amitriptyline has been researched along with Muscle Spasticity in 5 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Muscle Spasticity: A form of muscle hypertonia associated with upper MOTOR NEURON DISEASE. Resistance to passive stretch of a spastic muscle results in minimal initial resistance (a free interval) followed by an incremental increase in muscle tone. Tone increases in proportion to the velocity of stretch. Spasticity is usually accompanied by HYPERREFLEXIA and variable degrees of MUSCLE WEAKNESS. (From Adams et al., Principles of Neurology, 6th ed, p54)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is a neurodegenerative disorder characterized by late-infantile onset spastic ataxia and other neurological features." | 1.37 | Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS): typical clinical and neuroimaging features in a Brazilian family. ( Abdala, N; Abdalla, C; Abrahão, A; Barsottini, OG; Braga-Neto, P; Pedroso, JL; Rivero, RL, 2011) |
| "Fifty-seven cases of spastic torticollis are reported, and its etiologic factors, including stressful situations, are analyzed." | 1.28 | [Spastic torticollis]. ( Kolesova, OE; Oboĭmov, EI, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pedroso, JL | 1 |
| Braga-Neto, P | 1 |
| Abrahão, A | 1 |
| Rivero, RL | 1 |
| Abdalla, C | 1 |
| Abdala, N | 1 |
| Barsottini, OG | 1 |
| Fisk, JW | 1 |
| Brown, BR | 1 |
| Womble, J | 1 |
| Basmajian, JV | 1 |
| Oboĭmov, EI | 1 |
| Kolesova, OE | 1 |
2 trials available for amitriptyline and Muscle Spasticity
| Article | Year |
|---|---|
Cyclobenzaprine in intractable pain syndromes with muscle spasm.
Topics: Adult; Amitriptyline; Clinical Trials as Topic; Diazepam; Dibenzocycloheptenes; Female; Humans; Male | 1978 |
Cyclobenzaprine hydrochloride effect on skeletal muscle spasm in the lumbar region and neck: two double-blind controlled clinical and laboratory studies.
Topics: Administration, Oral; Amitriptyline; Computers; Dibenzocycloheptenes; Double-Blind Method; Drug Eval | 1978 |
3 other studies available for amitriptyline and Muscle Spasticity
| Article | Year |
|---|---|
Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS): typical clinical and neuroimaging features in a Brazilian family.
Topics: Adult; Amitriptyline; Baclofen; Female; Humans; Magnetic Resonance Imaging; Male; Muscle Relaxants, | 2011 |
Fibromyalgia.
Topics: Acupuncture Therapy; Amitriptyline; Humans; Muscle Spasticity; Muscular Diseases; Pain Management | 1982 |
[Spastic torticollis].
Topics: Amitriptyline; Drug Therapy, Combination; Female; Humans; Male; Muscle Spasticity; Neck Muscles; Ser | 1989 |