amitriptyline has been researched along with Hypercapnia in 1 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Hypercapnia: A clinical manifestation of abnormal increase in the amount of carbon dioxide in arterial blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Postmorphine Paco2 was significantly higher in the amitriptyline and combination groups at all time points over the 240 min, and in the gabapentin group at 10 and 30 min after morphine injection (P<0." | 1.35 | The effect of amitriptyline, gabapentin, and carbamazepine on morphine-induced hypercarbia in rabbits. ( Garcia-Bournissen, F; Hoshino, N; Ito, S; Kapur, B; Koren, G; Kozer, E; Leombruno, J; Levichek, Z; Taguchi, N, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kozer, E | 1 |
| Levichek, Z | 1 |
| Hoshino, N | 1 |
| Kapur, B | 1 |
| Leombruno, J | 1 |
| Taguchi, N | 1 |
| Garcia-Bournissen, F | 1 |
| Koren, G | 1 |
| Ito, S | 1 |
1 other study available for amitriptyline and Hypercapnia
| Article | Year |
|---|---|
The effect of amitriptyline, gabapentin, and carbamazepine on morphine-induced hypercarbia in rabbits.
Topics: Amines; Amitriptyline; Analgesics, Opioid; Animals; Anticonvulsants; Antidepressive Agents, Tricycli | 2008 |