amitriptyline has been researched along with Myotonic Dystrophy in 1 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Myotonic Dystrophy: Neuromuscular disorder characterized by PROGRESSIVE MUSCULAR ATROPHY; MYOTONIA, and various multisystem atrophies. Mild INTELLECTUAL DISABILITY may also occur. Abnormal TRINUCLEOTIDE REPEAT EXPANSION in the 3' UNTRANSLATED REGIONS of DMPK PROTEIN gene is associated with Myotonic Dystrophy 1. DNA REPEAT EXPANSION of zinc finger protein-9 gene intron is associated with Myotonic Dystrophy 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to quantify the degree of muscle weakness and myotonia in 12 patients with myotonic dystrophy (MD), and to quantitatively determine the effects of a four- to six-month therapeutic trial of amitriptyline." | 7.68 | Myotonic dystrophy: quantification of muscle weakness and myotonia and the effect of amitriptyline and exercise. ( Miller, RG; Milner-Brown, HS, 1990) |
| "The purpose of this study was to quantify the degree of muscle weakness and myotonia in 12 patients with myotonic dystrophy (MD), and to quantitatively determine the effects of a four- to six-month therapeutic trial of amitriptyline." | 3.68 | Myotonic dystrophy: quantification of muscle weakness and myotonia and the effect of amitriptyline and exercise. ( Miller, RG; Milner-Brown, HS, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Milner-Brown, HS | 1 |
| Miller, RG | 1 |
1 other study available for amitriptyline and Myotonic Dystrophy
| Article | Year |
|---|---|
Myotonic dystrophy: quantification of muscle weakness and myotonia and the effect of amitriptyline and exercise.
Topics: Action Potentials; Adult; Amitriptyline; Arrhythmias, Cardiac; Exercise Therapy; Female; Humans; Mal | 1990 |