amitriptyline and Enuresis studies

Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.

Enuresis: Involuntary discharge of URINE after expected age of completed development of urinary control. This can happen during the daytime (DIURNAL ENURESIS) while one is awake or during sleep (NOCTURNAL ENURESIS). Enuresis can be in children or in adults (as persistent primary enuresis and secondary adult-onset enuresis).

Research Excerpts

Excerpt	Relevance	Reference
"Forty-five children aged 6-14 years with primary nocturnal enuresis were randomised to determine whether desmopressin is more effective than amitriptyline and whether the combination of amitriptyline/desmopressin is more effective than amitriptyline or desmopressin alone."	9.08	A comparison of amitriptyline, vasopressin and amitriptyline with vasopressin in nocturnal enuresis. ( Burke, JR; Chan, A; Mizusawa, Y; Webb, KL, 1995)
"Forty-five children aged 6-14 years with primary nocturnal enuresis were randomised to determine whether desmopressin is more effective than amitriptyline and whether the combination of amitriptyline/desmopressin is more effective than amitriptyline or desmopressin alone."	5.08	A comparison of amitriptyline, vasopressin and amitriptyline with vasopressin in nocturnal enuresis. ( Burke, JR; Chan, A; Mizusawa, Y; Webb, KL, 1995)
" Cardiac arrhythmias induced in children by amitriptyline and imipramine are prominent and dangerous."	3.65	Amitriptyline and imipramine poisoning in children. ( Goel, KM; Shanks, RA, 1974)
"Nocturnal enuresis is a common childhood disorder."	1.31	Combined pharmacotherapy for nocturnal enuresis. ( Fujinaga, S; Kaneko, K; Ohtomo, Y; Shimizu, T; Yamashiro, Y, 2001)

Timeframe	Studies, this research(%)	All Research%
pre-1990	37 (90.24)	18.7374
1990's	3 (7.32)	18.2507
2000's	1 (2.44)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors	Studies
KUROKAWA, K	1
OTAGURO, W	1
OTTO, U	1
Drew, LR	1
Mishra, PC	1
Agarwal, VK	1
Rahman, H	1
Mehrotra, SN	1
Liu, L	1
Srivastava, JR	1
Singh, SB	1
Burke, JR	1
Mizusawa, Y	1
Chan, A	1
Webb, KL	1
Robson, WL	1
Nørgaard, JP	1
Gruzman, AV	1
Kaneko, K	1
Fujinaga, S	1
Ohtomo, Y	1
Shimizu, T	1
Yamashiro, Y	2
Höfler, G	1
Kolvin, I	1
Ballin, JC	1
Yamanishi, T	1
Igarashi, T	1
Murakami, S	1
Murayama, N	1
Kamura, K	1
Yasuda, K	1
Shimazaki, J	1
Endo, H	1
Goh, CW	1
Parkin, JM	1
Fraser, MS	1
Gill, D	1
Wheatley, D	1
Forsythe, WI	1
Merrett, JD	1
Redmond, A	1
Kelly, MG	1
Bain, DJ	1
Ravn, J	1
Goel, KM	1
Shanks, RA	1
Meadow, R	1
Postlethwaite, RJ	1
Price, DA	1
Crisp, AH	1
Hafner, J	1
Lines, DR	1
Shaffer, D	1
Costello, AJ	1
Hill, ID	1
Shah, LP	1
D'Hollander, L	1
Vaneck, L	1
Appel, P	1
Eckel, K	1
Harrer, G	1
Niikoli, V	1
Sallou, C	1
Rydzyński, Z	1
Weychert, A	1
Hershkorn, H	1
Porot, M	1
Girard, J	1
Nievoll, A	1
Franczak, W	1
Ayd, FJ	1

