Page last updated: 2024-10-22

amitriptyline and Melanoma

amitriptyline has been researched along with Melanoma in 2 studies

Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.

Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Parker, KA1
Glaysher, S1
Hurren, J1
Knight, LA1
McCormick, D1
Suovouri, A1
Amberger-Murphy, V1
Pilkington, GJ1
Cree, IA1
Khouzam, HR1
Emery, PE1
Reaves, B1

Other Studies

2 other studies available for amitriptyline and Melanoma

ArticleYear
The effect of tricyclic antidepressants on cutaneous melanoma cell lines and primary cell cultures.
    Anti-cancer drugs, 2012, Volume: 23, Issue:1

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Cell Line, Tumor; Clomipramine; Dose-Response Relat

2012
Secondary mania in late life.
    Journal of the American Geriatrics Society, 1994, Volume: 42, Issue:1

    Topics: Age Factors; Aged; Amitriptyline; Bipolar Disorder; Brain Neoplasms; Diagnosis, Differential; Female

1994