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amitriptyline and Gastric Ulcer

amitriptyline has been researched along with Gastric Ulcer in 17 studies

Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.

Research Excerpts

ExcerptRelevanceReference
"The effects of acute systemic administration of duloxetine, amitriptyline, mirtazapine and fluoxetine were compared in experimental models of gastric ulcer in rats."7.78Evaluation of the anti-ulcerogenic activity of the antidepressants duloxetine, amitriptyline, fluoxetine and mirtazapine in different models of experimental gastric ulcer in rats. ( Fan, DS; Guo, L; Ji, CX; Li, W; Liang, ZL; Xu, RM; Zhang, JJ, 2012)
"The effects of acute systemic administration of duloxetine, amitriptyline, mirtazapine and fluoxetine were compared in experimental models of gastric ulcer in rats."3.78Evaluation of the anti-ulcerogenic activity of the antidepressants duloxetine, amitriptyline, fluoxetine and mirtazapine in different models of experimental gastric ulcer in rats. ( Fan, DS; Guo, L; Ji, CX; Li, W; Liang, ZL; Xu, RM; Zhang, JJ, 2012)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199012 (70.59)18.7374
1990's2 (11.76)18.2507
2000's1 (5.88)29.6817
2010's2 (11.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vrignaud, L1
Simon, C1
Agier, MS1
Bejan-Angoulvant, T1
Bouquet, E1
Beau-Salinas, F1
Jonville-Béra, AP1
Ji, CX1
Fan, DS1
Li, W1
Guo, L1
Liang, ZL1
Xu, RM1
Zhang, JJ1
Sen, T1
Abdulsalam, CA1
Pal, S1
Sen, S1
Karmakar, S1
Saravanan, KS1
Chaudhuri, AK1
Blum, JE1
Hürlimann, A1
Bickel, M1
Le Doze, F1
Moulin, M1
Defer, GL1
Ohta, Y1
Kobayashi, T1
Ishiguro, I1
Neuschl, J1
Kohút, A1
Sieck, A1
Wenzl, H1
Graf, E1
Sandor, V1
Cuparencu, B2
Fernández de la Gandara, F1
Casas Carnicero, J1
Velasco Martin, A1
Otsuki, I1
Ishikawa, J1
Sakai, M1
Shimabara, K1
Momiyama, T1
Gayral, LF1
Möllmann, H2
Egbers, HJ2
Czitron, B1
Andrási, F1
Borsy, J1

Other Studies

17 other studies available for amitriptyline and Gastric Ulcer

ArticleYear
[Drugs news].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2017, Volume: 24, Issue:8

    Topics: Adolescent; Adult; Age Factors; Amitriptyline; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, N

2017
Evaluation of the anti-ulcerogenic activity of the antidepressants duloxetine, amitriptyline, fluoxetine and mirtazapine in different models of experimental gastric ulcer in rats.
    European journal of pharmacology, 2012, Sep-15, Volume: 691, Issue:1-3

    Topics: Amitriptyline; Animals; Anti-Ulcer Agents; Antidepressive Agents; Disease Models, Animal; Duloxetine

2012
Effect of amitriptyline on gastric ulceration.
    Fundamental & clinical pharmacology, 2002, Volume: 16, Issue:4

    Topics: Amitriptyline; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Aspirin; Col

2002
[On the influence of immobilization-triggered stomach ulcers of psychopharmaceuticals. Strengthening of the protective effect of amitryptyline with chlordiazepoxide].
    Medicina et pharmacologia experimentalis. International journal of experimental medicine, 1966, Volume: 15, Issue:6

    Topics: Amitriptyline; Animals; Chlordiazepoxide; Drug Synergism; Immobilization; Rats; Stomach Ulcer

1966
Antiulcer effects of nomifensine, a new antidepressant, on stress-induced ulcers in the rat.
    Arzneimittel-Forschung, 1980, Volume: 30, Issue:1

    Topics: Amitriptyline; Animals; Anti-Ulcer Agents; Gastric Mucosa; Humans; Immersion; Isoquinolines; Male; N

