amitriptyline has been researched along with Fatty Liver, Nonalcoholic in 2 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Since macrophages are vital players in nonalcoholic steatohepatitis (NASH) and atherosclerosis, we assessed the effect of ASMase inhibition on NASH and atherosclerosis cooperatively induced by high-PA-containing high-fat diet (HP-HFD) and LPS in LDL receptor-deficient (LDLR-/-) mice." | 5.56 | Amitriptyline inhibits nonalcoholic steatohepatitis and atherosclerosis induced by high-fat diet and LPS through modulation of sphingolipid metabolism. ( Huang, Y; Li, Y; Lopes-Virella, MF; Lu, Z; Lyons, TJ; Syn, WK; Wang, Z, 2020) |
| "Since macrophages are vital players in nonalcoholic steatohepatitis (NASH) and atherosclerosis, we assessed the effect of ASMase inhibition on NASH and atherosclerosis cooperatively induced by high-PA-containing high-fat diet (HP-HFD) and LPS in LDL receptor-deficient (LDLR-/-) mice." | 1.56 | Amitriptyline inhibits nonalcoholic steatohepatitis and atherosclerosis induced by high-fat diet and LPS through modulation of sphingolipid metabolism. ( Huang, Y; Li, Y; Lopes-Virella, MF; Lu, Z; Lyons, TJ; Syn, WK; Wang, Z, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lu, Z | 1 |
| Li, Y | 1 |
| Syn, WK | 1 |
| Wang, Z | 1 |
| Lopes-Virella, MF | 1 |
| Lyons, TJ | 1 |
| Huang, Y | 1 |
| Fucho, R | 1 |
| Martínez, L | 1 |
| Baulies, A | 1 |
| Torres, S | 1 |
| Tarrats, N | 1 |
| Fernandez, A | 1 |
| Ribas, V | 1 |
| Astudillo, AM | 1 |
| Balsinde, J | 1 |
| Garcia-Rovés, P | 1 |
| Elena, M | 1 |
| Bergheim, I | 1 |
| Lotersztajn, S | 1 |
| Trautwein, C | 1 |
| Appelqvist, H | 1 |
| Paton, AW | 1 |
| Paton, JC | 1 |
| Czaja, MJ | 1 |
| Kaplowitz, N | 1 |
| Fernandez-Checa, JC | 1 |
| García-Ruiz, C | 1 |
2 other studies available for amitriptyline and Fatty Liver, Nonalcoholic
| Article | Year |
|---|---|
Amitriptyline inhibits nonalcoholic steatohepatitis and atherosclerosis induced by high-fat diet and LPS through modulation of sphingolipid metabolism.
Topics: Amitriptyline; Aniline Compounds; Animals; Atherosclerosis; Benzylidene Compounds; Blood Glucose; Cy | 2020 |
ASMase regulates autophagy and lysosomal membrane permeabilization and its inhibition prevents early stage non-alcoholic steatohepatitis.
Topics: Amitriptyline; Animals; Autophagy; Ceramides; Cholesterol; Choline Deficiency; Diet, High-Fat; Disea | 2014 |