Page last updated: 2024-10-22

amitriptyline and Neuritis

amitriptyline has been researched along with Neuritis in 4 studies

Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.

Neuritis: A general term indicating inflammation of a peripheral or cranial nerve. Clinical manifestation may include PAIN; PARESTHESIAS; PARESIS; or HYPESTHESIA.

Research Excerpts

ExcerptRelevanceReference
"Neither amitriptyline nor mexiletine provide significant pain relief in patients with HIV-associated painful sensory neuropathy."9.08A randomized trial of amitriptyline and mexiletine for painful neuropathy in HIV infection. AIDS Clinical Trial Group 242 Protocol Team. ( Clifford, DB; Cohen, B; Dal Pan, GJ; Ellis, RJ; Hall, CD; Kieburtz, K; Marra, CM; Max, MB; McKendall, R; Simpson, D; Singer, E; Tucker, T; Yiannoutsos, C, 1998)
"Neither amitriptyline nor mexiletine provide significant pain relief in patients with HIV-associated painful sensory neuropathy."5.08A randomized trial of amitriptyline and mexiletine for painful neuropathy in HIV infection. AIDS Clinical Trial Group 242 Protocol Team. ( Clifford, DB; Cohen, B; Dal Pan, GJ; Ellis, RJ; Hall, CD; Kieburtz, K; Marra, CM; Max, MB; McKendall, R; Simpson, D; Singer, E; Tucker, T; Yiannoutsos, C, 1998)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's1 (25.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kumar, S1
Lalwani, K1
Shoham, A1
Koh, JL1
McGraw, T1
Kieburtz, K1
Simpson, D1
Yiannoutsos, C1
Max, MB1
Hall, CD1
Ellis, RJ1
Marra, CM1
McKendall, R1
Singer, E1
Dal Pan, GJ1
Clifford, DB1
Tucker, T1
Cohen, B1
Jameson, RM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase II/III Double-Blind Study of Amitriptyline and Mexiletine for Painful Neuropathy in HIV Infection[NCT00000793]Phase 2240 participants InterventionalCompleted
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for amitriptyline and Neuritis

ArticleYear
A randomized trial of amitriptyline and mexiletine for painful neuropathy in HIV infection. AIDS Clinical Trial Group 242 Protocol Team.
    Neurology, 1998, Volume: 51, Issue:6

    Topics: Adrenergic Uptake Inhibitors; Adult; Amitriptyline; Anti-Arrhythmia Agents; Double-Blind Method; Dru

1998

Other Studies

3 other studies available for amitriptyline and Neuritis

ArticleYear
Painful mononeuritis multiplex in idiopathic thrombocytopenic purpura.
    Indian pediatrics, 2005, Volume: 42, Issue:6

    Topics: Amitriptyline; Analgesics, Non-Narcotic; Anticonvulsants; Carbamazepine; Child; Drug Therapy, Combin

2005
Use of oxcarbazepine to treat a pediatric patient with resistant complex regional pain syndrome.
    The journal of pain, 2005, Volume: 6, Issue:10

    Topics: Amines; Amitriptyline; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants;

2005
Management of the bladder in non-traumatic paraplegia.
    Paraplegia, 1974, Volume: 12, Issue:2

    Topics: Amitriptyline; Female; Humans; Imipramine; Male; Multiple Sclerosis; Myelitis; Neoplasm Metastasis;

1974