amitriptyline has been researched along with Injury, Myocardial Reperfusion in 3 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The present study was undertaken to compare the effects of amitriptyline and mianserin with those of tianeptine, an atypical tricyclic antidepressant drug, in rat isolated working heart subjected to a local myocardial ischemia." | 3.68 | Absence of relationship between antiarrhythmic effects of antidepressant drugs and lipid peroxidation. ( Abadie, C; Ben Baouali, A; Bril, A; Maupoil, V; Rochette, L, 1993) |
| "Amitriptyline (AMY) is a tricyclic anti-depressant that has recently been shown to have anti-inflammatory properties." | 1.42 | Amitriptyline pharmacologically preconditions rat hearts against cardiac ischemic-reperfusion injury. ( Hutchinson, M; Lee, SM; Saint, DA; Staikopoulos, V, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, SM | 1 |
| Hutchinson, M | 1 |
| Staikopoulos, V | 1 |
| Saint, DA | 1 |
| Zeng, C | 1 |
| Zhu, Z | 1 |
| Liu, Q | 1 |
| Bril, A | 1 |
| Abadie, C | 1 |
| Ben Baouali, A | 1 |
| Maupoil, V | 1 |
| Rochette, L | 1 |
3 other studies available for amitriptyline and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Amitriptyline pharmacologically preconditions rat hearts against cardiac ischemic-reperfusion injury.
Topics: Amitriptyline; Animals; Cardiotonic Agents; Heart; Ischemic Preconditioning, Myocardial; Male; Myoca | 2015 |
HMGB1 is responsible for Amitriptyline-mediated cardiac protection from ischemic-reperfusion injury.
Topics: Amitriptyline; Animals; Biomarkers; Disease Models, Animal; HMGB1 Protein; Myocardial Reperfusion In | 2016 |
Absence of relationship between antiarrhythmic effects of antidepressant drugs and lipid peroxidation.
Topics: Amitriptyline; Animals; Anti-Arrhythmia Agents; Antidepressive Agents, Tricyclic; Brain; Cardiac Out | 1993 |