Compounds > amitriptyline
Page last updated: 2024-10-22

amitriptyline and Head and Neck Neoplasms

amitriptyline has been researched along with Head and Neck Neoplasms in 2 studies

Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.

Head and Neck Neoplasms: Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)

Research Excerpts

ExcerptRelevanceReference
"Patients treated for head and neck cancer are chronic opioid users to manage their post-treatment pain, which may entail an increased risk of addiction and overdose."3.11Study protocol of the TEC-ORL clinical trial: a randomized comparative phase II trial investigating the analgesic activity of capsaicin vs Laroxyl in head and neck Cancer survivors presenting with neuropathic pain sequelae. ( Boden, A; Bourgouin, M; Caunes-Hilary, N; Fabre, A; Filleron, T; Lodin, S; Lusque, A; Mauries, V; Moreau, C; Mounier, M; Poublanc, M, 2022)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's2 (100.00)2.80

Authors

AuthorsStudies
Boden, A2
Lusque, A2
Lodin, S2
Bourgouin, M2
Mauries, V2
Moreau, C2
Fabre, A2
Mounier, M2
Poublanc, M2
Caunes-Hilary, N2
Filleron, T2
Steel, SJ1
Robertson, CE1

Reviews

1 review available for amitriptyline and Head and Neck Neoplasms

ArticleYear
First Bite Syndrome: What Neurologists Need to Know.
    Current pain and headache reports, 2021, Mar-24, Volume: 25, Issue:5

    Topics: Acetylcholine Release Inhibitors; Amitriptyline; Analgesics, Non-Narcotic; Botulinum Toxins; Carotid

2021

Trials

1 trial available for amitriptyline and Head and Neck Neoplasms

ArticleYear
Study protocol of the TEC-ORL clinical trial: a randomized comparative phase II trial investigating the analgesic activity of capsaicin vs Laroxyl in head and neck Cancer survivors presenting with neuropathic pain sequelae.
    BMC cancer, 2022, Dec-05, Volume: 22, Issue:1

    Topics: Amitriptyline; Analgesics; Capsaicin; Clinical Trials, Phase II as Topic; Head and Neck Neoplasms; H

2022
Study protocol of the TEC-ORL clinical trial: a randomized comparative phase II trial investigating the analgesic activity of capsaicin vs Laroxyl in head and neck Cancer survivors presenting with neuropathic pain sequelae.
    BMC cancer, 2022, Dec-05, Volume: 22, Issue:1

    Topics: Amitriptyline; Analgesics; Capsaicin; Clinical Trials, Phase II as Topic; Head and Neck Neoplasms; H

2022
Study protocol of the TEC-ORL clinical trial: a randomized comparative phase II trial investigating the analgesic activity of capsaicin vs Laroxyl in head and neck Cancer survivors presenting with neuropathic pain sequelae.
    BMC cancer, 2022, Dec-05, Volume: 22, Issue:1

    Topics: Amitriptyline; Analgesics; Capsaicin; Clinical Trials, Phase II as Topic; Head and Neck Neoplasms; H

2022
Study protocol of the TEC-ORL clinical trial: a randomized comparative phase II trial investigating the analgesic activity of capsaicin vs Laroxyl in head and neck Cancer survivors presenting with neuropathic pain sequelae.
    BMC cancer, 2022, Dec-05, Volume: 22, Issue:1

    Topics: Amitriptyline; Analgesics; Capsaicin; Clinical Trials, Phase II as Topic; Head and Neck Neoplasms; H

2022