amitriptyline has been researched along with Epilepsies, Partial in 3 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Epilepsies, Partial: Conditions characterized by recurrent paroxysmal neuronal discharges which arise from a focal region of the brain. Partial seizures are divided into simple and complex, depending on whether consciousness is unaltered (simple partial seizure) or disturbed (complex partial seizure). Both types may feature a wide variety of motor, sensory, and autonomic symptoms. Partial seizures may be classified by associated clinical features or anatomic location of the seizure focus. A secondary generalized seizure refers to a partial seizure that spreads to involve the brain diffusely. (From Adams et al., Principles of Neurology, 6th ed, pp317)
Excerpt | Relevance | Reference |
---|---|---|
"(1) The first-line treatment for partial epilepsy is carbamazepine monotherapy; gabapentin monotherapy is an alternative, given its lower risk of drug-drug interactions." | 1.33 | Pregabalin: new drug. Very similar to gabapentin. ( , 2005) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (33.33) | 18.7374 |
1990's | 1 (33.33) | 18.2507 |
2000's | 1 (33.33) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Vol'f, MSh | 1 |
Förstl, H | 1 |
Zagorski, A | 1 |
Pohlmann-Eden, B | 1 |
3 other studies available for amitriptyline and Epilepsies, Partial
Article | Year |
---|---|
Pregabalin: new drug. Very similar to gabapentin.
Topics: Amines; Amitriptyline; Anticonvulsants; Clinical Trials as Topic; Cost-Benefit Analysis; Cyclohexane | 2005 |
[Psychotropic drugs in the clinical picture of epilepsy (review of the literature)].
Topics: Amitriptyline; Animals; Anti-Anxiety Agents; Anticonvulsants; Antipsychotic Agents; Carbamazepine; C | 1975 |
Somatosensory evoked potentials as indicators of altered cerebral excitability during psychotropic drug treatment.
Topics: Aged; Amitriptyline; Antidepressive Agents; Arousal; Depressive Disorder; Electroencephalography; Ep | 1991 |