Page last updated: 2024-10-22

amitriptyline and Paralysis

amitriptyline has been researched along with Paralysis in 3 studies

Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.

Paralysis: A general term most often used to describe severe or complete loss of muscle strength due to motor system disease from the level of the cerebral cortex to the muscle fiber. This term may also occasionally refer to a loss of sensory function. (From Adams et al., Principles of Neurology, 6th ed, p45)

Research Excerpts

ExcerptRelevanceReference
"The authors report three cases of isolated sleep paralysis controlled by L-tryptophan with or without amitriptyline."3.66Serotoninergic agents in the treatment of isolated sleep paralysis. ( Hams, G; Snyder, S, 1982)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kitagawa, N1
Oda, M1
Nobutaka, I1
Satoh, H1
Totoki, T1
Morimoto, M1
Broadley, KJ1
Roberts, DJ1
Snyder, S1
Hams, G1

Other Studies

3 other studies available for amitriptyline and Paralysis

ArticleYear
A proposed mechanism for amitriptyline neurotoxicity based on its detergent nature.
    Toxicology and applied pharmacology, 2006, Nov-15, Volume: 217, Issue:1

    Topics: Amitriptyline; Anesthetics, Local; Animals; Detergents; Dose-Response Relationship, Drug; Electric S

2006
The influence of antidepressant drugs on akinesia produced in mice by intracisternally administered noradrenaline, dopamine and noradnamine.
    Experientia, 1967, Oct-15, Volume: 23, Issue:10

    Topics: Amitriptyline; Animals; Catecholamines; Dopamine; Male; Mice; Movement; Nialamide; Norepinephrine; P

1967
Serotoninergic agents in the treatment of isolated sleep paralysis.
    The American journal of psychiatry, 1982, Volume: 139, Issue:9

    Topics: Adult; Amitriptyline; Female; Humans; Male; Middle Aged; Paralysis; Sleep; Sleep Wake Disorders; Try

1982