amitriptyline has been researched along with Multiple Sclerosis, Relapsing-Remitting in 1 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Multiple Sclerosis, Relapsing-Remitting: The most common clinical variant of MULTIPLE SCLEROSIS, characterized by recurrent acute exacerbations of neurologic dysfunction followed by partial or complete recovery. Common clinical manifestations include loss of visual (see OPTIC NEURITIS), motor, sensory, or bladder function. Acute episodes of demyelination may occur at any site in the central nervous system, and commonly involve the optic nerves, spinal cord, brain stem, and cerebellum. (Adams et al., Principles of Neurology, 6th ed, pp903-914)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We describe an MS patient who developed migraine headaches, which followed a specific pattern coincident with interferon-beta administration." | 1.33 | Migraines linked to interferon-beta treatment of multiple sclerosis. ( Fast, A; Khromov, A; Nissinoff, J; Segal, M, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Khromov, A | 1 |
| Segal, M | 1 |
| Nissinoff, J | 1 |
| Fast, A | 1 |
1 other study available for amitriptyline and Multiple Sclerosis, Relapsing-Remitting
| Article | Year |
|---|---|
Migraines linked to interferon-beta treatment of multiple sclerosis.
Topics: Adult; Amitriptyline; Analgesics, Non-Narcotic; Female; Humans; Interferon-beta; Migraine Disorders; | 2005 |