Page last updated: 2024-10-22

amitriptyline and Nausea

amitriptyline has been researched along with Nausea in 15 studies

Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.

Nausea: An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses.

Research Excerpts

ExcerptRelevanceReference
"Fluoxetine, a specific serotonin reuptake inhibitor, was compared to amitriptyline in the treatment of 51 outpatients with primary major depressive disorder."9.05A double-blind controlled clinical trial of fluoxetine and amitriptyline in the treatment of outpatients with major depressive disorder. ( Chouinard, G, 1985)
"The efficacy and safety of fluoxetine, a new antidepressant agent, were assessed in a double-blind, parallel, randomized study of 44 outpatients with major depressive disorder."9.05A comparative trial of fluoxetine and amitriptyline in patients with major depressive disorder. ( Feighner, JP, 1985)
"Headache is one of the most frequently reported symptoms in post-COVID patients."5.72Amitriptyline for post-COVID headache: effectiveness, tolerability, and response predictors. ( Arias-Rivas, S; Gago-Veiga, AB; García-Azorín, D; Gonzalez-Martinez, A; Guerrero-Peral, ÁL; Sierra, Á; Silva, L, 2022)
"Fluoxetine, a specific serotonin reuptake inhibitor, was compared to amitriptyline in the treatment of 51 outpatients with primary major depressive disorder."5.05A double-blind controlled clinical trial of fluoxetine and amitriptyline in the treatment of outpatients with major depressive disorder. ( Chouinard, G, 1985)
"The efficacy and safety of fluoxetine, a new antidepressant agent, were assessed in a double-blind, parallel, randomized study of 44 outpatients with major depressive disorder."5.05A comparative trial of fluoxetine and amitriptyline in patients with major depressive disorder. ( Feighner, JP, 1985)
" On the other hand, patients with divalproex exhibited significantly higher risk of nausea compared to those with placebo, topiramate, propranolol, gabapentin and amitriptyline."4.95Unveiling the relative efficacy, safety and tolerability of prophylactic medications for migraine: pairwise and network-meta analysis. ( He, A; Li, C; Song, D; Zhang, L, 2017)
"Headache is one of the most frequently reported symptoms in post-COVID patients."1.72Amitriptyline for post-COVID headache: effectiveness, tolerability, and response predictors. ( Arias-Rivas, S; Gago-Veiga, AB; García-Azorín, D; Gonzalez-Martinez, A; Guerrero-Peral, ÁL; Sierra, Á; Silva, L, 2022)
"Chronic nausea is a major, disabling symptom that requires increased recognition as a separate functional entity."1.40Chronic idiopathic nausea of childhood. ( Chelimsky, G; Kovacic, K; Li, BU; Miranda, A; Simpson, P; Williams, S, 2014)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19908 (53.33)18.7374
1990's1 (6.67)18.2507
2000's0 (0.00)29.6817
2010's5 (33.33)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Gonzalez-Martinez, A1
Guerrero-Peral, ÁL1
Arias-Rivas, S1
Silva, L1
Sierra, Á1
Gago-Veiga, AB1
García-Azorín, D1
Martin, CM1
Keller, K1
Beule, J1
Dippold, W1
Kovacic, K1
Miranda, A1
Chelimsky, G1
Williams, S1
Simpson, P1
Li, BU1
He, A1
Song, D1
Zhang, L1
Li, C1
Liao, KY1
Chang, FY1
Wu, LT1
Wu, TC1
VERGA, G1
Guy, W1
Ban, TA1
McEvoy, JP1
Petrie, WM1
Wilson, WH1
Schaffer, JD1
Gualtieri, CT1
Staye, J1
Martin, M1
Diaz-Rubio, E1
Casado, A1
Dominguez, S1
Sastre, J1
Chouinard, G1
Feighner, JP1
Kabes, J1
Taussigová, D1
Dostál, T1
Vinar, O1
Gayford, JJ1
Redpath, TH1
Gannon, P1
Itil, T1
Keskiner, A1
Hsu, B1

Reviews

2 reviews available for amitriptyline and Nausea

ArticleYear
Unveiling the relative efficacy, safety and tolerability of prophylactic medications for migraine: pairwise and network-meta analysis.
    The journal of headache and pain, 2017, Volume: 18, Issue:1

