Page last updated: 2024-10-22

amitriptyline and Muscle Rigidity

amitriptyline has been researched along with Muscle Rigidity in 1 studies

Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.

Muscle Rigidity: Continuous involuntary sustained muscle contraction which is often a manifestation of BASAL GANGLIA DISEASES. When an affected muscle is passively stretched, the degree of resistance remains constant regardless of the rate at which the muscle is stretched. This feature helps to distinguish rigidity from MUSCLE SPASTICITY. (From Adams et al., Principles of Neurology, 6th ed, p73)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Share, NN1
McFarlane, CS1

Other Studies

1 other study available for amitriptyline and Muscle Rigidity

ArticleYear
Cyclobenzaprine: novel centrally acting skeletal muscle relaxant.
    Neuropharmacology, 1975, Volume: 14, Issue:9

    Topics: Amitriptyline; Animals; Anticonvulsants; Ataxia; Cats; Chlorpromazine; Decerebrate State; Diazepam;

1975