Page last updated: 2024-10-22

amitriptyline and Low Back Ache

amitriptyline has been researched along with Low Back Ache in 28 studies

Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.

Research Excerpts

ExcerptRelevanceReference
"This trial suggests that amitriptyline may be an effective treatment for chronic low back pain."9.27Efficacy of Low-Dose Amitriptyline for Chronic Low Back Pain: A Randomized Clinical Trial. ( Arnold, C; Cicuttini, FM; Fong, C; Forbes, A; Gibson, SJ; Heritier, S; Sim, MR; Urquhart, DM; van Tulder, M; Wang, Y; Wluka, AE, 2018)
"Clinical Question Does the addition of cyclobenzaprine or oxycodone with acetaminophen to naproxen result in improved functional outcomes at one week when compared to placebo in patients with acute low back pain? Article Chosen Friedman B, Dym A, Davitt, M, et al."9.22Comparison of naproxen with cyclobenzaprine, oxycodone-acetaminophen, and placebo for the treatment of acute low back pain. ( Gottlieb, M; Njie, A, 2016)
"To evaluate efficacy and tolerability of once-daily cyclobenzaprine extended release (CER) 15- and 30-mg capsules in patients with muscle spasm associated with acute, painful musculoskeletal conditions."9.14Cyclobenzaprine ER for muscle spasm associated with low back and neck pain: two randomized, double-blind, placebo-controlled studies of identical design. ( Altman, CA; Borenstein, DG; Malanga, GA; Ruoff, GE; Weil, AJ; Xie, F, 2009)
"Low back pain is a major clinical and public health problem, with limited evidence-based treatments."6.82Is low-dose amitriptyline effective in the management of chronic low back pain? Study protocol for a randomised controlled trial. ( Anthony, SN; Arnold, C; Cicuttini, FM; Fong, C; Forbes, A; Gibson, SJ; Sim, MR; Urquhart, DM; van Tulder, M; Wluka, AE, 2016)
"Cyclobenzaprine hydrochloride has the most recent and largest clinical trials demonstrating its benefit, but carisoprodol and metaxalone also appear to be effective."6.42Commonly used muscle relaxant therapies for acute low back pain: a review of carisoprodol, cyclobenzaprine hydrochloride, and metaxalone. ( Toth, PP; Urtis, J, 2004)
"This trial suggests that amitriptyline may be an effective treatment for chronic low back pain."5.27Efficacy of Low-Dose Amitriptyline for Chronic Low Back Pain: A Randomized Clinical Trial. ( Arnold, C; Cicuttini, FM; Fong, C; Forbes, A; Gibson, SJ; Heritier, S; Sim, MR; Urquhart, DM; van Tulder, M; Wang, Y; Wluka, AE, 2018)
"Clinical Question Does the addition of cyclobenzaprine or oxycodone with acetaminophen to naproxen result in improved functional outcomes at one week when compared to placebo in patients with acute low back pain? Article Chosen Friedman B, Dym A, Davitt, M, et al."5.22Comparison of naproxen with cyclobenzaprine, oxycodone-acetaminophen, and placebo for the treatment of acute low back pain. ( Gottlieb, M; Njie, A, 2016)
"To evaluate efficacy and tolerability of once-daily cyclobenzaprine extended release (CER) 15- and 30-mg capsules in patients with muscle spasm associated with acute, painful musculoskeletal conditions."5.14Cyclobenzaprine ER for muscle spasm associated with low back and neck pain: two randomized, double-blind, placebo-controlled studies of identical design. ( Altman, CA; Borenstein, DG; Malanga, GA; Ruoff, GE; Weil, AJ; Xie, F, 2009)
"The role of amitriptyline in musculoskeletal pain is not as clearly defined as in classical neuropathic pain conditions."4.95Amitriptyline for musculoskeletal complaints: a systematic review. ( Bierma-Zeinstra, SMA; Bindels, PJE; Schiphof, D; van den Driest, JJ, 2017)
"Adding cyclobenzaprine or oxycodone/acetaminophen to naproxen for the treatment of acute low back pain does nothing more than increase adverse effects."3.83PURLs: More isn't better with acute low back pain treatment. ( Frazer, K; Stevermer, JJ, 2016)
"Low back pain is a major clinical and public health problem, with limited evidence-based treatments."2.82Is low-dose amitriptyline effective in the management of chronic low back pain? Study protocol for a randomised controlled trial. ( Anthony, SN; Arnold, C; Cicuttini, FM; Fong, C; Forbes, A; Gibson, SJ; Sim, MR; Urquhart, DM; van Tulder, M; Wluka, AE, 2016)
"Cyclobenzaprine hydrochloride has the most recent and largest clinical trials demonstrating its benefit, but carisoprodol and metaxalone also appear to be effective."2.42Commonly used muscle relaxant therapies for acute low back pain: a review of carisoprodol, cyclobenzaprine hydrochloride, and metaxalone. ( Toth, PP; Urtis, J, 2004)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (25.00)29.6817
2010's17 (60.71)24.3611
2020's4 (14.29)2.80

