amitriptyline has been researched along with Epileptiform Neuralgia in 17 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| " There was moderate evidence for amitriptyline in patients with atypical facial pain." | 5.12 | Neuromodulators for Atypical Facial Pain and Neuralgias: A Systematic Review and Meta-Analysis. ( Ananth, A; Do, TM; Kattar, N; McCoul, ED; Unis, GD, 2021) |
| "There is low-quality evidence that the effect of tizanidine is not significantly different than that of carbamazepine in treating trigeminal neuralgia." | 4.89 | Non-antiepileptic drugs for trigeminal neuralgia. ( Chen, N; He, L; Yang, M; Zakrzewska, JM; Zhang, J; Zhou, M, 2013) |
| "This report presents two cases diagnosed with atypical odontalgia (AO) and successfully treated with amitriptyline as well as providing a review of the current literature on the subject." | 4.84 | Diagnosis and treatment of atypical odontalgia: a review of the literature and two case reports. ( Melis, M; Secci, S, 2007) |
| "The present study showed that the administration of multidrug regimens is a useful alternative in controlling trigeminal neuralgia in patients who are unable to tolerate higher doses of carbamazepine." | 3.78 | Use of single- and multi-drug regimens in the management of classic (idiopathic) trigeminal neuralgia: an 11-year experience at a single Sri Lankan institution. ( Ariyawardana, A; Pallegama, R; Ranasinghe, A; Sitheeque, M, 2012) |
| "Clomipramine was better tolerated." | 2.65 | Clomipramine and amitriptyline in the treatment of severe pain. ( Carasso, RL; Streifler, M; Yehuda, S, 1979) |
| "Tizanidine was investigated in two trials." | 2.43 | Non-antiepileptic drugs for trigeminal neuralgia. ( He, L; Wu, B; Zhou, M, 2006) |
| "The numbness was predominantly located in the innervated mental area and extended in some cases to the first and second trigeminal divisions." | 1.35 | Idiopathic trigeminal neuropathies: a presentation of 15 cases. ( Bagán, JV; García, B; Mora, E; Peñarrocha, M, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (35.29) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (23.53) | 29.6817 |
| 2010's | 6 (35.29) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Do, TM | 1 |
| Unis, GD | 1 |
| Kattar, N | 1 |
| Ananth, A | 1 |
| McCoul, ED | 1 |
| Collet, C | 1 |
| Haen, P | 1 |
| Laversanne, S | 1 |
| Brignol, L | 1 |
| Thiéry, G | 1 |
| Zhang, J | 1 |
| Yang, M | 2 |
| Zhou, M | 3 |
| He, L | 3 |
| Chen, N | 2 |
| Zakrzewska, JM | 2 |
| Haviv, Y | 1 |
| Zadik, Y | 1 |
| Sharav, Y | 1 |
| Benoliel, R | 1 |
| Peñarrocha, M | 2 |
| Mora, E | 1 |
| Bagán, JV | 1 |
| García, B | 1 |
| Lux, EA | 1 |
| Ariyawardana, A | 1 |
| Pallegama, R | 1 |
| Sitheeque, M | 1 |
| Ranasinghe, A | 1 |
| Wu, B | 1 |
| Felicio, AC | 1 |
| Godeiro, Cde O | 1 |
| Borges, V | 1 |
| Silva, SM | 1 |
| Ferraz, HB | 1 |
| Melis, M | 1 |
| Secci, S | 1 |
| Dalessio, DJ | 1 |
| Schaefer, MC | 1 |
| Reimann, I | 1 |
| Brune, GG | 1 |
| Wallace, JR | 1 |
| Carasso, RL | 1 |
| Yehuda, S | 1 |
| Streifler, M | 1 |
| Gayford, JJ | 1 |
| Redpath, TH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prospective, Cross Over Gabapentin vs Amitriptyline Study on Patients Suffering From Masticatory Muscle Pain[NCT02339662] | Phase 4 | 50 participants (Anticipated) | Interventional | 2015-02-28 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for amitriptyline and Epileptiform Neuralgia
| Article | Year |
|---|---|
Neuromodulators for Atypical Facial Pain and Neuralgias: A Systematic Review and Meta-Analysis.
