amitriptyline has been researched along with Narcolepsy in 2 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Narcolepsy: A condition characterized by recurrent episodes of daytime somnolence and lapses in consciousness (microsomnias) that may be associated with automatic behaviors and AMNESIA. CATAPLEXY; SLEEP PARALYSIS, and hypnagogic HALLUCINATIONS frequently accompany narcolepsy. The pathophysiology of this disorder includes sleep-onset rapid eye movement (REM) sleep, which normally follows stage III or IV sleep. (From Neurology 1998 Feb;50(2 Suppl 1):S2-S7)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ferini-Strambi, L | 1 |
| Oldani, A | 1 |
| Zucconi, M | 1 |
| Castronovo, V | 1 |
| Montorsi, F | 1 |
| Rigatti, P | 1 |
| Smirne, S | 1 |
| Ullman, KC | 1 |
2 other studies available for amitriptyline and Narcolepsy
| Article | Year |
|---|---|
Sleep-related painful erections: clinical and polysomnographic features.
Topics: Adrenergic beta-Antagonists; Adult; Amitriptyline; Humans; Lorazepam; Male; Middle Aged; Narcolepsy; | 1996 |
Narcolepsy and schizophrenia.
Topics: Amitriptyline; Dextroamphetamine; Humans; Male; Middle Aged; Narcolepsy; Schizophrenia | 1977 |