Authors

AuthorsStudies
O'Neal, M1
Alwan, R1
Schwartz, M1
Fischer, LM1
Bläute, C1
Stork, J1
Colloca, L1
Zöllner, C1
Klinger, R1
Khong, TK1
Lall, K1
Urquhart, DM4
Wluka, AE3
Heritier, S2
Fong, C3
Wang, Y2
Cicuttini, FM3
van den Driest, JJ1
Bierma-Zeinstra, SMA1
Bindels, PJE1
Schiphof, D1
van Tulder, M2
Forbes, A2
Sim, MR2
Gibson, SJ2
Arnold, C2
Kalita, J2
Misra, UK2
Lin, CC1
McLachlan, AJ1
Maher, CG1
Wluka, A1
Cicuttini, F1
Kohat, AK1
Bhoi, SK1
Friedman, BW1
Dym, AA1
Davitt, M1
Holden, L1
Solorzano, C1
Esses, D1
Bijur, PE1
Gallagher, EJ1
Pi, ZB1
Lin, H1
He, GD1
Cai, Z1
Xu, XZ1
Carpenter, CR1
Chaffee, DM1
Frazer, K1
Stevermer, JJ1
Schneider, BJ1
Kennedy, DJ1
Kumbhare, D1
Gottlieb, M1
Njie, A1
Anthony, SN1
Malanga, GA1
Ruoff, GE1
Weil, AJ1
Altman, CA1
Xie, F1
Borenstein, DG1
Orbai, AM1
Meyerhoff, JO1
Maigne, JY1
Pigeau, I1
Aguer, N1
Doursounian, L1
Chatellier, G1
Wielage, R1
Bansal, M1
Wilson, K1
Klein, R1
Happich, M1
Toth, PP1
Urtis, J1
George, R1
Poonnoose, P1
Isaiah, R1
Meyer, MA1
Vas, J1
Perea-Milla, E1
Mendez, C1
Silva, LC1
Herrera Galante, A1
Aranda Regules, JM1
Martinez Barquin, DM1
Aguilar, I1
Faus, V1
Schreiber, S1
Vinokur, S1
Shavelzon, V1
Pick, CG1
Zahavi, E1
Shir, Y1
Harwood, MI1
Chang, SI1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of Ketoprofen Gel to Placebo in Patients Presented With Mechanical Low Back Pain to the Emergency Department: A Randomized Placebo Controlled Trial[NCT02619695]Phase 4160 participants (Anticipated)Interventional2015-06-30Recruiting
"Interest of the Return to Primary Care of the Low Back Booklet of Health Insurance in the Recovery of Common Acute Low Back Pain"[NCT03953625]33 participants (Actual)Interventional2018-11-29Completed
A Randomized Three-armed Comparative Effectiveness Study of Various Medications for Musculoskeletal Low Back Pain: Defining the Added Benefit of Muscle Relaxants and Opioids.[NCT01587274]Phase 4323 participants (Actual)Interventional2012-04-30Completed
Achieving Peri-Operative Pain Control Without Opioids[NCT04813991]Phase 30 participants (Actual)Interventional2022-03-15Withdrawn (stopped due to Enrollment was never initiated and the PI is leaving the institution so the study is closing.)
Aromatherapy for Management of Back Pain in the Emergency Department[NCT03377088]60 participants (Anticipated)Interventional2017-12-11Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in Functional Disability as Measured by the Roland Morris Disability Questionnaire

