Page last updated: 2024-10-22

amitriptyline and Panic Disorder

amitriptyline has been researched along with Panic Disorder in 8 studies

Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.

Panic Disorder: A type of anxiety disorder characterized by unexpected panic attacks that last minutes or, rarely, hours. Panic attacks begin with intense apprehension, fear or terror and, often, a feeling of impending doom. Symptoms experienced during a panic attack include dyspnea or sensations of being smothered; dizziness, loss of balance or faintness; choking sensations; palpitations or accelerated heart rate; shakiness; sweating; nausea or other form of abdominal distress; depersonalization or derealization; paresthesias; hot flashes or chills; chest discomfort or pain; fear of dying and fear of not being in control of oneself or going crazy. Agoraphobia may also develop. Similar to other anxiety disorders, it may be inherited as an autosomal dominant trait.

Research Excerpts

ExcerptRelevanceReference
"Plasma interleukin-1 beta (IL-1 beta) concentrations were measured in 10 outpatients with panic disorder before and on days 30 and 32 of treatment with alprazolam (2-2."3.69Plasma interleukin-1 beta concentrations in panic disorder. ( Bellodi, L; Bertani, A; Brambilla, F; Panerai, A; Perna, G; Sacerdote, P, 1994)
"In the patients with reactive depression, no differences could be detected as compared with the control group."1.29Are affective disorders associated with alterations of heart rate variability? ( Kaschka, WP; Rechlin, T; Spitzer, A; Weis, M, 1994)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (75.00)18.2507
2000's2 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kapoor, S1
Dresler, T1
Ehlis, AC1
Plichta, MM1
Richter, MM1
Jabs, B1
Lesch, KP1
Fallgatter, AJ1
Chung, CK1
Remington, ND1
Suh, BY1
Brambilla, F1
Bellodi, L1
Perna, G1
Bertani, A1
Panerai, A1
Sacerdote, P1
Rechlin, T1
Weis, M1
Spitzer, A1
Kaschka, WP1
Deary, IJ1
Wilson, JA1
Pallanti, S1
Mazzi, D1
Preskorn, SH1
Fast, GA1

Trials

1 trial available for amitriptyline and Panic Disorder

ArticleYear
Problems in treating globus pharyngis.
    Clinical otolaryngology and allied sciences, 1994, Volume: 19, Issue:1

    Topics: Adult; Amitriptyline; Anxiety; Conversion Disorder; Depression; Double-Blind Method; Female; Humans;

1994

Other Studies

7 other studies available for amitriptyline and Panic Disorder

ArticleYear
Psychological associations of irritable bowel syndrome besides panic disorder: an often overlooked reality.
    Scandinavian journal of gastroenterology, 2009, Volume: 44, Issue:1

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Cognitive Behavioral Therapy; Drug Therapy, Combina

2009
Panic disorder and a possible treatment approach by means of high-frequency rTMS: a case report.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2009, Volume: 10, Issue:4 Pt 3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Adult; Amit

2009
Estrogen replacement therapy may reduce panic symptoms.
    The Journal of clinical psychiatry, 1995, Volume: 56, Issue:11

    Topics: Adult; Amitriptyline; Drug Therapy, Combination; Estradiol; Estrogen Replacement Therapy; Estrogens,

1995
Plasma interleukin-1 beta concentrations in panic disorder.
    Psychiatry research, 1994, Volume: 54, Issue:2

    Topics: Adult; Alprazolam; Amitriptyline; Antibodies, Monoclonal; Anxiety; Benzodiazepines; Cytokines; Femal

1994
Are affective disorders associated with alterations of heart rate variability?
    Journal of affective disorders, 1994, Volume: 32, Issue:4

    Topics: Adjustment Disorders; Adult; Amitriptyline; Arousal; Depressive Disorder; Electrocardiography; Femal

1994
MDMA (Ecstasy) precipitation of panic disorder.
    Biological psychiatry, 1992, Jul-01, Volume: 32, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Agoraphobia; Alcohol Drinking; Amitriptyline; Arousal; Fluvoxa

1992
Tricyclic antidepressant-induced seizures and plasma drug concentration.
    The Journal of clinical psychiatry, 1992, Volume: 53, Issue:5

    Topics: Adult; Ambulatory Care; Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipr

1992