    Topics: Adult; Amines; Amitriptyline; Anticonvulsants; Cyclohexanecarboxylic Acids; Dizziness; Female; Fruct

2017
The side-effects of carbamazepine.
    Proceedings of the Royal Society of Medicine, 1969, Volume: 62, Issue:6

    Topics: Amitriptyline; Anemia, Aplastic; Carbamazepine; Dibenzazepines; Gastrointestinal Diseases; Humans; I

1969

Trials

4 trials available for amitriptyline and Nausea

ArticleYear
A collaborative study of a new antidepressant, viloxazine, in neurotic and endogenous depressives.
    International pharmacopsychiatry, 1982, Volume: 17, Issue:1

    Topics: Adolescent; Adult; Amitriptyline; Clinical Trials as Topic; Depressive Disorder; Dizziness; Doxepin;

1982
A double-blind controlled clinical trial of fluoxetine and amitriptyline in the treatment of outpatients with major depressive disorder.
    The Journal of clinical psychiatry, 1985, Volume: 46, Issue:3 Pt 2

    Topics: Adult; Ambulatory Care; Amitriptyline; Anxiety; Body Weight; Clinical Trials as Topic; Depressive Di

1985
A comparative trial of fluoxetine and amitriptyline in patients with major depressive disorder.
    The Journal of clinical psychiatry, 1985, Volume: 46, Issue:9

    Topics: Adult; Aged; Akathisia, Drug-Induced; Ambulatory Care; Amitriptyline; Clinical Trials as Topic; Depr

1985
Clinical and quantitative electroencephalographical effects of MK 940.
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:7

    Topics: Adjustment Disorders; Adult; Amitriptyline; Anorexia Nervosa; Attention; Clinical Trials as Topic; C

1970

Other Studies

9 other studies available for amitriptyline and Nausea

ArticleYear
Amitriptyline for post-COVID headache: effectiveness, tolerability, and response predictors.
    Journal of neurology, 2022, Volume: 269, Issue:11

    Topics: Amitriptyline; COVID-19; Female; Headache; Humans; Male; Migraine Disorders; Nausea; Retrospective S

2022
Lessons learned from hospice care.
    The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists, 2013, Volume: 28, Issue:10

    Topics: Aged; Aged, 80 and over; Amitriptyline; Analgesics, Opioid; Drug Monitoring; Fentanyl; Health Servic

2013
Cyclic vomiting syndrome in adults.
    Wiener medizinische Wochenschrift (1946), 2013, Volume: 163, Issue:21-22

    Topics: Abdominal Pain; Adult; Amitriptyline; Antiemetics; Combined Modality Therapy; Diagnosis, Differentia

2013
Chronic idiopathic nausea of childhood.
    The Journal of pediatrics, 2014, Volume: 164, Issue:5

    Topics: Abdominal Pain; Adolescent; Amitriptyline; Antidepressive Agents, Tricyclic; Anxiety; Child; Chronic

2014
Cyclic vomiting syndrome in Taiwanese children.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2011, Volume: 110, Issue:1

    Topics: Adolescent; Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Age of Onset; Amitriptyline;

2011
[AMITRIPTYLINE IN AMBULATORY PSYCHIATRIC PRACTICE].
    L' Ospedale maggiore, 1964, Volume: 59

    Topics: Amitriptyline; Autonomic Nervous System Diseases; Depression; Drug Eruptions; Drug Hypersensitivity;

1964
Withdrawal symptoms after abrupt cessation of amitriptyline in an eight-year-old boy.
    The American journal of psychiatry, 1979, Volume: 136, Issue:4A

    Topics: Amitriptyline; Child; Humans; Hyperkinesis; Male; Nausea; Substance Withdrawal Syndrome

1979
Progressive loss of antiemetic efficacy during subsequent courses of chemotherapy.
    European journal of cancer (Oxford, England : 1990), 1992, Volume: 28, Issue:2-3

    Topics: Adult; Aged; Amitriptyline; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Cyclophosph

1992
L-dopa and tricyclic antidepressants in affective disorders. A pilot study.
    Activitas nervosa superior, 1974, Volume: 16, Issue:3

    Topics: Adult; Amitriptyline; Depression; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Levodo

1974