amitriptyline has been researched along with Malaria in 1 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The present experiments explored whether the sphingomyelinase inhibitor amitriptyline or genetic knockout of host acid sphingomyelinase influence in vitro parasite growth, eryptosis of Plasmodium falciparum-infected human erythrocytes, in vivo parasitemia and survival of P." | 7.74 | Influence of amitriptyline on eryptosis, parasitemia and survival of Plasmodium berghei-infected mice. ( Brand, V; Gulbins, E; Huber, SM; Jendrossek, V; Koka, S; Lang, C; Lang, F, 2008) |
| " The present experiments explored whether the sphingomyelinase inhibitor amitriptyline or genetic knockout of host acid sphingomyelinase influence in vitro parasite growth, eryptosis of Plasmodium falciparum-infected human erythrocytes, in vivo parasitemia and survival of P." | 3.74 | Influence of amitriptyline on eryptosis, parasitemia and survival of Plasmodium berghei-infected mice. ( Brand, V; Gulbins, E; Huber, SM; Jendrossek, V; Koka, S; Lang, C; Lang, F, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brand, V | 1 |
| Koka, S | 1 |
| Lang, C | 1 |
| Jendrossek, V | 1 |
| Huber, SM | 1 |
| Gulbins, E | 1 |
| Lang, F | 1 |
1 other study available for amitriptyline and Malaria
| Article | Year |
|---|---|
Influence of amitriptyline on eryptosis, parasitemia and survival of Plasmodium berghei-infected mice.
Topics: Amitriptyline; Animals; Apoptosis; Ceramides; Erythrocytes; Female; Humans; Malaria; Male; Mice; Par | 2008 |