amitriptyline has been researched along with Pain, Postoperative in 15 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Pain, Postoperative: Pain during the period after surgery.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effectiveness of amitriptyline in relieving neuropathic pain following treatment of breast cancer was studied in 15 patients in a randomised, double-blind placebo-controlled crossover study." | 9.08 | Amitriptyline effectively relieves neuropathic pain following treatment of breast cancer. ( Eija, K; J, NP; Tiina, T, 1996) |
| "The effectiveness of amitriptyline in relieving neuropathic pain following treatment of breast cancer was studied in 15 patients in a randomised, double-blind placebo-controlled crossover study." | 5.08 | Amitriptyline effectively relieves neuropathic pain following treatment of breast cancer. ( Eija, K; J, NP; Tiina, T, 1996) |
| "Safety and postoperative pain, range of motion, and self-reported function were evaluated for 90 days." | 2.76 | Novel drug OMS103HP reduces pain and improves joint motion and function for 90 days after arthroscopic meniscectomy. ( Demopulos, GA; ElAttrache, NS; Fox, DL; Garrett, WE; Hewitt, MS; Kaeding, CC; O'Donnell, JB; Papilion, JD; Ruvuna, F; Skrepnik, NV; Whitaker, JS; Xerogeanes, JW, 2011) |
| "The authors assessed the participants' postoperative pain by means of a visual analog scale at four, six, eight, 12, 24 and 48 hours." | 2.76 | Evaluation of the muscle relaxant cyclobenzaprine after third-molar extraction. ( Calazans, AC; de Oliveira E Silva, ED; de Santana Santos, T; Gomes, AC; Martins-Filho, PR; Silva, LC, 2011) |
| " We therefore investigated the adverse effects of preoperative intravenous amitriptyline in a typical phase 1A trial." | 2.73 | Phase 1A safety assessment of intravenous amitriptyline. ( Colvin, HP; Fridrich, P; Gerner, P; Hamp, T; Lirk, P; Lukanich, J; Saria, A; Wasan, AD; Zernig, G; Zizza, A, 2007) |
| "Six children with cerebral palsy are presented who developed neuropathic pain following multilevel orthopedic surgery." | 1.33 | Neuropathic pain following multilevel surgery in children with cerebral palsy: a case series and review. ( Lauder, GR; White, MC, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.67) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 5 (33.33) | 29.6817 |
| 2010's | 5 (33.33) | 24.3611 |
| 2020's | 2 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| Anghelescu, DL | 1 |
| Johns, E | 1 |
| Bhatia, S | 1 |
| Frett, MJ | 1 |
| Lu, Z | 1 |
| Al Yafi, MN | 1 |
| ElHawary, H | 1 |
| Al-Halabi, B | 1 |
| Alnaeem, H | 1 |
| Xu, L | 1 |
| Fouda-Neel, O | 1 |
| Raldi, FV | 1 |
| Nascimento, RD | 1 |
| Sato, FRL | 1 |
| Santos, LM | 1 |
| Amorim, JBO | 1 |
| de Moraes, MB | 1 |
| Fanton, GS | 1 |
| Dillingham, MF | 1 |
| Wall, MS | 1 |
| Gillenwater, GE | 1 |
| Khan, AM | 1 |
| Carver, TJ | 1 |
| Perkins, JG | 1 |
| Demopulos, GA | 2 |
| Lacerda-Filho, A | 1 |
| Assunção, GM | 1 |
| de Oliveira, TA | 1 |
| Garrett, WE | 1 |
| Kaeding, CC | 1 |
| ElAttrache, NS | 1 |
| Xerogeanes, JW | 1 |
| Hewitt, MS | 1 |
| Skrepnik, NV | 1 |
| Papilion, JD | 1 |
| O'Donnell, JB | 1 |
| Fox, DL | 1 |
| Ruvuna, F | 1 |
| Whitaker, JS | 1 |
| de Santana Santos, T | 1 |
| Calazans, AC | 1 |
| Martins-Filho, PR | 1 |
| Silva, LC | 1 |
| de Oliveira E Silva, ED | 1 |
| Gomes, AC | 1 |
| Siegel, MG | 1 |
| Fischmeister, MF | 1 |
| Lauder, GR | 1 |
| White, MC | 1 |
| Fridrich, P | 1 |
| Colvin, HP | 1 |
| Zizza, A | 1 |
| Wasan, AD | 1 |
| Lukanich, J | 1 |
| Lirk, P | 1 |
| Saria, A | 1 |
| Zernig, G | 1 |
| Hamp, T | 1 |
| Gerner, P | 1 |
| Kerrick, JM | 1 |
| Fine, PG | 1 |
| Lipman, AG | 1 |
| Love, G | 1 |
| Eija, K | 1 |
| Tiina, T | 1 |
| J, NP | 1 |
| Kohjitani, A | 1 |
| Miyawaki, T | 1 |
| Kasuya, K | 1 |
| Shimada, M | 1 |
| Levine, JD | 1 |
| Gordon, NC | 1 |
| Smith, R | 1 |
| McBryde, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| "A Prospective, Randomized Study of the Possible Pain Relieving and Scar Tissue Modifying Properties of Lipotransplantation in a Post Breast Therapy Pain Syndrome Setting"[NCT01888419] | 18 participants (Actual) | Interventional | 2014-10-31 | Completed | |||
| Comparative Evaluation of Osteopathy Treatment Efficacy in Pain Support After Breast Surgery in Oncology[NCT01403168] | 28 participants (Actual) | Interventional | 2011-04-30 | Terminated (stopped due to Recruitment difficulties) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 trials available for amitriptyline and Pain, Postoperative
| Article | Year |
|---|---|
Pain control following alloplastic breast reconstruction with muscle relaxant: A randomized controlled trial.
