amitriptyline has been researched along with Glial Cell Tumors in 4 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the present study, we investigated the effects of chronic in vitro administration of amitriptyline, a tricyclic antidepressant, on cyclic GMP formation stimulated by 5-hydroxytryptamine (5-HT) in the neuroblastoma x glioma hybrid cell line, NG 108-15, 5-HT (0." | 3.69 | Chronic amitriptyline exposure reduces 5-HT3 receptor-mediated cyclic GMP formation in NG 108-15 cells. ( Nishida, A; Shimizu, M; Yamawaki, S; Zensho, H, 1996) |
| "Gel electrophoresis of DNA was used for estimation of DNA changes caused in C6 glioma cells by treatment with psychotropic drugs (imipramine, amitryptiline and fluoxetine)." | 3.69 | Estimation of apoptosis in C6 glioma cells treated with antidepressants. ( Kovárů, H; Lisá, V; Lukásová, E; Rittich, B; Spanová, A, 1997) |
| "Amitriptyline treatment also increased the expression of luciferase reporter gene regulated by CRE elements." | 1.35 | Antidepressants induce acute CREB phosphorylation and CRE-mediated gene expression in glial cells: a possible contribution to GDNF production. ( Hisaoka, K; Maeda, N; Takebayashi, M; Tsuchioka, M, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hisaoka, K | 1 |
| Maeda, N | 1 |
| Tsuchioka, M | 1 |
| Takebayashi, M | 1 |
| Shimizu, M | 1 |
| Nishida, A | 1 |
| Zensho, H | 1 |
| Yamawaki, S | 1 |
| Spanová, A | 1 |
| Kovárů, H | 1 |
| Lisá, V | 1 |
| Lukásová, E | 1 |
| Rittich, B | 1 |
| Rabey, JM | 1 |
| Avrahami, E | 1 |
4 other studies available for amitriptyline and Glial Cell Tumors
| Article | Year |
|---|---|
Antidepressants induce acute CREB phosphorylation and CRE-mediated gene expression in glial cells: a possible contribution to GDNF production.
Topics: Amitriptyline; Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Cell Line, Tumor; Co | 2008 |
Chronic amitriptyline exposure reduces 5-HT3 receptor-mediated cyclic GMP formation in NG 108-15 cells.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Benzamides; Bradykinin; Brain Neoplasms; Bridged Bi | 1996 |
Estimation of apoptosis in C6 glioma cells treated with antidepressants.
Topics: Amitriptyline; Antidepressive Agents; Apoptosis; DNA Fragmentation; Fluoxetine; Glioma; Humans; Imip | 1997 |
Unmasking of cerebellar tumours by amitriptyline in depressive patients.
Topics: Aged; Amitriptyline; Astrocytoma; Cerebellar Neoplasms; Depressive Disorder; Diagnosis, Differential | 1985 |