amitriptyline has been researched along with Opioid-Related Disorders in 2 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Opioid-Related Disorders: Disorders related to or resulting from abuse or misuse of OPIOIDS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Benzodiazepine use in the treatment of insomnia may cause benzodiazepine dependence, especially in opiate users." | 2.69 | Amitriptyline vs. lorazepam in the treatment of opiate-withdrawal insomnia: a randomized double-blind study. ( Jarusuraisin, N; Srisurapanont, M, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tang, J | 1 |
| Landes, RD | 1 |
| Srisurapanont, M | 1 |
| Jarusuraisin, N | 1 |
1 trial available for amitriptyline and Opioid-Related Disorders
| Article | Year |
|---|---|
Amitriptyline vs. lorazepam in the treatment of opiate-withdrawal insomnia: a randomized double-blind study.
Topics: Adult; Amitriptyline; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Double-Blind Method; Fe | 1998 |
1 other study available for amitriptyline and Opioid-Related Disorders
| Article | Year |
|---|---|
Some t-tests for N-of-1 trials with serial correlation.
Topics: Amitriptyline; Clinical Trials as Topic; Fibromyalgia; Humans; Monte Carlo Method; Opioid-Related Di | 2020 |