"The Roland Morris Disability Questionnaire (RMDQ) is a 24 item instrument that evaluates the impact of low back pain on one's daily life. It is most sensitive for patients with mild to moderate disability due to acute, sub-acute or chronic low back pain. Each question can be answered as either a yes or no. The score ranges from 0 to 24 where a higher score reflects greater impairment and, therefore, worsening in the quality of life. The change in RMDQ is obtained by subtracting the RMDQ score at one week after discharge from the baseline score." (NCT01587274)
Timeframe: Baseline and one week after discharge from emergency department

Interventionunits on a scale (Median)
Opioid5
Skeletal Muscle Relaxant4
Naproxen Alone7

Reviews

5 reviews available for amitriptyline and Low Back Ache

ArticleYear
Amitriptyline for musculoskeletal complaints: a systematic review.
    Family practice, 2017, 04-01, Volume: 34, Issue:2

    Topics: Amitriptyline; Analgesics, Non-Narcotic; Arthritis, Rheumatoid; Humans; Low Back Pain; Musculoskelet

2017
Cyclobenzaprine in the Treatment of Low Back Pain.
    American family physician, 2016, Feb-01, Volume: 93, Issue:3

    Topics: Amitriptyline; Humans; Low Back Pain; Muscle Relaxants, Central

2016
Cost-effectiveness of duloxetine in chronic low back pain: a Quebec societal perspective.
    Spine, 2013, May-15, Volume: 38, Issue:11

    Topics: Age Factors; Aged; Amitriptyline; Analgesics; Cardiovascular Diseases; Celecoxib; Chronic Disease; C

2013
Commonly used muscle relaxant therapies for acute low back pain: a review of carisoprodol, cyclobenzaprine hydrochloride, and metaxalone.
    Clinical therapeutics, 2004, Volume: 26, Issue:9

    Topics: Amitriptyline; Carisoprodol; Humans; Low Back Pain; Muscle Relaxants, Central; Oxazolidinones; Rando

2004
Clinical inquiries. What is the most effective treatment for acute low back pain?
    The Journal of family practice, 2002, Volume: 51, Issue:2

    Topics: Acetaminophen; Adrenal Cortex Hormones; Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; Bed

2002

Trials

9 trials available for amitriptyline and Low Back Ache

ArticleYear
Observing treatment outcomes in other patients can elicit augmented placebo effects on pain treatment: a double-blinded randomized clinical trial with patients with chronic low back pain.
    Pain, 2022, 07-01, Volume: 163, Issue:7

    Topics: Amitriptyline; Chronic Pain; Humans; Low Back Pain; Male; Pain Measurement; Placebo Effect; Treatmen

2022
Efficacy of Low-Dose Amitriptyline for Chronic Low Back Pain: A Randomized Clinical Trial.
    JAMA internal medicine, 2018, 11-01, Volume: 178, Issue:11

    Topics: Adult; Aged; Amitriptyline; Analgesics, Non-Narcotic; Chronic Pain; Double-Blind Method; Female; Hum

2018
An open labeled randomized controlled trial of pregabalin versus amitriptyline in chronic low backache.
    Journal of the neurological sciences, 2014, Jul-15, Volume: 342, Issue:1-2

    Topics: Adolescent; Adult; Aged; Amitriptyline; Analgesics, Non-Narcotic; Chronic Disease; Disability Evalua

2014
Naproxen With Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo for Treating Acute Low Back Pain: A Randomized Clinical Trial.
    JAMA, 2015, Oct-20, Volume: 314, Issue:15

    Topics: Acetaminophen; Acute Disease; Adult; Aged; Amitriptyline; Analgesics, Opioid; Anti-Inflammatory Agen

2015
Naproxen With Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo for Treating Acute Low Back Pain: A Randomized Clinical Trial.
    JAMA, 2015, Oct-20, Volume: 314, Issue:15

    Topics: Acetaminophen; Acute Disease; Adult; Aged; Amitriptyline; Analgesics, Opioid; Anti-Inflammatory Agen

2015
Naproxen With Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo for Treating Acute Low Back Pain: A Randomized Clinical Trial.
    JAMA, 2015, Oct-20, Volume: 314, Issue:15

    Topics: Acetaminophen; Acute Disease; Adult; Aged; Amitriptyline; Analgesics, Opioid; Anti-Inflammatory Agen

2015
Naproxen With Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo for Treating Acute Low Back Pain: A Randomized Clinical Trial.
    JAMA, 2015, Oct-20, Volume: 314, Issue:15

