amitriptyline has been researched along with Kidney Diseases in 9 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| " treated ureterally obstructed mice with the tricyclic antidepressant amitriptyline and found that this inhibited inflammation, myofibroblast formation, and several other indices of renal fibrosis." | 7.75 | Pleiotropic effects of amitriptyline ameliorate renal fibrosis. ( Morrissey, JJ, 2009) |
| "Seven patients with diabetes of ten to 24 years' duration and renal insufficiency were treated with fluphenazine and amitriptyline in an attempt to control severe pain in the extremities." | 7.66 | Diabetic neuropathic pain: control by amitriptyline and fluphenazine in renal insufficiency. ( Drager, AM; Mitas, JA; Mosley, CA, 1983) |
| "Amitriptyline is a pleiotropic tricyclic antidepressant, which has anti-oxidant and anti-inflammatory properties." | 5.35 | Amitriptyline attenuates interstitial inflammation and ameliorates the progression of renal fibrosis. ( Achar, E; Collares, CF; Maciel, TT; Schor, N; Teixeira, VP, 2009) |
| " Corresponding to increase in plasma ceramide, the HFD significantly increased the body weight gain, plasma leptin concentration, urinary total protein and albumin excretion, glomerular damage index, and adipose tissue ASMase activity compared with the LFD-fed mice." | 3.76 | Role of sphingolipid mediator ceramide in obesity and renal injury in mice fed a high-fat diet. ( Boini, KM; Li, PL; Poklis, JL; Xia, M; Zhang, C, 2010) |
| " treated ureterally obstructed mice with the tricyclic antidepressant amitriptyline and found that this inhibited inflammation, myofibroblast formation, and several other indices of renal fibrosis." | 3.75 | Pleiotropic effects of amitriptyline ameliorate renal fibrosis. ( Morrissey, JJ, 2009) |
| "Seven patients with diabetes of ten to 24 years' duration and renal insufficiency were treated with fluphenazine and amitriptyline in an attempt to control severe pain in the extremities." | 3.66 | Diabetic neuropathic pain: control by amitriptyline and fluphenazine in renal insufficiency. ( Drager, AM; Mitas, JA; Mosley, CA, 1983) |
| "Buspirone was not removed by hemodialysis." | 2.37 | Metabolism and disposition of buspirone. ( Gammans, RE; LaBudde, JA; Mayol, RF, 1986) |
| "Amitriptyline is a pleiotropic tricyclic antidepressant, which has anti-oxidant and anti-inflammatory properties." | 1.35 | Amitriptyline attenuates interstitial inflammation and ameliorates the progression of renal fibrosis. ( Achar, E; Collares, CF; Maciel, TT; Schor, N; Teixeira, VP, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (55.56) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kuo, A | 1 |
| Nicholson, JR | 1 |
| Corradini, L | 1 |
| Smith, MT | 1 |
| Achar, E | 1 |
| Maciel, TT | 1 |
| Collares, CF | 1 |
| Teixeira, VP | 1 |
| Schor, N | 1 |
| Morrissey, JJ | 1 |
| Boini, KM | 1 |
| Zhang, C | 1 |
| Xia, M | 1 |
| Poklis, JL | 1 |
| Li, PL | 1 |
| Bach, O | 1 |
| Kästner, I | 1 |
| Mitas, JA | 1 |
| Mosley, CA | 1 |
| Drager, AM | 1 |
| Harvengt, C | 1 |
| Desager, JP | 1 |
| Vanderbist, M | 1 |
| Bogaert, M | 1 |
| Moerman, E | 1 |
| Gammans, RE | 1 |
| Mayol, RF | 1 |
| LaBudde, JA | 1 |
| Kilpatrick, R | 1 |
| Smith, AJ | 1 |
2 reviews available for amitriptyline and Kidney Diseases
| Article | Year |
|---|---|
Metabolism and disposition of buspirone.
Topics: Absorption; Administration, Oral; Adolescent; Adult; Aged; Aging; Amitriptyline; Animals; Anxiety Di | 1986 |
Advances in medicine.
Topics: Amitriptyline; Cholera; Coronary Disease; Crohn Disease; Diabetes Mellitus; Diet Therapy; Diverticul | 1971 |
7 other studies available for amitriptyline and Kidney Diseases
| Article | Year |
|---|---|
Establishment and characterisation of a stavudine (d4T)-induced rat model of antiretroviral toxic neuropathy (ATN) using behavioural and pharmacological methods.
Topics: Amitriptyline; Animals; Anti-Retroviral Agents; Kidney Diseases; Male; Meloxicam; Quality of Life; R | 2019 |
Amitriptyline attenuates interstitial inflammation and ameliorates the progression of renal fibrosis.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Biomarkers; Cell Movement; Disease Progres | 2009 |
Pleiotropic effects of amitriptyline ameliorate renal fibrosis.
Topics: Amitriptyline; Animals; Fibroblasts; Fibrosis; Inflammation; Kidney Diseases; Mice | 2009 |
Role of sphingolipid mediator ceramide in obesity and renal injury in mice fed a high-fat diet.
Topics: Adipose Tissue; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Blood Pressure; Body Weigh | 2010 |
[Undesired drug side effects and drug-induced damage. II. Centrally acting drugs].
Topics: Adult; Amitriptyline; Autonomic Nervous System Diseases; Basal Ganglia Diseases; Central Nervous Sys | 1984 |
Diabetic neuropathic pain: control by amitriptyline and fluphenazine in renal insufficiency.
Topics: Adult; Aged; Amitriptyline; Diabetic Neuropathies; Drug Therapy, Combination; Female; Fluphenazine; | 1983 |
Sympathetic nervous system response in acute cardiovascular toxicity induced by amitriptyline in conscious rabbits.
Topics: Amitriptyline; Animals; Blood Pressure; Body Temperature; Cardiovascular Diseases; Catecholamines; E | 1978 |