amitriptyline has been researched along with Hypersensitivity in 4 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Hypersensitivity: Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this open study, amitriptyline appears to decrease stress-induced electrical hypersensitivity; this effect is independent of autonomic tone." | 9.14 | Amitriptyline modifies the visceral hypersensitivity response to acute stress in the irritable bowel syndrome. ( Emmanuel, AV; Kamm, MA; Murray, CD; Pitcher, MC; Roy, AJ; Thoua, NM; Winchester, WJ, 2009) |
| "In this open study, amitriptyline appears to decrease stress-induced electrical hypersensitivity; this effect is independent of autonomic tone." | 5.14 | Amitriptyline modifies the visceral hypersensitivity response to acute stress in the irritable bowel syndrome. ( Emmanuel, AV; Kamm, MA; Murray, CD; Pitcher, MC; Roy, AJ; Thoua, NM; Winchester, WJ, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Casanova, MJ | 1 |
| Santander, C | 1 |
| Gisbert, JP | 1 |
| Thoua, NM | 1 |
| Murray, CD | 1 |
| Winchester, WJ | 1 |
| Roy, AJ | 1 |
| Pitcher, MC | 1 |
| Kamm, MA | 1 |
| Emmanuel, AV | 1 |
| BATTERMAN, RC | 1 |
| KAUFMAN, JE | 1 |
| MOURATOFF, GJ | 1 |
| Sanger, MD | 1 |
2 trials available for amitriptyline and Hypersensitivity
| Article | Year |
|---|---|
Amitriptyline modifies the visceral hypersensitivity response to acute stress in the irritable bowel syndrome.
Topics: Adult; Amitriptyline; Analgesics, Non-Narcotic; Female; Humans; Hypersensitivity; Irritable Bowel Sy | 2009 |
The treatment of anxiety and depression in the allergic patient.
Topics: Adolescent; Adult; Aged; Amitriptyline; Angioedema; Anxiety; Asthma; Clinical Trials as Topic; Depre | 1969 |
2 other studies available for amitriptyline and Hypersensitivity
| Article | Year |
|---|---|
Rectal hypersensitivity in patients with quiescent ulcerative colitis.
Topics: Adrenergic Uptake Inhibitors; Adult; Amitriptyline; Colitis, Ulcerative; Fecal Incontinence; Humans; | 2015 |
CLINICAL USE OF AMITRIPTYLINE FOR THE TREATMENT OF PSYCHONEUROTIC REACTIVE ANXIETY AND DEPRESSION.
Topics: Amitriptyline; Anxiety; Arthritis, Rheumatoid; Asthma; Coronary Disease; Depression; Diabetes Mellit | 1964 |