amitriptyline has been researched along with Heart Failure in 8 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To conduct population-based analyses comparing the risk of serious cardiovascular (CV) events (eg, acute myocardial infarction, stroke, congestive heart failure) associated with treatment with milnacipran compared with venlafaxine and amitriptyline, 2 other commonly prescribed drugs that also inhibit reuptake of norepinephrine and serotonin." | 3.77 | Epidemiologic Evaluation of Cardiovascular Risk in Patients Receiving Milnacipran, Venlafaxine, or Amitriptyline: Evidence from French Health Data. ( Boerstoel-Streefland, M; Duh, MS; Guérin, A; Jiang, W; Lefebvre, P; Mease, PJ; Vekeman, F; Zimetbaum, PJ, 2011) |
| " The case presentation illustrates the role of pregabalin in successful medical management of this chronic pain disorder, as well as the management of common psychiatric morbidities associated with this condition." | 3.74 | Pregabalin-induced remission in a 62-year-old woman with a 20-year history of vulvodynia. ( Jerome, L, 2007) |
| " In 1 patient, acute myocardial infarction developed after two 10-mg doses of nortriptyline." | 3.66 | Cardiovascular side effects of long-term therapy with tricyclic antidepressants in the aged. ( Oei, LS; Rodstein, M, 1979) |
| "She had had chronic paranoid schizophrenia for 35 years and had been taking medications to control her psychiatric disorder for the past 10 years." | 1.32 | Drug-induced toxic myocarditis. ( Ansari, A; Berntson, DG; Maron, BJ, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (62.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mease, PJ | 1 |
| Zimetbaum, PJ | 1 |
| Duh, MS | 1 |
| Vekeman, F | 1 |
| Guérin, A | 1 |
| Boerstoel-Streefland, M | 1 |
| Jiang, W | 1 |
| Lefebvre, P | 1 |
| Ansari, A | 1 |
| Maron, BJ | 1 |
| Berntson, DG | 1 |
| Jerome, L | 1 |
| Morse, RH | 1 |
| Luccioni, R | 1 |
| Frances, Y | 1 |
| Piéri, B | 1 |
| Bouteau, JM | 1 |
| Faugère, G | 1 |
| Gatau-Pelanchon, J | 1 |
| Gérard, R | 1 |
| Rodstein, M | 1 |
| Oei, LS | 1 |
| Bain, DJ | 1 |
| Turner, T | 1 |
| Greeff, K | 1 |
| Wagner, J | 1 |
8 other studies available for amitriptyline and Heart Failure
| Article | Year |
|---|---|
Epidemiologic Evaluation of Cardiovascular Risk in Patients Receiving Milnacipran, Venlafaxine, or Amitriptyline: Evidence from French Health Data.
Topics: Adrenergic Uptake Inhibitors; Adult; Amitriptyline; Antidepressive Agents; Cardiovascular Diseases; | 2011 |
Drug-induced toxic myocarditis.
Topics: Adrenergic Uptake Inhibitors; Aged; Amitriptyline; Antipsychotic Agents; Female; Heart Failure; Huma | 2003 |
Pregabalin-induced remission in a 62-year-old woman with a 20-year history of vulvodynia.
Topics: Amitriptyline; Analgesics; Anti-Ulcer Agents; Anticoagulants; Antidepressive Agents; Anxiety; Cardio | 2007 |
Chronic pain and the risks of psychotropics.
Topics: Amitriptyline; Chronic Disease; Female; Fluphenazine; Heart Failure; Humans; Meperidine; Middle Aged | 1984 |
[Cardiac insufficiency linked to non-IMAO antidepressive agents. Case report].
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Female; Heart Failure; Humans | 1982 |
Cardiovascular side effects of long-term therapy with tricyclic antidepressants in the aged.
Topics: Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Cardiovascular System; | 1979 |
Imipramine poisoning.
Topics: Amitriptyline; Child; Enzymes; Female; Heart Failure; Humans; Imipramine; Poisoning | 1971 |
[Animal experiments to study the cardiotoxic effect of thymoleptics].
Topics: Amitriptyline; Animals; Blood Pressure; Cats; Desipramine; Drug Synergism; Epinephrine; Heart; Heart | 1971 |