Page last updated: 2024-10-22

amitriptyline and Ischemia

amitriptyline has been researched along with Ischemia in 4 studies

Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.

Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.

Research Excerpts

ExcerptRelevanceReference
" Both had received a commonly used psychotropic drug in large dosage before the acute episode."1.27Ischaemic colitis associated with psychotropic drugs. ( Gollock, JM; Thomson, JP, 1984)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Mohamud Yusuf, A1
Hagemann, N1
Zhang, X1
Zafar, M1
Hussner, T1
Bromkamp, C1
Martiny, C1
Tertel, T1
Börger, V1
Schumacher, F1
Solari, FA1
Hasenberg, M1
Kleinschnitz, C1
Doeppner, TR1
Kleuser, B1
Sickmann, A1
Gunzer, M1
Giebel, B1
Kolesnick, R1
Gulbins, E1
Hermann, DM1
Loram, LC1
Mitchell, D1
Skosana, M1
Fick, LG1
Millecamps, M1
Coderre, TJ1
Gollock, JM1
Thomson, JP1

Other Studies

4 other studies available for amitriptyline and Ischemia

ArticleYear
Acid sphingomyelinase deactivation post-ischemia promotes brain angiogenesis and remodeling by small extracellular vesicles.
    Basic research in cardiology, 2022, Volume: 117, Issue:1

    Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Ceramides; Desipramine; Endothelial Cells; Ext

2022
Tramadol is more effective than morphine and amitriptyline against ischaemic pain but not thermal pain in rats.
    Pharmacological research, 2007, Volume: 56, Issue:1

    Topics: Amitriptyline; Analgesics; Animals; Female; Hot Temperature; Hyperalgesia; Ischemia; Male; Morphine;

2007
Rats with chronic post-ischemia pain exhibit an analgesic sensitivity profile similar to human patients with complex regional pain syndrome--type I.
    European journal of pharmacology, 2008, Mar-31, Volume: 583, Issue:1

    Topics: Amitriptyline; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dos

2008
Ischaemic colitis associated with psychotropic drugs.
    Postgraduate medical journal, 1984, Volume: 60, Issue:706

    Topics: Amitriptyline; Chlorpromazine; Colitis; Colon; Female; Humans; Ischemia; Middle Aged

1984