Article	Year
Therapeutic trial of amitryptiline in the treatment of nocturnal enuresis--a controlled study. Indian pediatrics, 1980, Volume: 17, Issue:3 Topics: Adolescent; Amitriptyline; Child; Child, Preschool; Clinical Trials as Topic; Enuresis; Follow-Up St	1980
Evaluation of various methods in treatment of enuresis. Indian pediatrics, 1980, Volume: 17, Issue:6 Topics: Amitriptyline; Child; Child, Preschool; Enuresis; Evaluation Studies as Topic; Follow-Up Studies; Hu	1980
A comparison of amitriptyline, vasopressin and amitriptyline with vasopressin in nocturnal enuresis. Pediatric nephrology (Berlin, Germany), 1995, Volume: 9, Issue:4 Topics: Adolescent; Amitriptyline; Antidepressive Agents, Tricyclic; Child; Double-Blind Method; Drug Therap	1995
[The treatment of nocturnal enuresis in children]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 1997, Volume: 97, Issue:8 Topics: Adolescent; Amitriptyline; Antidepressive Agents, Tricyclic; Child; Child, Preschool; Drug Evaluatio	1997
Evaluation of psychotropic drugs in general practice. Proceedings of the Royal Society of Medicine, 1972, Volume: 65, Issue:4 Topics: Amitriptyline; Antidepressive Agents; Anxiety; Chlordiazepoxide; Clinical Trials as Topic; Depressio	1972
Enuresis and psychoactive drugs. The British journal of clinical practice, 1972, Volume: 26, Issue:3 Topics: Adolescent; Amitriptyline; Child; Child, Preschool; Chlordiazepoxide; Clinical Trials as Topic; Dibe	1972
Trial of sustained release amitriptyline on enuresis. Journal of the Irish Medical Association, 1974, Jun-29, Volume: 67, Issue:12 Topics: Amitriptyline; Clinical Trials as Topic; Delayed-Action Preparations; Drug Evaluation; Enuresis; Hum	1974
A double-blind trial of amitriptyline in enuretic children. The Medical journal of Australia, 1968, Aug-17, Volume: 2, Issue:7 Topics: Adolescent; Amitriptyline; Child; Child, Preschool; Clinical Trials as Topic; Enuresis; Humans; Plac	1968
Control of enuresis with imipramine. Archives of disease in childhood, 1968, Volume: 43, Issue:232 Topics: Amitriptyline; Child; Child Behavior Disorders; Clinical Trials as Topic; Enuresis; Female; Follow-U	1968
Amitryptiline in the treatment of enuresis. Indian pediatrics, 1971, Volume: 8, Issue:11 Topics: Adolescent; Amitriptyline; Child; Child, Preschool; Clinical Trials as Topic; Enuresis; Female; Huma	1971
[Treatment of enuresis by imipramine and amitriptyline in retarded children]. Acta neurologica et psychiatrica Belgica, 1967, Volume: 67, Issue:5 Topics: Adolescent; Amitriptyline; Child; Child, Preschool; Clinical Trials as Topic; Enuresis; Humans; Imip	1967

