amitriptyline has been researched along with Infant, Newborn, Diseases in 2 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Infant, Newborn, Diseases: Diseases of newborn infants present at birth (congenital) or developing within the first month of birth. It does not include hereditary diseases not manifesting at birth or within the first 30 days of life nor does it include inborn errors of metabolism. Both HEREDITARY DISEASES and METABOLISM, INBORN ERRORS are available as general concepts.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The absence of neonatal seizures is a robust and important clinical differentiator between KCNQ2 gain-of-function and loss-of-function variants." | 1.72 | KCNQ2 R144 variants cause neurodevelopmental disability with language impairment and autistic features without neonatal seizures through a gain-of-function mechanism. ( Ambrosino, P; Amin, H; Bayat, A; Brilstra, E; Carotenuto, L; Cooper, EC; de Bellescize, J; Devinsky, O; Edery, P; Emrick, L; Goizet, C; Hong, W; Kleefstra, T; Kluger, G; Korenke, GC; Lee, HK; Lesca, G; Mefford, HC; Miceli, F; Michaud, V; Milh, M; Millevert, C; Mosca, I; Møller, RS; Risen, S; Riviello, J; Sands, T; Schrader, D; Soldovieri, MV; Taglialatela, M; Van-Gils, J; Ville, D; Weckhuysen, S; Willemsen, MH, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Miceli, F | 1 |
| Millevert, C | 1 |
| Soldovieri, MV | 1 |
| Mosca, I | 1 |
| Ambrosino, P | 1 |
| Carotenuto, L | 1 |
| Schrader, D | 1 |
| Lee, HK | 1 |
| Riviello, J | 1 |
| Hong, W | 1 |
| Risen, S | 1 |
| Emrick, L | 1 |
| Amin, H | 1 |
| Ville, D | 1 |
| Edery, P | 1 |
| de Bellescize, J | 1 |
| Michaud, V | 1 |
| Van-Gils, J | 1 |
| Goizet, C | 1 |
| Willemsen, MH | 1 |
| Kleefstra, T | 1 |
| Møller, RS | 1 |
| Bayat, A | 1 |
| Devinsky, O | 1 |
| Sands, T | 1 |
| Korenke, GC | 1 |
| Kluger, G | 1 |
| Mefford, HC | 1 |
| Brilstra, E | 1 |
| Lesca, G | 1 |
| Milh, M | 1 |
| Cooper, EC | 1 |
| Taglialatela, M | 1 |
| Weckhuysen, S | 1 |
| Idänpään-Heikkilä, J | 1 |
| Saxén, L | 1 |
2 other studies available for amitriptyline and Infant, Newborn, Diseases
| Article | Year |
|---|---|
KCNQ2 R144 variants cause neurodevelopmental disability with language impairment and autistic features without neonatal seizures through a gain-of-function mechanism.
Topics: Amitriptyline; Autistic Disorder; Epilepsy; Gain of Function Mutation; Humans; Infant, Newborn; Infa | 2022 |
Possible teratogenicity of imipramine-chloropyramine.
Topics: Abnormalities, Drug-Induced; Adult; Amitriptyline; Antidepressive Agents; Benzyl Compounds; Drug Com | 1973 |