amitriptyline has been researched along with Necrosis in 5 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report a case of patchy full thickness skin necrosis following drug overdose with amitriptyline, that required excision and split skin grafting." | 7.70 | Drug induced blistering and the plastic surgeon: a case of amitriptyline induced skin necrosis. ( Fogarty, BJ; Khan, K, 1999) |
| "We report a case of patchy full thickness skin necrosis following drug overdose with amitriptyline, that required excision and split skin grafting." | 3.70 | Drug induced blistering and the plastic surgeon: a case of amitriptyline induced skin necrosis. ( Fogarty, BJ; Khan, K, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sabet, LM | 1 |
| Fogarty, BJ | 1 |
| Khan, K | 1 |
| Herschthal, D | 1 |
| Robinson, MJ | 1 |
| Getz, MA | 1 |
| Subramanian, R | 1 |
| Logemann, T | 1 |
| Ballantyne, F | 1 |
| Brackenridge, RG | 1 |
| Peters, TJ | 1 |
| Watson, JM | 1 |
5 other studies available for amitriptyline and Necrosis
| Article | Year |
|---|---|
Bilateral symmetrical brain lesions in tricyclic antidepressant overdosage.
Topics: Adult; Amitriptyline; Brain; Brain Diseases; Cerebral Hemorrhage; Corpus Striatum; Female; Globus Pa | 1980 |
Drug induced blistering and the plastic surgeon: a case of amitriptyline induced skin necrosis.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Drug Eruptions; Humans; Male; Necrosis; Skin | 1999 |
Blisters of the skin in coma induced by amitriptyline and clorazepate dipotassium. Report of a case with underlying sweat gland necrosis.
Topics: Adult; Amitriptyline; Anti-Anxiety Agents; Blister; Clorazepate Dipotassium; Coma; Female; Humans; N | 1979 |
Acute necrotizing eosinophilic myocarditis as a manifestation of severe hypersensitivity myocarditis. Antemortem diagnosis and successful treatment.
Topics: Adult; Amitriptyline; Cardiomyopathy, Dilated; Drug Hypersensitivity; Eosinophilia; Female; Humans; | 1991 |
Myocardial damage in amitriptyline and nortriptyline poisoning.
Topics: Adult; Alanine Transaminase; Amitriptyline; Aspartate Aminotransferases; Cardiomyopathies; Electroca | 1968 |