Page last updated: 2024-10-22

amitriptyline and Opioid-Related Disorders

amitriptyline has been researched along with Opioid-Related Disorders in 2 studies

Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.

Opioid-Related Disorders: Disorders related to or resulting from abuse or misuse of OPIOIDS.

Research Excerpts

ExcerptRelevanceReference
"Benzodiazepine use in the treatment of insomnia may cause benzodiazepine dependence, especially in opiate users."2.69Amitriptyline vs. lorazepam in the treatment of opiate-withdrawal insomnia: a randomized double-blind study. ( Jarusuraisin, N; Srisurapanont, M, 1998)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Tang, J1
Landes, RD1
Srisurapanont, M1
Jarusuraisin, N1

Trials

1 trial available for amitriptyline and Opioid-Related Disorders

ArticleYear
Amitriptyline vs. lorazepam in the treatment of opiate-withdrawal insomnia: a randomized double-blind study.
    Acta psychiatrica Scandinavica, 1998, Volume: 97, Issue:3

    Topics: Adult; Amitriptyline; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Double-Blind Method; Fe

1998

Other Studies

1 other study available for amitriptyline and Opioid-Related Disorders

ArticleYear
Some t-tests for N-of-1 trials with serial correlation.
    PloS one, 2020, Volume: 15, Issue:2

    Topics: Amitriptyline; Clinical Trials as Topic; Fibromyalgia; Humans; Monte Carlo Method; Opioid-Related Di

2020