amitriptyline has been researched along with Myocardial Ischemia in 3 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
| Excerpt | Relevance | Reference |
|---|---|---|
| " The present study was undertaken to compare the effects of amitriptyline and mianserin with those of tianeptine, an atypical tricyclic antidepressant drug, in rat isolated working heart subjected to a local myocardial ischemia." | 3.68 | Absence of relationship between antiarrhythmic effects of antidepressant drugs and lipid peroxidation. ( Abadie, C; Ben Baouali, A; Bril, A; Maupoil, V; Rochette, L, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fedorets, VN | 1 |
| Azkárate Egaña, I | 1 |
| Luque Lezcano, O | 1 |
| Lara Bocero, G | 1 |
| Cabarcos Grávalos, E | 1 |
| Bril, A | 1 |
| Abadie, C | 1 |
| Ben Baouali, A | 1 |
| Maupoil, V | 1 |
| Rochette, L | 1 |
3 other studies available for amitriptyline and Myocardial Ischemia
| Article | Year |
|---|---|
[Characteristics of clinical and pharmacological efficacy of tranquilizers and antidepressants in patients with ischemic heart disease and type A behavior].
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Behavior; Benzodiazepines; Female; Hum | 2004 |
[Electrocardiographic alterations mimicking ischemic heart disease in a patient with tricyclic antidepressive poisoning].
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Diagnosis, Differential; Electrocardiography | 2007 |
Absence of relationship between antiarrhythmic effects of antidepressant drugs and lipid peroxidation.
Topics: Amitriptyline; Animals; Anti-Arrhythmia Agents; Antidepressive Agents, Tricyclic; Brain; Cardiac Out | 1993 |