amitriptyline has been researched along with Intraocular Pressure in 7 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Intraocular Pressure: The pressure of the fluids in the eye.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Both amitriptyline and nortriptyline applied conjunctivally produced pupil size enlargement, intraocular pressure decrease and a fall in aqueous humor formation." | 3.65 | [Effect of amitriptyline and nortriptyline on the intracular pressure and aqueous humor dynamics in rabbits (author's transl)]. ( Belmonte, A; Tato, F, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (85.71) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Molyneux, PD | 1 |
| Jordan, K | 1 |
| Kopera, H | 2 |
| Fluch, N | 1 |
| Harpf, H | 1 |
| Klein, WW | 1 |
| Stulemeijer, SM | 1 |
| Bieganowski, L | 1 |
| Czerwiński, M | 1 |
| Gol'dovskaia, IL | 1 |
| Tato, F | 1 |
| Belmonte, A | 1 |
| Bojanovsky, J | 1 |
| Tölle, R | 1 |
1 review available for amitriptyline and Intraocular Pressure
| Article | Year |
|---|---|
[Psychotropic therapy and intraocular pressure].
Topics: Amitriptyline; Analgesics; Antidepressive Agents; Chlorpromazine; Diazepam; Diphenhydramine; Eye Dis | 1975 |
3 trials available for amitriptyline and Intraocular Pressure
| Article | Year |
|---|---|
Cardiovascular effects of mianserin--a comparative study with amitriptyline and a placebo in healthy subjects.
Topics: Adolescent; Adult; Amitriptyline; Blood Pressure; Dibenzazepines; Double-Blind Method; Electrocardio | 1980 |
Anticholinergic and blood pressure effects of mianserin, amitriptyline and placebo.
Topics: Accommodation, Ocular; Adult; Amitriptyline; Blood Pressure; Clinical Trials as Topic; Dibenzazepine | 1978 |
[Dihydroergotamine for treatment of vascular side-effects of thymoleptics (author's transl)].
Topics: Amitriptyline; Brachial Artery; Clinical Trials as Topic; Depression; Drug Interactions; Ergotamine; | 1974 |
3 other studies available for amitriptyline and Intraocular Pressure
| Article | Year |
|---|---|
Migraine, an open and shut case?
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Diagnosis, Differential; Female; Glaucoma, Angle-Cl | 2010 |
[Decompensation of glaucoma after administration of tricyclic antidepressants and anxiolytic drugs].
Topics: Amitriptyline; Depression; Female; Glaucoma; Humans; Imipramine; Intraocular Pressure; Middle Aged; | 1980 |
[Effect of amitriptyline and nortriptyline on the intracular pressure and aqueous humor dynamics in rabbits (author's transl)].
Topics: Amitriptyline; Animals; Aqueous Humor; Drug Synergism; Female; Intraocular Pressure; Male; Norepinep | 1975 |