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amitriptyline and Epilepsies, Partial

amitriptyline has been researched along with Epilepsies, Partial in 3 studies

Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.

Epilepsies, Partial: Conditions characterized by recurrent paroxysmal neuronal discharges which arise from a focal region of the brain. Partial seizures are divided into simple and complex, depending on whether consciousness is unaltered (simple partial seizure) or disturbed (complex partial seizure). Both types may feature a wide variety of motor, sensory, and autonomic symptoms. Partial seizures may be classified by associated clinical features or anatomic location of the seizure focus. A secondary generalized seizure refers to a partial seizure that spreads to involve the brain diffusely. (From Adams et al., Principles of Neurology, 6th ed, pp317)

Research Excerpts

ExcerptRelevanceReference
"(1) The first-line treatment for partial epilepsy is carbamazepine monotherapy; gabapentin monotherapy is an alternative, given its lower risk of drug-drug interactions."1.33Pregabalin: new drug. Very similar to gabapentin. ( , 2005)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vol'f, MSh1
Förstl, H1
Zagorski, A1
Pohlmann-Eden, B1

Other Studies

3 other studies available for amitriptyline and Epilepsies, Partial

ArticleYear
Pregabalin: new drug. Very similar to gabapentin.
    Prescrire international, 2005, Volume: 14, Issue:80

    Topics: Amines; Amitriptyline; Anticonvulsants; Clinical Trials as Topic; Cost-Benefit Analysis; Cyclohexane

2005
[Psychotropic drugs in the clinical picture of epilepsy (review of the literature)].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1975, Volume: 75, Issue:3

    Topics: Amitriptyline; Animals; Anti-Anxiety Agents; Anticonvulsants; Antipsychotic Agents; Carbamazepine; C

1975
Somatosensory evoked potentials as indicators of altered cerebral excitability during psychotropic drug treatment.
    Biological psychiatry, 1991, Feb-15, Volume: 29, Issue:4

    Topics: Aged; Amitriptyline; Antidepressive Agents; Arousal; Depressive Disorder; Electroencephalography; Ep

1991