amitriptyline has been researched along with Lung Neoplasms in 4 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Lung Neoplasms: Tumors or cancer of the LUNG.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gemcitabine is a nucleosid analog approved for use in the treatment of metastatic urothelial carcinoma of the bladder." | 1.32 | Gemcitabine-associated scleroderma-like changes of the lower extremities. ( Bessis, D; Guilhou, JJ; Guillot, B; Legouffe, E, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zinnah, KMA | 1 |
| Park, SY | 1 |
| Ortiz, T | 1 |
| Villanueva-Paz, M | 1 |
| Díaz-Parrado, E | 1 |
| Illanes, M | 2 |
| Fernández-Rodríguez, A | 1 |
| Sánchez-Alcázar, JA | 2 |
| de Miguel, M | 2 |
| Cordero, MD | 1 |
| Bautista-Ferrufino, MR | 1 |
| Carmona-López, MI | 1 |
| Ríos, MJ | 1 |
| Garrido-Maraver, J | 1 |
| Alcudia, A | 1 |
| Navas, P | 1 |
| Bessis, D | 1 |
| Guillot, B | 1 |
| Legouffe, E | 1 |
| Guilhou, JJ | 1 |
4 other studies available for amitriptyline and Lung Neoplasms
| Article | Year |
|---|---|
Sensitizing TRAIL‑resistant A549 lung cancer cells and enhancing TRAIL‑induced apoptosis with the antidepressant amitriptyline.
Topics: A549 Cells; Amitriptyline; Autophagy; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chloroqui | 2021 |
Amitriptyline down-regulates coenzyme Q
Topics: Amitriptyline; Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; Kinetics; Lung Neoplasms; | 2017 |
Acute oxidant damage promoted on cancer cells by amitriptyline in comparison with some common chemotherapeutic drugs.
Topics: Amitriptyline; Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Carcinoma, Non- | 2010 |
Gemcitabine-associated scleroderma-like changes of the lower extremities.
Topics: Acetaminophen; Amitriptyline; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy | 2004 |