amitriptyline has been researched along with Osteoarthritis of Knee in 1 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Antidepressants, such as amitriptyline, have been used to treat chronic pain in other conditions." | 5.41 | Effect of low-dose amitriptyline on reducing pain in clinical knee osteoarthritis compared to benztropine: study protocol of a randomised, double blind, placebo-controlled trial. ( Arnold, C; Cicuttini, FM; Forbes, A; Hussain, SM; Teichtahl, AJ; Urquhart, DM; Wang, Y; Wluka, AE, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wluka, AE | 1 |
| Urquhart, DM | 1 |
| Teichtahl, AJ | 1 |
| Hussain, SM | 1 |
| Forbes, A | 1 |
| Arnold, C | 1 |
| Wang, Y | 1 |
| Cicuttini, FM | 1 |
1 trial available for amitriptyline and Osteoarthritis of Knee
| Article | Year |
|---|---|
Effect of low-dose amitriptyline on reducing pain in clinical knee osteoarthritis compared to benztropine: study protocol of a randomised, double blind, placebo-controlled trial.
Topics: Amitriptyline; Australia; Benztropine; Chronic Pain; Double-Blind Method; Humans; Osteoarthritis, Kn | 2021 |