amitriptyline has been researched along with Liver Diseases in 4 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Liver Diseases: Pathological processes of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Thus, this adverse effect could be avoided by monitoring levels and reducing dosage when appropriate." | 1.26 | Tricyclic-antidepressant-induced delirium and plasma drug concentration. ( Preskorn, SH; Simpson, S, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pies, R | 1 |
| Preskorn, SH | 1 |
| Simpson, S | 1 |
| Hall, TJ | 1 |
| James, PR | 1 |
| Cambridge, G | 1 |
| Cunningham, ML | 1 |
4 other studies available for amitriptyline and Liver Diseases
| Article | Year |
|---|---|
Capgras phenomenon, delirium, and transient hepatic dysfunction.
Topics: Adolescent; Amitriptyline; Capgras Syndrome; Chemical and Drug Induced Liver Injury; Delirium; Drug | 1982 |
Tricyclic-antidepressant-induced delirium and plasma drug concentration.
Topics: Adult; Aged; Amitriptyline; Delirium; Depressive Disorder; Dose-Response Relationship, Drug; Female; | 1982 |
Development of an in vitro hepatotoxicity assay for assessing the effects of chronic drug exposure.
Topics: Acetaminophen; Amitriptyline; Cell Line; Cells, Cultured; Chemical and Drug Induced Liver Injury; Hu | 1993 |
Acute hepatic necrosis following treatment with amitriptyline and diazepam.
Topics: Amitriptyline; Depression; Diazepam; Female; Humans; Liver Diseases; Middle Aged | 1965 |