    Topics: Acetaminophen; Acute Disease; Adult; Aged; Amitriptyline; Analgesics, Opioid; Anti-Inflammatory Agen

2015
Naproxen With Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo for Treating Acute Low Back Pain: A Randomized Clinical Trial.
    JAMA, 2015, Oct-20, Volume: 314, Issue:15

    Topics: Acetaminophen; Acute Disease; Adult; Aged; Amitriptyline; Analgesics, Opioid; Anti-Inflammatory Agen

2015
Naproxen With Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo for Treating Acute Low Back Pain: A Randomized Clinical Trial.
    JAMA, 2015, Oct-20, Volume: 314, Issue:15

    Topics: Acetaminophen; Acute Disease; Adult; Aged; Amitriptyline; Analgesics, Opioid; Anti-Inflammatory Agen

2015
Naproxen With Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo for Treating Acute Low Back Pain: A Randomized Clinical Trial.
    JAMA, 2015, Oct-20, Volume: 314, Issue:15

    Topics: Acetaminophen; Acute Disease; Adult; Aged; Amitriptyline; Analgesics, Opioid; Anti-Inflammatory Agen

2015
Naproxen With Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo for Treating Acute Low Back Pain: A Randomized Clinical Trial.
    JAMA, 2015, Oct-20, Volume: 314, Issue:15

    Topics: Acetaminophen; Acute Disease; Adult; Aged; Amitriptyline; Analgesics, Opioid; Anti-Inflammatory Agen

2015
Naproxen With Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo for Treating Acute Low Back Pain: A Randomized Clinical Trial.
    JAMA, 2015, Oct-20, Volume: 314, Issue:15

    Topics: Acetaminophen; Acute Disease; Adult; Aged; Amitriptyline; Analgesics, Opioid; Anti-Inflammatory Agen

2015
Naproxen With Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo for Treating Acute Low Back Pain: A Randomized Clinical Trial.
    JAMA, 2015, Oct-20, Volume: 314, Issue:15

    Topics: Acetaminophen; Acute Disease; Adult; Aged; Amitriptyline; Analgesics, Opioid; Anti-Inflammatory Agen

2015
Naproxen With Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo for Treating Acute Low Back Pain: A Randomized Clinical Trial.
    JAMA, 2015, Oct-20, Volume: 314, Issue:15

    Topics: Acetaminophen; Acute Disease; Adult; Aged; Amitriptyline; Analgesics, Opioid; Anti-Inflammatory Agen

2015
Naproxen With Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo for Treating Acute Low Back Pain: A Randomized Clinical Trial.
    JAMA, 2015, Oct-20, Volume: 314, Issue:15

    Topics: Acetaminophen; Acute Disease; Adult; Aged; Amitriptyline; Analgesics, Opioid; Anti-Inflammatory Agen

2015
Naproxen With Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo for Treating Acute Low Back Pain: A Randomized Clinical Trial.
    JAMA, 2015, Oct-20, Volume: 314, Issue:15

    Topics: Acetaminophen; Acute Disease; Adult; Aged; Amitriptyline; Analgesics, Opioid; Anti-Inflammatory Agen

2015
Naproxen With Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo for Treating Acute Low Back Pain: A Randomized Clinical Trial.
    JAMA, 2015, Oct-20, Volume: 314, Issue:15

    Topics: Acetaminophen; Acute Disease; Adult; Aged; Amitriptyline; Analgesics, Opioid; Anti-Inflammatory Agen

2015
Naproxen With Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo for Treating Acute Low Back Pain: A Randomized Clinical Trial.
    JAMA, 2015, Oct-20, Volume: 314, Issue:15

    Topics: Acetaminophen; Acute Disease; Adult; Aged; Amitriptyline; Analgesics, Opioid; Anti-Inflammatory Agen

2015
Naproxen With Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo for Treating Acute Low Back Pain: A Randomized Clinical Trial.
    JAMA, 2015, Oct-20, Volume: 314, Issue:15

    Topics: Acetaminophen; Acute Disease; Adult; Aged; Amitriptyline; Analgesics, Opioid; Anti-Inflammatory Agen

2015
Naproxen With Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo for Treating Acute Low Back Pain: A Randomized Clinical Trial.
    JAMA, 2015, Oct-20, Volume: 314, Issue:15

