterial hypotension.
    Acta medica Scandinavica, 1972, Volume: 192, Issue:5

    Topics: Acid-Base Equilibrium; Adult; Aged; Amitriptyline; Blood Pressure; Carbamazepine; Cardiac Output; Ca

1972
[Dialysis of drugs and poisons. 2].
    Medizinische Klinik, 1972, Nov-03, Volume: 67, Issue:44

    Topics: Acetaminophen; Aminopyrine; Amitriptyline; Aspirin; Carbamazepine; Chlordiazepoxide; Chlorpromazine;

1972
[Determination of amitriptyline and metabolites in various organs after fatal poisoning].
    Archiv fur Toxikologie, 1971, Volume: 28, Issue:3

    Topics: Adult; Amitriptyline; Brain; Chromatography, Thin Layer; Humans; Kidney; Liver; Lung; Male; Myocardi

1971
Imipramine poisoning.
    Archives of disease in childhood, 1971, Volume: 46, Issue:250

    Topics: Amitriptyline; Child; Enzymes; Female; Heart Failure; Humans; Imipramine; Poisoning

1971
[Case of tryptizol (amitriptyline) poisoning].
    Arhiv za higijenu rada i toksikologiju, 1971, Volume: 22, Issue:2

    Topics: Adult; Amitriptyline; Diuretics; Female; Humans; Poisoning; Suicide

1971
[Cardiovascular complications in acute poisoning with tricyclic antidepressives].
    Acta clinica Belgica, 1971, Volume: 26, Issue:6

    Topics: Adult; Amitriptyline; Antidepressive Agents; Arrhythmia, Sinus; Bundle-Branch Block; Dibenzocyclohep

1971
Physostigmine therapy in acute tricyclic antidepressant poisoning.
    Clinical toxicology, 1971, Volume: 4, Issue:3

    Topics: Adolescent; Adult; Amitriptyline; Antidepressive Agents; Arrhythmias, Cardiac; Barbiturates; Blood P

1971
Accidental poisoning in children in Uganda.
    British medical journal, 1969, Dec-06, Volume: 4, Issue:5683

    Topics: Amitriptyline; Aspirin; Barbiturates; Child; Child, Preschool; Chloroquine; Codeine; Dapsone; Diazep

1969
[Tricyclic antidepressives--psychopharmaca with limited therapeutic scope].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1969, Oct-15, Volume: 89, Issue:20

    Topics: Adult; Amitriptyline; Electrocardiography; Female; Humans; Imipramine; Infant; Male; Poisoning

1969
[Cardiac complications in acute poisoning].
    Journal de medecine de Bordeaux et du Sud-Ouest, 1967, Volume: 144, Issue:7

    Topics: Adolescent; Adult; Amitriptyline; Arrhythmias, Cardiac; Child; Child, Preschool; Chloroquine; Digita

1967