amitriptyline has been researched along with Parkinson Disease, Secondary in 5 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Parkinson Disease, Secondary: Conditions which feature clinical manifestations resembling primary Parkinson disease that are caused by a known or suspected condition. Examples include parkinsonism caused by vascular injury, drugs, trauma, toxin exposure, neoplasms, infections and degenerative or hereditary conditions. Clinical features may include bradykinesia, rigidity, parkinsonian gait, and masked facies. In general, tremor is less prominent in secondary parkinsonism than in the primary form. (From Joynt, Clinical Neurology, 1998, Ch38, pp39-42)
Excerpt | Relevance | Reference |
---|---|---|
"Haloperidol was implicated in 47 patients (37%), followed by amitriptyline/perphenazine in 30%, thioridazine in 27%, and chlorpromazine in 20%." | 1.28 | Neurologic approach to drug-induced movement disorders: a study of 125 patients. ( Jankovic, J; Miller, LG, 1990) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 4 (80.00) | 18.7374 |
1990's | 1 (20.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Schmidt, LG | 1 |
Grohmann, R | 1 |
Helmchen, H | 1 |
Langscheid-Schmidt, K | 1 |
Müller-Oerlinghausen, B | 1 |
Poser, W | 1 |
Rüther, E | 1 |
Scherer, J | 1 |
Strauss, A | 1 |
Wolf, B | 1 |
Lutz, EG | 1 |
Miller, LG | 1 |
Jankovic, J | 1 |
Braasch, F | 1 |
Ridges, AP | 1 |
Harper, P | 1 |
5 other studies available for amitriptyline and Parkinson Disease, Secondary
Article | Year |
---|---|
Adverse drug reactions. An epidemiological study at psychiatric hospitals.
Topics: Adult; Amitriptyline; Drug Evaluation; Female; Germany, West; Haloperidol; Hospitals, Psychiatric; H | 1984 |
Neuroleptic-induced parkinsonism facilitated by alcohol.
Topics: Amitriptyline; Drug Synergism; Ethanol; Female; Humans; Middle Aged; Parkinson Disease, Secondary; P | 1978 |
Neurologic approach to drug-induced movement disorders: a study of 125 patients.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Amitriptyline; Antipsychotic Agents; Chorea | 1990 |
[Therapy of agitated depression using Saroten retard 75 and psychopathologic reflexions on the disease].
Topics: Alcoholism; Amitriptyline; Delayed-Action Preparations; Depression; Female; Humans; Middle Aged; Par | 1971 |
Pink spot--is it a drug artefact?
Topics: Amitriptyline; Amobarbital; Chlorpromazine; Chromatography; Haloperidol; Humans; Mental Disorders; P | 1970 |