    Topics: Acetaminophen; Acute Disease; Adult; Aged; Amitriptyline; Analgesics, Opioid; Anti-Inflammatory Agen

2015
Naproxen With Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo for Treating Acute Low Back Pain: A Randomized Clinical Trial.
    JAMA, 2015, Oct-20, Volume: 314, Issue:15

    Topics: Acetaminophen; Acute Disease; Adult; Aged; Amitriptyline; Analgesics, Opioid; Anti-Inflammatory Agen

2015
Naproxen With Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo for Treating Acute Low Back Pain: A Randomized Clinical Trial.
    JAMA, 2015, Oct-20, Volume: 314, Issue:15

    Topics: Acetaminophen; Acute Disease; Adult; Aged; Amitriptyline; Analgesics, Opioid; Anti-Inflammatory Agen

2015
Naproxen With Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo for Treating Acute Low Back Pain: A Randomized Clinical Trial.
    JAMA, 2015, Oct-20, Volume: 314, Issue:15

    Topics: Acetaminophen; Acute Disease; Adult; Aged; Amitriptyline; Analgesics, Opioid; Anti-Inflammatory Agen

2015
Naproxen With Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo for Treating Acute Low Back Pain: A Randomized Clinical Trial.
    JAMA, 2015, Oct-20, Volume: 314, Issue:15

    Topics: Acetaminophen; Acute Disease; Adult; Aged; Amitriptyline; Analgesics, Opioid; Anti-Inflammatory Agen

2015
Naproxen With Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo for Treating Acute Low Back Pain: A Randomized Clinical Trial.
    JAMA, 2015, Oct-20, Volume: 314, Issue:15

    Topics: Acetaminophen; Acute Disease; Adult; Aged; Amitriptyline; Analgesics, Opioid; Anti-Inflammatory Agen

2015
Naproxen With Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo for Treating Acute Low Back Pain: A Randomized Clinical Trial.
    JAMA, 2015, Oct-20, Volume: 314, Issue:15

    Topics: Acetaminophen; Acute Disease; Adult; Aged; Amitriptyline; Analgesics, Opioid; Anti-Inflammatory Agen

2015
Naproxen With Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo for Treating Acute Low Back Pain: A Randomized Clinical Trial.
    JAMA, 2015, Oct-20, Volume: 314, Issue:15

    Topics: Acetaminophen; Acute Disease; Adult; Aged; Amitriptyline; Analgesics, Opioid; Anti-Inflammatory Agen

2015
Naproxen With Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo for Treating Acute Low Back Pain: A Randomized Clinical Trial.
    JAMA, 2015, Oct-20, Volume: 314, Issue:15

    Topics: Acetaminophen; Acute Disease; Adult; Aged; Amitriptyline; Analgesics, Opioid; Anti-Inflammatory Agen

2015
Randomized and controlled prospective trials of Ultrasound-guided spinal nerve posterior ramus pulsed radiofrequency treatment for lower back post-herpetic neuralgia.
    La Clinica terapeutica, 2015, Volume: 166, Issue:5

    Topics: Administration, Oral; Adult; Aged; Amines; Amitriptyline; Analgesics; Celecoxib; Cyclohexanecarboxyl

2015
Comparison of naproxen with cyclobenzaprine, oxycodone-acetaminophen, and placebo for the treatment of acute low back pain.
    CJEM, 2016, Volume: 18, Issue:6

    Topics: Acetaminophen; Acute Disease; Administration, Oral; Adult; Amitriptyline; Dose-Response Relationship

2016
Is low-dose amitriptyline effective in the management of chronic low back pain? Study protocol for a randomised controlled trial.
    Trials, 2016, 10-22, Volume: 17, Issue:1

    Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Chronic Pain; Clinical Pro

2016
Cyclobenzaprine ER for muscle spasm associated with low back and neck pain: two randomized, double-blind, placebo-controlled studies of identical design.
    Current medical research and opinion, 2009, Volume: 25, Issue:5

    Topics: Adolescent; Adult; Aged; Algorithms; Amitriptyline; Delayed-Action Preparations; Double-Blind Method

2009
A randomized trial of fluoxetine versus amitriptyline in musculo-skeletal pain.
    The Israel journal of psychiatry and related sciences, 2001, Volume: 38, Issue:2

