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amitriptyline and Muscle Relaxation

amitriptyline has been researched along with Muscle Relaxation in 7 studies

Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.

Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.

Research Excerpts

ExcerptRelevanceReference
"Cats presenting with obstructive acute renal failure (ARF) received amitriptyline, and renal function and survival rates were analyzed."5.32Amitriptyline eliminates calculi through urinary tract smooth muscle relaxation. ( Achar, E; Achar, RA; Campos, AH; Paiva, TB; Schor, N, 2003)
"These results indicate that amitriptyline and nortriptyline could act as adrenoceptor antagonists and direct inhibitors of smooth muscle contraction of human mesenteric arteries, whereas sertraline might principally exert its action only as direct inhibitor of smooth muscle contraction."3.70Relaxant effects of antidepressants on human isolated mesenteric arteries. ( Flor, B; Lluch, P; Lluch, S; Medina, P; Pallardó, F; Segarra, G; Vila, JM, 1999)
"Cats presenting with obstructive acute renal failure (ARF) received amitriptyline, and renal function and survival rates were analyzed."1.32Amitriptyline eliminates calculi through urinary tract smooth muscle relaxation. ( Achar, E; Achar, RA; Campos, AH; Paiva, TB; Schor, N, 2003)
"Xylamine (10 microM) was without effect."1.29Inhibitory effect of noradrenaline uptake inhibitors on contractions of rat aortic smooth muscle. ( Huang, Y, 1996)
"Pentobarbital and Sulpiride produce a biphasyc effect of opposite sign: at small doses Pentobarbital increases the stretch response while Sulpiride reduces it."1.26[Action of some psychotropic drugs on the electrmyographic response evoked by stretches of the gastrocnemius muscle of rats submitted to stress]. ( Eandi, M; Ricci Gamalero, S; Taglia, P, 1980)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's2 (28.57)18.2507
2000's2 (28.57)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Achar, E1
Achar, RA1
Paiva, TB1
Campos, AH1
Schor, N1
Share, NN1
Eandi, M1
Ricci Gamalero, S1
Taglia, P1
Huang, Y1
Vila, JM1
Medina, P1
Segarra, G1
Lluch, P1
Pallardó, F1
Flor, B1
Lluch, S1
Irman-Florjanc, T1
Kuzner, J1
Drevensek, G1
Budihna, MV1
Ueki, S1
Fujiwara, M1
Inoue, K1

Other Studies

7 other studies available for amitriptyline and Muscle Relaxation

ArticleYear
Amitriptyline eliminates calculi through urinary tract smooth muscle relaxation.
    Kidney international, 2003, Volume: 64, Issue:4

    Topics: Acute Kidney Injury; Amitriptyline; Animals; Cats; Humans; In Vitro Techniques; Male; Muscle Relaxat

2003
Cyclobenzaprine: studies on its site of muscle relaxant action in the cat.
    Neuropharmacology, 1980, Volume: 19, Issue:8

    Topics: Amitriptyline; Animals; Brain Stem; Cats; Decerebrate State; Dose-Response Relationship, Drug; Muscl

1980
[Action of some psychotropic drugs on the electrmyographic response evoked by stretches of the gastrocnemius muscle of rats submitted to stress].
    Bollettino della Societa italiana di biologia sperimentale, 1980, Jun-30, Volume: 56, Issue:12

    Topics: Amitriptyline; Animals; Chlorpromazine; Dextroamphetamine; Meprobamate; Muscle Contraction; Muscle R

1980
Inhibitory effect of noradrenaline uptake inhibitors on contractions of rat aortic smooth muscle.
    British journal of pharmacology, 1996, Volume: 117, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Amitriptyline; Animals; Aorta, Thoracic; Calcium; Endothelin-1; Endoth

1996
Relaxant effects of antidepressants on human isolated mesenteric arteries.
    British journal of clinical pharmacology, 1999, Volume: 48, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Amitriptyline; Antidepressive Agents; Antidepressive Agents, Second-

1999
Amitriptyline and citalopram, two different types of antidepressant drugs, relax histamine-contracted porcine coronary artery.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2002, Volume: 51 Suppl 1

    Topics: Amitriptyline; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Citalopram; Coronar

2002
[Behavioral pharmacology of a new antidepressant, lopramine].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1976, Volume: 72, Issue:5

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Apomorphine; Avoidance Learning; Blepharop

1976