Page last updated: 2024-10-22

amitriptyline and Parkinson Disease, Secondary

amitriptyline has been researched along with Parkinson Disease, Secondary in 5 studies

Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.

Parkinson Disease, Secondary: Conditions which feature clinical manifestations resembling primary Parkinson disease that are caused by a known or suspected condition. Examples include parkinsonism caused by vascular injury, drugs, trauma, toxin exposure, neoplasms, infections and degenerative or hereditary conditions. Clinical features may include bradykinesia, rigidity, parkinsonian gait, and masked facies. In general, tremor is less prominent in secondary parkinsonism than in the primary form. (From Joynt, Clinical Neurology, 1998, Ch38, pp39-42)

Research Excerpts

ExcerptRelevanceReference
"Haloperidol was implicated in 47 patients (37%), followed by amitriptyline/perphenazine in 30%, thioridazine in 27%, and chlorpromazine in 20%."1.28Neurologic approach to drug-induced movement disorders: a study of 125 patients. ( Jankovic, J; Miller, LG, 1990)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19904 (80.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schmidt, LG1
Grohmann, R1
Helmchen, H1
Langscheid-Schmidt, K1
Müller-Oerlinghausen, B1
Poser, W1
Rüther, E1
Scherer, J1
Strauss, A1
Wolf, B1
Lutz, EG1
Miller, LG1
Jankovic, J1
Braasch, F1
Ridges, AP1
Harper, P1

Other Studies

5 other studies available for amitriptyline and Parkinson Disease, Secondary

ArticleYear
Adverse drug reactions. An epidemiological study at psychiatric hospitals.
    Acta psychiatrica Scandinavica, 1984, Volume: 70, Issue:1

    Topics: Adult; Amitriptyline; Drug Evaluation; Female; Germany, West; Haloperidol; Hospitals, Psychiatric; H

1984
Neuroleptic-induced parkinsonism facilitated by alcohol.
    The Journal of the Medical Society of New Jersey, 1978, Volume: 75, Issue:6

    Topics: Amitriptyline; Drug Synergism; Ethanol; Female; Humans; Middle Aged; Parkinson Disease, Secondary; P

1978
Neurologic approach to drug-induced movement disorders: a study of 125 patients.
    Southern medical journal, 1990, Volume: 83, Issue:5

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Amitriptyline; Antipsychotic Agents; Chorea

1990
[Therapy of agitated depression using Saroten retard 75 and psychopathologic reflexions on the disease].
    Der Nervenarzt, 1971, Volume: 42, Issue:12

    Topics: Alcoholism; Amitriptyline; Delayed-Action Preparations; Depression; Female; Humans; Middle Aged; Par

1971
Pink spot--is it a drug artefact?
    Psychiatria clinica, 1970, Volume: 3, Issue:2

    Topics: Amitriptyline; Amobarbital; Chlorpromazine; Chromatography; Haloperidol; Humans; Mental Disorders; P

1970