amitriptyline has been researched along with Obesity in 14 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
| Excerpt | Relevance | Reference |
|---|---|---|
| " Corresponding to increase in plasma ceramide, the HFD significantly increased the body weight gain, plasma leptin concentration, urinary total protein and albumin excretion, glomerular damage index, and adipose tissue ASMase activity compared with the LFD-fed mice." | 3.76 | Role of sphingolipid mediator ceramide in obesity and renal injury in mice fed a high-fat diet. ( Boini, KM; Li, PL; Poklis, JL; Xia, M; Zhang, C, 2010) |
| " We studied lipoprotein composition, insulin sensitivity (quantitative insulin sensitivity check index), and saliva cortisol in 78 depressed patients before and after 35 days of amitriptyline or paroxetin treatment." | 3.72 | Lipid metabolism and insulin resistance in depressed patients: significance of weight, hypercortisolism, and antidepressant treatment. ( Deuschle, M; Gilles, M; Henn, FA; Heuser, I; Kopf, D; Lederbogen, F; Lehnert, H; Luley, CW; Ritter, S; Weber-Hamann, B; Westphal, S, 2004) |
| "We present a novel case of migraine headache in a gentleman with Klinefelter's syndrome and HFI, along with a discussion of possible pathophysiologic mechanisms underlying both the headache and the HFI." | 1.34 | Headache in a patient with Klinefelter's syndrome and hyperostosis frontalis interna. ( Liebeskind, DS; Ramchandren, S, 2007) |
| " Three months later the dosage was reduced to 100 mg mexiletine and 25 mg Amitriptyline daily." | 1.33 | [An uncommon cause of recurrent abdominal pain in a 63-year-old obese woman]. ( Schuppert, F; Tiesmeier, J; Warnecke, H, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (42.86) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chaput, JP | 1 |
| Molobe, LT | 1 |
| Shifa, J | 1 |
| Silava, C | 1 |
| Mojela, K | 1 |
| Cainelli, F | 1 |
| Vento, S | 1 |
| Boini, KM | 1 |
| Zhang, C | 1 |
| Xia, M | 1 |
| Poklis, JL | 1 |
| Li, PL | 1 |
| ARENILLAS, L | 1 |
| BATTERMAN, RC | 1 |
| KAUFMAN, JE | 1 |
| MOURATOFF, GJ | 1 |
| Kopf, D | 1 |
| Westphal, S | 1 |
| Luley, CW | 1 |
| Ritter, S | 1 |
| Gilles, M | 1 |
| Weber-Hamann, B | 1 |
| Lederbogen, F | 1 |
| Lehnert, H | 1 |
| Henn, FA | 1 |
| Heuser, I | 1 |
| Deuschle, M | 1 |
| George, R | 1 |
| Poonnoose, P | 1 |
| Isaiah, R | 1 |
| Meyer, MA | 1 |
| Tiesmeier, J | 1 |
| Warnecke, H | 1 |
| Schuppert, F | 1 |
| Ramchandren, S | 1 |
| Liebeskind, DS | 1 |
| Rockwell, WJ | 1 |
| Ellinwood, EH | 1 |
| Trader, DW | 1 |
| Cairella, M | 1 |
| Kendler, KS | 1 |
| Silverstone, T | 1 |
| Goodall, E | 1 |
2 reviews available for amitriptyline and Obesity
| Article | Year |
|---|---|
Psychotropic drugs promoting weight gain: health risks and treatment implications.
Topics: Amitriptyline; Antipsychotic Agents; Body Weight; Chlorpromazine; Energy Intake; Female; Humans; Lit | 1983 |
Serotoninergic mechanisms in human feeding: the pharmacological evidence.
Topics: Amitriptyline; Antipsychotic Agents; Cyproheptadine; Diet; Feeding Behavior; Fenfluramine; Food Pref | 1986 |
12 other studies available for amitriptyline and Obesity
| Article | Year |
|---|---|
Screen time associated with adolescent obesity and obesity risk factors.
Topics: Adolescent; Amitriptyline; Child; Humans; Migraine Disorders; Obesity; Pediatric Obesity; Risk Facto | 2017 |
Primary pseudotumor cerebri syndrome in a young obese African woman.
Topics: Acetazolamide; Adrenergic Uptake Inhibitors; Adult; Amitriptyline; Antihypertensive Agents; Diuretic | 2014 |
Role of sphingolipid mediator ceramide in obesity and renal injury in mice fed a high-fat diet.
Topics: Adipose Tissue; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Blood Pressure; Body Weigh | 2010 |
AMITRIPTYLINE AND BODY-WEIGHT.
Topics: Amitriptyline; Body Weight; Obesity; Toxicology | 1964 |
CLINICAL USE OF AMITRIPTYLINE FOR THE TREATMENT OF PSYCHONEUROTIC REACTIVE ANXIETY AND DEPRESSION.
Topics: Amitriptyline; Anxiety; Arthritis, Rheumatoid; Asthma; Coronary Disease; Depression; Diabetes Mellit | 1964 |
Lipid metabolism and insulin resistance in depressed patients: significance of weight, hypercortisolism, and antidepressant treatment.
Topics: Adult; Aged; Aged, 80 and over; Amitriptyline; Analysis of Variance; Antidepressive Agents; Blood Gl | 2004 |
Dercum's disease (Adiposis dolorosa): delayed diagnosis in a patient with cervical cancer.
Topics: Adiposis Dolorosa; Adult; Amitriptyline; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Antide | 2004 |
Persistent low back pain.
Topics: Amitriptyline; Analgesics, Non-Narcotic; Chronic Disease; Humans; Low Back Pain; Muscle Relaxants, C | 2005 |
[An uncommon cause of recurrent abdominal pain in a 63-year-old obese woman].
Topics: Abdominal Pain; Adiposis Dolorosa; Amitriptyline; Analgesics, Non-Narcotic; Diagnosis, Differential; | 2006 |
Headache in a patient with Klinefelter's syndrome and hyperostosis frontalis interna.
Topics: Adult; Amitriptyline; Analgesics, Non-Narcotic; Humans; Hyperostosis Frontalis Interna; Ischemic Att | 2007 |
[Drugs inducing obesity].
Topics: Adrenal Cortex Hormones; Amitriptyline; Antidepressive Agents; Antihypertensive Agents; Antipsychoti | 1984 |
Amitriptyline-induced obesity in anorexia nervosa: a case report.
Topics: Adult; Amitriptyline; Anorexia Nervosa; Female; Humans; Obesity | 1978 |