amitriptyline has been researched along with Melanoma in 2 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (50.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (50.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Parker, KA | 1 |
Glaysher, S | 1 |
Hurren, J | 1 |
Knight, LA | 1 |
McCormick, D | 1 |
Suovouri, A | 1 |
Amberger-Murphy, V | 1 |
Pilkington, GJ | 1 |
Cree, IA | 1 |
Khouzam, HR | 1 |
Emery, PE | 1 |
Reaves, B | 1 |
2 other studies available for amitriptyline and Melanoma
Article | Year |
---|---|
The effect of tricyclic antidepressants on cutaneous melanoma cell lines and primary cell cultures.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Cell Line, Tumor; Clomipramine; Dose-Response Relat | 2012 |
Secondary mania in late life.
Topics: Age Factors; Aged; Amitriptyline; Bipolar Disorder; Brain Neoplasms; Diagnosis, Differential; Female | 1994 |