amitriptyline has been researched along with Osteosarcoma in 3 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Osteosarcoma: A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To propose clonazepam for use in the empiric treatment of shooting/shocking phantom limb pain." | 7.69 | Clonazepam for the treatment of lancinating phantom limb pain. ( Bartusch, SL; D'Alessio, JG; Jernigan, JR; Sanders, BJ, 1996) |
| "To propose clonazepam for use in the empiric treatment of shooting/shocking phantom limb pain." | 3.69 | Clonazepam for the treatment of lancinating phantom limb pain. ( Bartusch, SL; D'Alessio, JG; Jernigan, JR; Sanders, BJ, 1996) |
| "This severe pain is mostly refractory to palliative analgesic treatment, and the latter was only detected by specific and sensitive outcomes." | 2.87 | Pain characterization and response to palliative care in dogs with naturally-occurring appendicular osteosarcoma: An open label clinical trial. ( Beauchamp, G; Blair, J; de Lorimier, LP; Lussier, B; Monteiro, BP; Moreau, M; Pelletier, JP; Troncy, E, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Monteiro, BP | 1 |
| de Lorimier, LP | 1 |
| Moreau, M | 1 |
| Beauchamp, G | 1 |
| Blair, J | 1 |
| Lussier, B | 1 |
| Pelletier, JP | 1 |
| Troncy, E | 1 |
| Bartusch, SL | 1 |
| Sanders, BJ | 1 |
| D'Alessio, JG | 1 |
| Jernigan, JR | 1 |
| Rogers, AG | 1 |
1 trial available for amitriptyline and Osteosarcoma
| Article | Year |
|---|---|
Pain characterization and response to palliative care in dogs with naturally-occurring appendicular osteosarcoma: An open label clinical trial.
Topics: Amitriptyline; Analgesics; Animals; Bone Neoplasms; Central Nervous System Sensitization; Dog Diseas | 2018 |
2 other studies available for amitriptyline and Osteosarcoma
| Article | Year |
|---|---|
Clonazepam for the treatment of lancinating phantom limb pain.
Topics: Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Clonazepam; Disarticulation; Drug Therapy, Co | 1996 |
Use of amitriptyline (Elavil) for phantom limb pain in younger children.
Topics: Administration, Oral; Amitriptyline; Amputation, Surgical; Child; Femoral Neoplasms; Humans; Male; O | 1989 |