amitriptyline has been researched along with Generalized Vulvodynia in 10 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study aimed to evaluate the effectiveness of topical amitriptyline 2% in sorbolene (cetomacrogol aqueous) cream in the management of patients with entry dyspareunia caused by provoked vestibulodynia." | 7.78 | Use of amitriptyline cream in the management of entry dyspareunia due to provoked vestibulodynia. ( Pagano, R; Wong, S, 2012) |
| "Kinesiotherapy and electrotherapy additions to amitriptyline administration as well as amitriptyline alone, were effective at improving vestibular pain in women with vulvodynia." | 5.69 | Does the addition of electrical stimulation or kinesiotherapy improve outcomes of amitriptyline treatment for women with vulvodynia? A randomized clinical trial. ( Bardin, MG; De Mira, TAA; Giraldo, PC; Lenzi, J; Morin, M; Witkin, SS, 2023) |
| "Vulvodynia and pudendal neuralgia comprise significant contributors to vulvar-related pain and its impact on daily life." | 5.62 | Topical treatment of vulvodynia, dyspareunia and pudendal neuralgia: A single clinic audit of amitriptyline and oestriol in organogel. ( Chan, K; Howard, EA; Ruoss, CM; Stevenson, PG; Vancaillie, T, 2021) |
| "This study aimed to evaluate the effectiveness of topical amitriptyline 2% in sorbolene (cetomacrogol aqueous) cream in the management of patients with entry dyspareunia caused by provoked vestibulodynia." | 3.78 | Use of amitriptyline cream in the management of entry dyspareunia due to provoked vestibulodynia. ( Pagano, R; Wong, S, 2012) |
| "The etiology of vulvodynia remains unknown, making it difficult to identify or develop effective treatment methods." | 3.01 | Evaluation and Treatment of Vulvodynia: State of the Science. ( Glayzer, EJ; Glayzer, JE; He, Y; Kobak, WH; Li, H; McFarlin, BL; Schlaeger, JM; Takakura, N; Takayama, M; Villegas-Downs, M; Yajima, H, 2023) |
| "The addition of ALA/n-3 PUFAs to amitriptyline treatment in patients with VBD/PBS appears to improve outcomes and may allow for a lower dosage of amitriptyline, which may lead to fewer adverse effects." | 2.84 | Alpha Lipoic Acid Plus Omega-3 Fatty Acids for Vestibulodynia Associated With Painful Bladder Syndrome. ( Felice, R; Gambini, D; Graziottin, A; Murina, F, 2017) |
| "Vulvodynia is chronic vulvar pain or a burning sensation lasting for at least 3 months without a cause." | 1.72 | A multidisciplinary approach to a patient with vulvodynia: a successful treatment and outcome. ( Crnković, M; Djaković, I; Lugović-Mihić, L; Magdić-Turković, T; Novak-Hlebar, I; Petričević, T, 2022) |
| "Vulvodynia and pudendal neuralgia comprise significant contributors to vulvar-related pain and its impact on daily life." | 1.62 | Topical treatment of vulvodynia, dyspareunia and pudendal neuralgia: A single clinic audit of amitriptyline and oestriol in organogel. ( Chan, K; Howard, EA; Ruoss, CM; Stevenson, PG; Vancaillie, T, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 5 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Novak-Hlebar, I | 1 |
| Crnković, M | 1 |
| Djaković, I | 1 |
| Magdić-Turković, T | 1 |
| Petričević, T | 1 |
| Lugović-Mihić, L | 1 |
| Schlaeger, JM | 1 |
| Glayzer, JE | 1 |
| Villegas-Downs, M | 1 |
| Li, H | 1 |
| Glayzer, EJ | 1 |
| He, Y | 1 |
| Takayama, M | 1 |
| Yajima, H | 1 |
| Takakura, N | 1 |
| Kobak, WH | 1 |
| McFarlin, BL | 1 |
| Bardin, MG | 1 |
| Giraldo, PC | 1 |
| Lenzi, J | 1 |
| Witkin, SS | 1 |
| De Mira, TAA | 1 |
| Morin, M | 1 |
| Majeed, S | 1 |
| Abdelrahman, A | 1 |
| Ruoss, CM | 1 |
| Howard, EA | 1 |
| Chan, K | 1 |
| Stevenson, PG | 1 |
| Vancaillie, T | 1 |
| Murina, F | 2 |
| Graziottin, A | 1 |
| Felice, R | 1 |
| Gambini, D | 1 |
| van Beekhuizen, HJ | 1 |
| Oost, J | 1 |
| van der Meijden, WI | 1 |
| Bautrant, E | 1 |
| Porta, O | 1 |
| Mühlrad, H | 1 |
| Levêque, C | 1 |
| Riant, T | 1 |
| Ploteau, S | 1 |
| Valancogne, G | 1 |
| Levesque, A | 1 |
| Scurry, J | 1 |
| Manning, J | 1 |
| Fischer, G | 1 |
| Pagano, R | 1 |
| Wong, S | 1 |
2 reviews available for amitriptyline and Generalized Vulvodynia
| Article | Year |
|---|---|
Evaluation and Treatment of Vulvodynia: State of the Science.