Topics: Adult; Amitriptyline; Drug Administration Schedule; Female; Humans; Mammaplasty; Middle Aged; Muscle | 2021 |
Novel drug product to improve joint motion and function and reduce pain after arthroscopic anterior cruciate ligament reconstruction.
Topics: Adult; Amitriptyline; Analgesics; Anterior Cruciate Ligament; Anterior Cruciate Ligament Injuries; A | 2008 |
Novel drug OMS103HP reduces pain and improves joint motion and function for 90 days after arthroscopic meniscectomy.
Topics: Adolescent; Adult; Aged; Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthrosc | 2011 |
Evaluation of the muscle relaxant cyclobenzaprine after third-molar extraction.
Topics: Acetaminophen; Adolescent; Adult; Amitriptyline; Analgesics, Non-Narcotic; Double-Blind Method; Edem | 2011 |
Phase 1A safety assessment of intravenous amitriptyline.
Topics: Adult; Aged; Amitriptyline; Analgesics, Non-Narcotic; Bradycardia; Cohort Studies; Dose-Response Rel | 2007 |
Low-dose amitriptyline as an adjunct to opioids for postoperative orthopedic pain: a placebo-controlled trial.
Topics: Adolescent; Adult; Aged; Amitriptyline; Dose-Response Relationship, Drug; Drug Therapy, Combination; | 1993 |
Amitriptyline effectively relieves neuropathic pain following treatment of breast cancer.
Topics: Adult; Aged; Amitriptyline; Analgesics, Non-Narcotic; Anxiety; Breast Neoplasms; Cross-Over Studies; | 1996 |
Amitriptyline effectively relieves neuropathic pain following treatment of breast cancer.
Topics: Adult; Aged; Amitriptyline; Analgesics, Non-Narcotic; Anxiety; Breast Neoplasms; Cross-Over Studies; | 1996 |
Amitriptyline effectively relieves neuropathic pain following treatment of breast cancer.
Topics: Adult; Aged; Amitriptyline; Analgesics, Non-Narcotic; Anxiety; Breast Neoplasms; Cross-Over Studies; | 1996 |
Amitriptyline effectively relieves neuropathic pain following treatment of breast cancer.
Topics: Adult; Aged; Amitriptyline; Analgesics, Non-Narcotic; Anxiety; Breast Neoplasms; Cross-Over Studies; | 1996 |
Desipramine enhances opiate postoperative analgesia.
Topics: Amitriptyline; Analgesia; Desipramine; Double-Blind Method; Drug Combinations; Drug Therapy, Combina | 1986 |
7 other studies available for amitriptyline and Pain, Postoperative
| Article | Year |
|---|---|
Chronic postsurgical pain in children and young adults with cancer and choice of regional anesthesia for amputation and limb-sparing surgery.
Topics: Amitriptyline; Amputation, Surgical; Anesthesia, Conduction; Child; Chronic Pain; Humans; Neoplasms; | 2023 |
Evaluation of the impact of preoperative use of dexamethasone and cyclobenzaprine in surgical extraction of lower third molars on trismus by electromyographic analysis.
Topics: Amitriptyline; Dexamethasone; Edema; Humans; Molar, Third; Pain, Postoperative; Prospective Studies; | 2019 |
Neuropathic pain after stapled hemorrhoidopexy.
Topics: Adult; Amines; Amitriptyline; Anal Canal; Analgesics; Cyclohexanecarboxylic Acids; Follow-Up Studies | 2009 |
Regarding the novel drug OMS103HP.
Topics: Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthroscopy; Female; Humans; Keto | 2012 |
Novel drug in arthroscopic meniscectomy.
Topics: Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthroscopy; Female; Humans; Keto | 2012 |
Neuropathic pain following multilevel surgery in children with cerebral palsy: a case series and review.
Topics: Adolescent; Amines; Amitriptyline; Analgesics; Antidepressive Agents, Tricyclic; Cerebral Palsy; Chi | 2005 |
Sympathetic activity-mediated neuropathic facial pain following simple tooth extraction: a case report.
Topics: Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Autonomic Nerve Block; Electroacupuncture; Fa | 2002 |