amitriptyline has been researched along with Intellectual Disability in 13 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Intellectual Disability: Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual has an intellectual disability. IQ scores between 70 and 79 are in the borderline range. Scores below 67 are in the disabled range. (from Joynt, Clinical Neurology, 1992, Ch55, p28)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (92.31) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| MANS, J | 1 |
| SENES, M | 1 |
| Small, JG | 1 |
| Small, IF | 1 |
| Drew, LR | 1 |
| Kinze, W | 1 |
| Strian, F | 1 |
| Albert, W | 1 |
| Klicpera, C | 1 |
| Langee, HR | 1 |
| Conlon, M | 1 |
| Grof, P | 1 |
| Saxena, B | 1 |
| Cantor, R | 1 |
| Daigle, L | 1 |
| Hetherington, D | 1 |
| Haines, T | 1 |
| Kashiwagi, T | 1 |
| McClure, JN | 1 |
| Wetzel, RD | 1 |
| Geisler, A | 1 |
| Thomsen, K | 1 |
| St-Jean, A | 1 |
| Ban, TA | 1 |
| Scott, J | 1 |
| D'Hollander, L | 1 |
| Vaneck, L | 1 |
| Reid, AH | 1 |
| Nievoll, A | 1 |
4 trials available for amitriptyline and Intellectual Disability
| Article | Year |
|---|---|
Doxepin versus amitriptyline in depression: a sequential double-blind study.
Topics: Amitriptyline; Anxiety; Depression; Doxepin; Female; Humans; Hypochondriasis; Intellectual Disabilit | 1974 |
Drug defaulting estimated by the use of a drug marker.
Topics: Adult; Amitriptyline; Attitude to Health; Chlorprothixene; Chromatography, Thin Layer; Ethanol; Fema | 1973 |
The effect of a protriptyline-perphenazine combination in chronic psychiatric patients.
Topics: Adolescent; Adult; Amitriptyline; Clinical Trials as Topic; Depression; Female; Humans; Intellectual | 1966 |
[Treatment of enuresis by imipramine and amitriptyline in retarded children].
Topics: Adolescent; Amitriptyline; Child; Child, Preschool; Clinical Trials as Topic; Enuresis; Humans; Imip | 1967 |
9 other studies available for amitriptyline and Intellectual Disability
| Article | Year |
|---|---|
[AMITRIPTYLINE OR LAROXYL IN DEPRESSIVE SYNDROMES].
Topics: Amitriptyline; Bipolar Disorder; Depression; Depressive Disorder; Depressive Disorder, Major; Epilep | 1964 |
EEG spikes in non-epileptic psychiatric patients.
Topics: Adolescent; Adult; Aged; Amitriptyline; Antisocial Personality Disorder; Barbiturates; Brain; Brain | 1967 |
Drug control of incontinence in adult mental defectives.
Topics: Amitriptyline; Defecation; Encopresis; Enuresis; Humans; Imipramine; Intellectual Disability; Male | 1967 |
[Therapy with psychotropic agents of mentally retarded children].
Topics: Amitriptyline; Child; Chlorpromazine; Haloperidol; Humans; Intellectual Disability; Psychotropic Dru | 1983 |
Course of depressive mood and psychomotor activation in endogenous depression.
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Depression; Electroconvuls | 1979 |
Predictors of response to antidepressant medications.
Topics: Aggression; Amitriptyline; Antidepressive Agents; Depression; Doxepin; Follow-Up Studies; Humans; In | 1992 |
Headache and psychiatric disorders.
Topics: Adolescent; Adult; Affective Symptoms; Age Factors; Aged; Alcoholism; Amitriptyline; Antisocial Pers | 1972 |
Psychoses in adult mental defectives. I. Manic depressive psychosis.
Topics: Adult; Affective Symptoms; Aged; Amitriptyline; Bipolar Disorder; Catatonia; Delusions; Diagnosis, D | 1972 |
[Therapeutic experiences with oxazepam--a derivative of the benzodiazepine series--in child and adolescent psychiatry].
Topics: Adolescent; Adolescent Psychiatry; Adult; Aggression; Amitriptyline; Anticonvulsants; Brain Damage, | 1971 |