Page last updated: 2024-10-22

amitriptyline and Fabry Disease

amitriptyline has been researched along with Fabry Disease in 1 studies

Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.

Fabry Disease: An X-linked inherited metabolic disease caused by a deficiency of lysosomal ALPHA-GALACTOSIDASE A. It is characterized by intralysosomal accumulation of globotriaosylceramide and other GLYCOSPHINGOLIPIDS in blood vessels throughout the body leading to multi-system complications including renal, cardiac, cerebrovascular, and skin disorders.

Research Excerpts

ExcerptRelevanceReference
" A treatment plan was developed consisting of a low-dose morphine infusion with increasing dosage until pain was relieved."5.29Successful treatment of painful crises of Fabry disease with low dose morphine. ( Finley, GA; Gordon, KE; Ludman, MD, 1995)
" A treatment plan was developed consisting of a low-dose morphine infusion with increasing dosage until pain was relieved."1.29Successful treatment of painful crises of Fabry disease with low dose morphine. ( Finley, GA; Gordon, KE; Ludman, MD, 1995)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gordon, KE1
Ludman, MD1
Finley, GA1

Other Studies

1 other study available for amitriptyline and Fabry Disease

ArticleYear
Successful treatment of painful crises of Fabry disease with low dose morphine.
    Pediatric neurology, 1995, Volume: 12, Issue:3

    Topics: Amitriptyline; Child; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy,

1995