amitriptyline has been researched along with Morphine Dependence in 6 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Morphine Dependence: Strong dependence, both physiological and emotional, upon morphine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Morphine dependency was induced using the oral method, and then, amitriptyline-induced antinociceptive effects were measured at 4 doses (2." | 5.48 | The effect of amitriptyline administration on pain-related behaviors in morphine-dependent rats: Hypoalgesia or hyperalgesia? ( Akbari, E; Haghparast, A; Mirzaei, E; Rezaee, L; Zarrabian, S, 2018) |
| "Morphine dependency was induced using the oral method, and then, amitriptyline-induced antinociceptive effects were measured at 4 doses (2." | 1.48 | The effect of amitriptyline administration on pain-related behaviors in morphine-dependent rats: Hypoalgesia or hyperalgesia? ( Akbari, E; Haghparast, A; Mirzaei, E; Rezaee, L; Zarrabian, S, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Akbari, E | 1 |
| Mirzaei, E | 1 |
| Rezaee, L | 1 |
| Zarrabian, S | 1 |
| Haghparast, A | 1 |
| Habibi-Asl, B | 1 |
| Vaez, H | 1 |
| Najafi, M | 1 |
| Bidaghi, A | 1 |
| Ghanbarzadeh, S | 1 |
| Schürks, M | 1 |
| Overlack, M | 1 |
| Bonnet, U | 1 |
| Tai, YH | 1 |
| Wang, YH | 1 |
| Wang, JJ | 1 |
| Tao, PL | 1 |
| Tung, CS | 1 |
| Wong, CS | 1 |
| Kamei, C | 1 |
| Shimomura, K | 1 |
| Ueki, S | 1 |
| Hasse, HE | 1 |
| Schiefgen, W | 1 |
| Schönhöfer, P | 1 |
6 other studies available for amitriptyline and Morphine Dependence
| Article | Year |
|---|---|
The effect of amitriptyline administration on pain-related behaviors in morphine-dependent rats: Hypoalgesia or hyperalgesia?
Topics: Amitriptyline; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Dose-Response Relationship, Dr | 2018 |
Attenuation of morphine-induced dependence and tolerance by ceftriaxone and amitriptyline in mice.
Topics: Amitriptyline; Animals; Ceftriaxone; Drug Tolerance; Male; Mice; Morphine; Morphine Dependence | 2014 |
Naltrexone treatment of combined alcohol and opioid dependence: deterioration of co-morbid major depression.
Topics: Alcoholism; Amitriptyline; Depressive Disorder, Major; Ethanol; Humans; Male; Middle Aged; Morphine; | 2005 |
Amitriptyline suppresses neuroinflammation and up-regulates glutamate transporters in morphine-tolerant rats.
Topics: Amino Acid Transport System X-AG; Amitriptyline; Analgesics, Non-Narcotic; Animals; Behavior, Animal | 2006 |
Significance of withdrawal jumping response in predicting physical dependence in mice.
Topics: Amitriptyline; Animals; Atropine; Cannabis; Chlordiazepoxide; Chlorpromazine; Diazepam; Humans; Imip | 1973 |
[Emergencies in drugged adolescents].
Topics: Adolescent; Amitriptyline; Benzazepines; Cannabis; Emergencies; Hallucinogens; Humans; Male; Morphin | 1972 |