amitriptyline has been researched along with Neuritis in 4 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Neuritis: A general term indicating inflammation of a peripheral or cranial nerve. Clinical manifestation may include PAIN; PARESTHESIAS; PARESIS; or HYPESTHESIA.
Excerpt | Relevance | Reference |
---|---|---|
"Neither amitriptyline nor mexiletine provide significant pain relief in patients with HIV-associated painful sensory neuropathy." | 9.08 | A randomized trial of amitriptyline and mexiletine for painful neuropathy in HIV infection. AIDS Clinical Trial Group 242 Protocol Team. ( Clifford, DB; Cohen, B; Dal Pan, GJ; Ellis, RJ; Hall, CD; Kieburtz, K; Marra, CM; Max, MB; McKendall, R; Simpson, D; Singer, E; Tucker, T; Yiannoutsos, C, 1998) |
"Neither amitriptyline nor mexiletine provide significant pain relief in patients with HIV-associated painful sensory neuropathy." | 5.08 | A randomized trial of amitriptyline and mexiletine for painful neuropathy in HIV infection. AIDS Clinical Trial Group 242 Protocol Team. ( Clifford, DB; Cohen, B; Dal Pan, GJ; Ellis, RJ; Hall, CD; Kieburtz, K; Marra, CM; Max, MB; McKendall, R; Simpson, D; Singer, E; Tucker, T; Yiannoutsos, C, 1998) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (25.00) | 18.7374 |
1990's | 1 (25.00) | 18.2507 |
2000's | 2 (50.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Kumar, S | 1 |
Lalwani, K | 1 |
Shoham, A | 1 |
Koh, JL | 1 |
McGraw, T | 1 |
Kieburtz, K | 1 |
Simpson, D | 1 |
Yiannoutsos, C | 1 |
Max, MB | 1 |
Hall, CD | 1 |
Ellis, RJ | 1 |
Marra, CM | 1 |
McKendall, R | 1 |
Singer, E | 1 |
Dal Pan, GJ | 1 |
Clifford, DB | 1 |
Tucker, T | 1 |
Cohen, B | 1 |
Jameson, RM | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
A Phase II/III Double-Blind Study of Amitriptyline and Mexiletine for Painful Neuropathy in HIV Infection[NCT00000793] | Phase 2 | 240 participants | Interventional | Completed | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
1 trial available for amitriptyline and Neuritis
Article | Year |
---|---|
A randomized trial of amitriptyline and mexiletine for painful neuropathy in HIV infection. AIDS Clinical Trial Group 242 Protocol Team.
Topics: Adrenergic Uptake Inhibitors; Adult; Amitriptyline; Anti-Arrhythmia Agents; Double-Blind Method; Dru | 1998 |
3 other studies available for amitriptyline and Neuritis
Article | Year |
---|---|
Painful mononeuritis multiplex in idiopathic thrombocytopenic purpura.
Topics: Amitriptyline; Analgesics, Non-Narcotic; Anticonvulsants; Carbamazepine; Child; Drug Therapy, Combin | 2005 |
Use of oxcarbazepine to treat a pediatric patient with resistant complex regional pain syndrome.
Topics: Amines; Amitriptyline; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; | 2005 |
Management of the bladder in non-traumatic paraplegia.
Topics: Amitriptyline; Female; Humans; Imipramine; Male; Multiple Sclerosis; Myelitis; Neoplasm Metastasis; | 1974 |