Topics: Adult; Amitriptyline; Botulinum Toxins, Type A; Carbamazepine; Facial Nerve; Facial Pain; Female; Hu | 2021 |
Non-antiepileptic drugs for trigeminal neuralgia.
Topics: Amitriptyline; Analgesics; Anticonvulsants; Baclofen; Carbamazepine; Clomipramine; Clonidine; Humans | 2013 |
Non-antiepileptic drugs for trigeminal neuralgia.
Topics: Amitriptyline; Analgesics; Baclofen; Carbamazepine; Clomipramine; Clonidine; Humans; Pimozide; Propo | 2011 |
Non-antiepileptic drugs for trigeminal neuralgia.
Topics: Amitriptyline; Baclofen; Carbamazepine; Clomipramine; Clonidine; Humans; Pimozide; Propoxycaine; Ran | 2006 |
Diagnosis and treatment of atypical odontalgia: a review of the literature and two case reports.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Dental Pulp Diseases; Diagnosis, Differentia | 2007 |
The side-effects of carbamazepine.
Topics: Amitriptyline; Anemia, Aplastic; Carbamazepine; Dibenzazepines; Gastrointestinal Diseases; Humans; I | 1969 |
1 trial available for amitriptyline and Epileptiform Neuralgia
| Article | Year |
|---|---|
Clomipramine and amitriptyline in the treatment of severe pain.
Topics: Adult; Aged; Amitriptyline; Clomipramine; Female; Headache; Humans; Male; Middle Aged; Neuralgia; Pa | 1979 |
10 other studies available for amitriptyline and Epileptiform Neuralgia
| Article | Year |
|---|---|
Trigeminal neuralgia: a new therapy?
Topics: Adipose Tissue; Amitriptyline; Cosmetic Techniques; Demyelinating Diseases; Face; Female; Humans; Li | 2013 |
Painful traumatic trigeminal neuropathy: an open study on the pharmacotherapeutic response to stepped treatment.
Topics: Amines; Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Baclofen; Carbamazepine; Clinical Proto | 2014 |
Idiopathic trigeminal neuropathies: a presentation of 15 cases.
Topics: Adult; Aged; Amitriptyline; Analgesics, Non-Narcotic; Cohort Studies; Facial Pain; Female; Humans; H | 2009 |
Case report: successful treatment of a patient with trigeminal neuropathy using ziconotide.
Topics: Amitriptyline; Analgesics; Antidepressive Agents, Tricyclic; Azabicyclo Compounds; Calcium Channel B | 2010 |
Use of single- and multi-drug regimens in the management of classic (idiopathic) trigeminal neuralgia: an 11-year experience at a single Sri Lankan institution.
Topics: Adult; Aged; Aged, 80 and over; Amines; Amitriptyline; Analgesics; Carbamazepine; Cyclohexanecarboxy | 2012 |
Bilateral hemifacial spasm and trigeminal neuralgia: a unique form of painful tic convulsif.
Topics: Aged; Amines; Amitriptyline; Analgesics; Arachnoid Cysts; Botulinum Toxins, Type A; Cyclohexanecarbo | 2007 |
Chronic pain syndromes and disordered cortical inhibition: effects of tricyclic compounds.
Topics: Amitriptyline; Animals; Anticonvulsants; Cerebral Cortex; Humans; Imipramine; Mice; Pain; Paresthesi | 1967 |
A regimen of tricyclic compounds and carbamazepine for treating trigeminal neuralgia pain.
Topics: Amitriptyline; Carbamazepine; Chlordiazepoxide; Drug Combinations; Humans; Pain; Trigeminal Neuralgi | 1981 |
[Short-term and long-term effects of psychotropic drugs in the treatment of trigeminal neuralgia (author's transl)].
Topics: Amitriptyline; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Benperidol; Carbamazepi | 1979 |
Trigeminal neuropathy.
Topics: Adult; Amitriptyline; Drug Combinations; Female; Humans; Male; Mandible; Middle Aged; Perphenazine; | 1977 |