Article	Year
[Triptanol(amitriptyline hydrochloride) therapy for nocturnal enuresis]. [Chiryo] [Therapy], 1963, Volume: 45 Topics: Amitriptyline; Antidepressive Agents; Enuresis; Humans; Nocturnal Enuresis	1963
[COMPARATIVE STUDY OF PREPARYL, TOFRANIL AND TRYPTIZOL IN ENURESIS NOCTURNA WITH SEVERE DEVELOPMENTAL DISORDERS IN CHILDREN AND YOUNG PEOPLE]. Svenska lakartidningen, 1964, Dec-09, Volume: 61 Topics: Adolescent; Amitriptyline; Amobarbital; Child; Child Behavior Disorders; Drug Combinations; Drug The	1964
Drug control of incontinence in adult mental defectives. The Medical journal of Australia, 1967, Jul-29, Volume: 2, Issue:5 Topics: Amitriptyline; Defecation; Encopresis; Enuresis; Humans; Imipramine; Intellectual Disability; Male	1967
Amitriptyline versus vasopressin in the treatment of nocturnal enuresis. Pediatric nephrology (Berlin, Germany), 1996, Volume: 10, Issue:3 Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Child; Deamino Arginine Vasopressin; Enuresis; Huma	1996
Combined pharmacotherapy for nocturnal enuresis. Pediatric nephrology (Berlin, Germany), 2001, Volume: 16, Issue:8 Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Benzilates; Child; Cholinergic Antagonists; Drug Th	2001
[Ambulatory treatment of enuresis diurna and nocturna with amitriptylin]. Wiener medizinische Wochenschrift (1946), 1978, Volume: 128, Issue:21 Topics: Adolescent; Ambulatory Care; Amitriptyline; Child; Enuresis; Female; Humans; Male	1978
Editorial: Toxicity of tricyclic antidepressants. JAMA, 1975, Mar-31, Volume: 231, Issue:13 Topics: Acute Disease; Amitriptyline; Antidepressive Agents; Depression; Drug Utilization; Electrocardiograp	1975
[A comparative study of the effects of drug therapy and bladder training therapy]. Hinyokika kiyo. Acta urologica Japonica, 1988, Volume: 34, Issue:1 Topics: Adolescent; Adult; Amitriptyline; Child; Child, Preschool; Chlordiazepoxide; Diazepam; Enuresis; Fem	1988
Enuresis: outcome of treatment. Singapore medical journal, 1986, Volume: 27, Issue:6 Topics: Adolescent; Amitriptyline; Child; Enuresis; Female; Humans; Imipramine; Male; Retrospective Studies	1986
Poisoning as a complication of enuresis. Developmental medicine and child neurology, 1972, Volume: 14, Issue:6 Topics: Amitriptyline; Antidepressive Agents; Child, Preschool; Enuresis; Humans; Imipramine; Ipecac; Nortri	1972
Letter: Breast cancer. Irish medical journal, 1974, Aug-31, Volume: 67, Issue:16 Topics: Adolescent; Amitriptyline; Child; Enuresis; Humans	1974
A criticism of the use of tricyclic antidepressant drugs in the treatment of childhood enuresis. The Journal of the Royal College of General Practitioners, 1973, Volume: 23, Issue:128 Topics: Adolescent; Amitriptyline; Child; Child, Preschool; Enuresis; Family Practice; Humans; Imipramine; I	1973
[Enuresis nocturna and imipramine]. Ugeskrift for laeger, 1973, Nov-26, Volume: 135, Issue:48 Topics: Amitriptyline; Enuresis; Humans; Imipramine	1973
Amitriptyline and imipramine poisoning in children. British medical journal, 1974, Feb-16, Volume: 1, Issue:5902 Topics: Amitriptyline; Arrhythmias, Cardiac; Child, Preschool; Depression; Enuresis; Female; Humans; Imipram	1974
Letter: Amitriptyline and imipramine poisoning in children. British medical journal, 1974, Apr-20, Volume: 2, Issue:5911 Topics: Amitriptyline; Antidotes; Child; Enuresis; Humans; Imipramine; Phenytoin; Physostigmine	1974
Drugs for bed-wetting. Archives of disease in childhood, 1974, Volume: 49, Issue:4 Topics: Amitriptyline; Child; Enuresis; Humans; Imipramine; Time Factors	1974
Letter: Amitriptyline and imipramine poisoning in children. British medical journal, 1974, Jun-01, Volume: 2, Issue:5917 Topics: Amitriptyline; Child; Enuresis; Heart Diseases; Humans; Imipramine; Phenytoin; Poisoning	1974
Nocturnal activity and enuresis. A study of a 35 year old male. Journal of neurology, neurosurgery, and psychiatry, 1974, Volume: 37, Issue:5 Topics: Adult; Affective Symptoms; Amitriptyline; Barbiturates; Enuresis; Humans; Male; Movement; Psychother	1974
Wetting and soiling. British medical journal, 1972, Jul-29, Volume: 3, Issue:5821 Topics: Amitriptyline; Child; Enuresis; Fecal Incontinence; Humans; Imipramine	1972
[Changes in tonus of the bladder and its sphincter under thymoleptic treatment. Cystomanometric measurements in man]. International pharmacopsychiatry, 1971, Volume: 6, Issue:1 Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Carbachol; Desipramine; Dibenzazepines; Enuresis;	1971
[Enuresis in practice]. Medicinski pregled, 1969, Volume: 22, Issue:9 Topics: Amitriptyline; Child; Child, Preschool; Enuresis; Humans; Imipramine; Infant	1969
[Effect of amitryptyline drops, in ambulatory therapy, on behavior and character disorders in children and adolescents]. Revue de neuropsychiatrie infantile et d'hygiene mentale de l'enfance, 1969, Volume: 17, Issue:12 Topics: Adolescent; Aggression; Amitriptyline; Character; Child; Child Behavior Disorders; Child, Preschool;	1969
Value of amitriptylin--Spofa in the psychiatric out- and in-patient practice. Activitas nervosa superior, 1970, Jan-12, Volume: 12, Issue:1 Topics: Adolescent; Adult; Aged; Amitriptyline; Child; Child, Preschool; Depression; Enuresis; Female; Human	1970
Enuresis and bell alarms. British medical journal, 1970, Mar-21, Volume: 1, Issue:5698 Topics: Amitriptyline; Child; Child, Preschool; Enuresis; Humans; Imipramine; Male	1970
[Use of amitriptyline in syrup form in the treatment of enuresis amitriptyline in children]. Annales medico-psychologiques, 1970, Volume: 128, Issue:5 Topics: Amitriptyline; Child; Child, Preschool; Enuresis; Female; Humans; Male; Pharmaceutical Vehicles	1970
[Therapeutic experiences with oxazepam--a derivative of the benzodiazepine series--in child and adolescent psychiatry]. Wiener klinische Wochenschrift, 1971, Apr-09, Volume: 83, Issue:14 Topics: Adolescent; Adolescent Psychiatry; Adult; Aggression; Amitriptyline; Anticonvulsants; Brain Damage,	1971
Tricyclic antidepressants. British medical journal, 1968, Apr-13, Volume: 2, Issue:5597 Topics: Amitriptyline; Antidepressive Agents; Desipramine; Dibenzazepines; Enuresis; Humans; Imipramine; Nor	1968
[Treatment of enuresis in children with melitracene]. Polski tygodnik lekarski (Warsaw, Poland : 1960), 1969, Jan-27, Volume: 24, Issue:4 Topics: Adolescent; Amitriptyline; Anthracenes; Antidepressive Agents; Child; Enuresis; Humans; Imipramine;	1969
Amitriptyline: reappraisal after six years experience. Diseases of the nervous system, 1965, Volume: 26, Issue:11 Topics: Amitriptyline; Depression; Enuresis; Humans	1965

amitriptyline and Enuresis

Research Excerpts

Research

Studies (41)

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