1980
Meige's syndrome in a patient treated with ranitidine.
    Movement disorders : official journal of the Movement Disorder Society, 1999, Volume: 14, Issue:1

    Topics: Aged; Amitriptyline; Anti-Ulcer Agents; Drug Therapy, Combination; Female; Humans; Meige Syndrome; R

1999
Role of endogenous serotonin and histamine in the pathogenesis of gastric mucosal lesions in unanaesthetised rats with a single treatment of compound 48/80, a mast cell degranulator.
    Pharmacological research, 1999, Volume: 39, Issue:4

    Topics: Adrenergic Uptake Inhibitors; Amitriptyline; Animals; Cell Degranulation; Cimetidine; Cyproheptadine

1999
[Effect of amitriptyline on the ulcerogenic action of phenylbutazone and reserpine with respect to calcium levels in the stomach wall and blood in rats of different ages (author's transl)].
    Bratislavske lekarske listy, 1979, Volume: 71, Issue:2

    Topics: Age Factors; Amitriptyline; Animals; Calcium; Gastric Mucosa; Phenylbutazone; Rats; Reserpine; Stoma

1979
The influence of amitriptylinoxide on experimental ulcers and gastric secretion in rats.
    Arzneimittel-Forschung, 1978, Volume: 28, Issue:10b

    Topics: Amitriptyline; Animals; Carbachol; Female; Gastric Mucosa; Humans; Male; Phenylbutazone; Rats; Restr

1978
Analysis of the mechanism of the protective activity of some sympathomimetic amines in experimental ulcers.
    Pharmacology, 1977, Volume: 15, Issue:3

    Topics: Amitriptyline; Amphetamine; Animals; Apomorphine; Butyrophenones; Catecholamines; Chlorpromazine; Co

1977
Effects of antidepressants on alcohol-induced gastric mucosal injury in rats.
    Methods and findings in experimental and clinical pharmacology, 1989, Volume: 11, Issue:10

    Topics: Amitriptyline; Animals; Antidepressive Agents; Chlorpheniramine; Cimetidine; Ethanol; Female; Gastri

1989
[General pharmacological effects of a psychotropic agent, doxepin hydrochloride].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1972, Volume: 68, Issue:6

    Topics: Amitriptyline; Anesthetics, Local; Animals; Anti-Inflammatory Agents; Antidepressive Agents; Body Te

1972
[Tranquillisers in the treatment of psychosomatic diseases].
    Munchener medizinische Wochenschrift (1950), 1972, Jun-23, Volume: 114, Issue:25

    Topics: Amitriptyline; Asthma; Benzazepines; Benzene Derivatives; Chlordiazepoxide; Colitis, Ulcerative; Dru

1972
[Comparative study on the influence of psychotropic agents on stress induced lesions of the gastric mucosa].
    Arzneimittel-Forschung, 1972, Volume: 22, Issue:4

    Topics: Administration, Oral; Amitriptyline; Animals; Chlordiazepoxide; Female; Fluphenazine; Gastric Mucosa

1972
A comparative investigation of the effects of specific psychotropic agents on immobilization-induced ulcer.
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1971, Volume: 4, Issue:3

    Topics: Amitriptyline; Animals; Central Nervous System; Chlordiazepoxide; Drug Synergism; Female; Fluphenazi

1971
A study of the effects of monoamine oxidase inhibitors on the experimental gastric and duodenal ulcers.
    Acta biologica et medica Germanica, 1971, Volume: 27, Issue:4

    Topics: Amitriptyline; Animals; Blood Glucose; Bretylium Compounds; Catecholamines; Cocaine; Duodenal Ulcer;

1971
[Investigation of gastric ulcer inhibiting and secreto-inhibitory actions of thymoleptics in rats].
    Acta pharmaceutica Hungarica, 1968, Volume: 38, Issue:2

    Topics: Amitriptyline; Animals; Antidepressive Agents; Desipramine; Gastric Juice; Imipramine; Nortriptyline

1968