    Topics: Adolescent; Adult; Aged; Amitriptyline; Female; Fluoxetine; Humans; Low Back Pain; Male; Middle Aged

2001

Other Studies

14 other studies available for amitriptyline and Low Back Ache

ArticleYear
Does Flexeril Work? Utility of Muscle Relaxants in Lower Back Pain.
    The Journal of emergency medicine, 2022, Volume: 62, Issue:5

    Topics: Amitriptyline; Humans; Low Back Pain; Muscles; Vasodilator Agents

2022
No benefit from amitriptyline for chronic low back pain?
    Drug and therapeutics bulletin, 2020, Volume: 58, Issue:4

    Topics: Amitriptyline; Chronic Pain; Humans; Low Back Pain; Randomized Controlled Trials as Topic; Treatment

2020
Effect of low-dose amitriptyline on low back pain with a neuropathic component: a post hoc analysis.
    The spine journal : official journal of the North American Spine Society, 2021, Volume: 21, Issue:6

    Topics: Amitriptyline; Analgesics; Humans; Low Back Pain; Neuralgia; Pain Measurement

2021
Low-Dose Amitriptyline for Chronic Low Back Pain.
    JAMA internal medicine, 2019, 03-01, Volume: 179, Issue:3

    Topics: Amitriptyline; Chronic Pain; Humans; Low Back Pain; Pain Measurement

2019
Low-Dose Amitriptyline for Chronic Low Back Pain.
    JAMA internal medicine, 2019, 03-01, Volume: 179, Issue:3

    Topics: Amitriptyline; Chronic Pain; Humans; Low Back Pain; Pain Measurement

2019
Low-Dose Amitriptyline for Chronic Low Back Pain-Reply.
    JAMA internal medicine, 2019, 03-01, Volume: 179, Issue:3

    Topics: Amitriptyline; Chronic Pain; Humans; Low Back Pain; Pain Measurement

2019
ACP Journal Club. In acute low back pain, adding oxycodone/acetaminophen or cyclobenzaprine to naproxen did not improve pain or function.
    Annals of internal medicine, 2016, Feb-16, Volume: 164, Issue:4

    Topics: Acetaminophen; Amitriptyline; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Female; H

2016
PURLs: More isn't better with acute low back pain treatment.
    The Journal of family practice, 2016, Volume: 65, Issue:6

    Topics: Acetaminophen; Amitriptyline; Drug Combinations; Female; Humans; Low Back Pain; Male; Muscle Relaxan

2016
Second-Order Peer Reviews of Clinically Relevant Articles for the Physiatrist: Naproxen with Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo to Treating Acute Low Back Pain: A Randomized Clinical Trial.
    American journal of physical medicine & rehabilitation, 2017, Volume: 96, Issue:6

    Topics: Acetaminophen; Amitriptyline; Humans; Low Back Pain; Naproxen; Oxycodone; Peer Review; Physiatrists

2017
The effectiveness of tricyclic antidepressants on lumbar spinal stenosis.
    Bulletin of the NYU hospital for joint diseases, 2010, Volume: 68, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Amitriptyline; Analgesics; Antidepressive Agents, Tricyclic; Female;

2010
Chronic coccydynia in adolescents. A series of 53 patients.
    European journal of physical and rehabilitation medicine, 2011, Volume: 47, Issue:2

    Topics: Adolescent; Adult; Age Factors; Amitriptyline; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, N

2011
Dercum's disease (Adiposis dolorosa): delayed diagnosis in a patient with cervical cancer.
    Journal of palliative care, 2004,Winter, Volume: 20, Issue:4

    Topics: Adiposis Dolorosa; Adult; Amitriptyline; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Antide

2004
Persistent low back pain.
    The New England journal of medicine, 2005, Sep-01, Volume: 353, Issue:9

    Topics: Amitriptyline; Analgesics, Non-Narcotic; Chronic Disease; Humans; Low Back Pain; Muscle Relaxants, C

2005
Efficacy and safety of acupuncture for the treatment of non-specific acute low back pain: a randomised controlled multicentre trial protocol [ISRCTN65814467].
    BMC complementary and alternative medicine, 2006, Apr-21, Volume: 6

    Topics: Acetaminophen; Acupuncture; Acute Disease; Adult; Amitriptyline; Analgesics; Bayes Theorem; Clinical

2006