amitriptyline has been researched along with Ophthalmoplegia, Progressive Supranuclear in 4 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A patient with progressive supranuclear palsy (PSP) showing severe akinesia, postural instability and gait disturbance like frozen gait was treated with amitriptyline (30 mg/day)." | 1.29 | [A case of progressive supranuclear palsy showing marked improvements of frontal hypoperfusion, as well as parkinsonism with amitriptyline]. ( Asanuma, M; Hirata, H; Kondo, Y; Ogawa, N, 1993) |
| " Dosing must be individualized for optimal response and minimal toxicity." | 1.29 | Treatment of progressive supranuclear palsy with amitriptyline: therapeutic and toxic effects. ( Engel, PA, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Asanuma, M | 1 |
| Hirata, H | 1 |
| Kondo, Y | 1 |
| Ogawa, N | 1 |
| Nieforth, KA | 1 |
| Golbe, LI | 1 |
| Engel, PA | 1 |
| Yamashi, M | 1 |
| Sanada, J | 1 |
| Miyazaki, Y | 1 |
| Ikeda, H | 1 |
4 other studies available for amitriptyline and Ophthalmoplegia, Progressive Supranuclear
| Article | Year |
|---|---|
[A case of progressive supranuclear palsy showing marked improvements of frontal hypoperfusion, as well as parkinsonism with amitriptyline].
Topics: Amitriptyline; Animals; Cerebrovascular Circulation; Female; Frontal Lobe; Gait; Humans; Middle Aged | 1993 |
Retrospective study of drug response in 87 patients with progressive supranuclear palsy.
Topics: Amitriptyline; Carbidopa; Humans; Imipramine; Levodopa; Retrospective Studies; Supranuclear Palsy, P | 1993 |
Treatment of progressive supranuclear palsy with amitriptyline: therapeutic and toxic effects.
Topics: Activities of Daily Living; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Confusion; Dose-R | 1996 |
[Short-term treatment of progressive supranuclear palsy with amitriptyline].
Topics: Aged; Amitriptyline; Female; Humans; Male; Middle Aged; Supranuclear Palsy, Progressive | 1986 |