Topics: Amitriptyline; Female; Humans; Lidocaine; Transcutaneous Electric Nerve Stimulation; Treatment Outco | 2023 |
Provoked vulvar vestibulodynia: Epidemiology in Europe, physio-pathology, consensus for first-line treatment and evaluation of second-line treatments.
Topics: Amitriptyline; Analgesics, Non-Narcotic; Botulinum Toxins; Cognitive Behavioral Therapy; Consensus; | 2019 |
2 trials available for amitriptyline and Generalized Vulvodynia
| Article | Year |
|---|---|
Does the addition of electrical stimulation or kinesiotherapy improve outcomes of amitriptyline treatment for women with vulvodynia? A randomized clinical trial.
Topics: Amitriptyline; Electric Stimulation; Female; Humans; Pain; Pain Measurement; Vulvodynia | 2023 |
Alpha Lipoic Acid Plus Omega-3 Fatty Acids for Vestibulodynia Associated With Painful Bladder Syndrome.
Topics: Adolescent; Adult; Amitriptyline; Analgesics, Non-Narcotic; Antioxidants; Cystitis, Interstitial; Do | 2017 |
6 other studies available for amitriptyline and Generalized Vulvodynia
| Article | Year |
|---|---|
A multidisciplinary approach to a patient with vulvodynia: a successful treatment and outcome.
Topics: Amitriptyline; Female; Humans; Middle Aged; Pain; Quality of Life; Treatment Outcome; Vulvodynia | 2022 |
Commentary on: "Does the addition of electrical stimulation or kinesiotherapy improve outcomes of amitriptyline treatment for women with vulvodynia? A randomized control trial".
Topics: Amitriptyline; Electric Stimulation; Female; Humans; Pain Measurement; Treatment Outcome; Vulvodynia | 2023 |
Topical treatment of vulvodynia, dyspareunia and pudendal neuralgia: A single clinic audit of amitriptyline and oestriol in organogel.
Topics: Aged; Amitriptyline; Australia; Clinical Audit; Dyspareunia; Estriol; Female; Humans; Middle Aged; P | 2021 |
Generalized unprovoked vulvodynia; A retrospective study on the efficacy of treatment with amitriptyline, gabapentin or pregabalin.
Topics: Adult; Aged; Aged, 80 and over; Amines; Amitriptyline; Analgesics; Cyclohexanecarboxylic Acids; Fema | 2018 |
Toker Cells in an Erythematous Vulva From the Case Consultation Committee of the International Society for the Study of Vulvovaginal Disease.
Topics: Amitriptyline; Analgesics, Non-Narcotic; Biopsy; Erythema; Female; Histocytochemistry; Humans; Immun | 2016 |
Use of amitriptyline cream in the management of entry dyspareunia due to provoked vestibulodynia.
Topics: Adolescent; Adult; Aged; Amitriptyline; Analgesics, Non-Narcotic; Dyspareunia; Female; Humans; Middl | 2012 |