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amitriptyline and Endocarditis

amitriptyline has been researched along with Endocarditis in 1 studies

Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.

Endocarditis: Inflammation of the inner lining of the heart (ENDOCARDIUM), the continuous membrane lining the four chambers and HEART VALVES. It is often caused by microorganisms including bacteria, viruses, fungi, and rickettsiae. Left untreated, endocarditis can damage heart valves and become life-threatening.

Research Excerpts

ExcerptRelevanceReference
"Three patients with documented or suspected amitriptyline poisoning developed a uniform clinical picture with progressive respiratory insufficiency, thrombocytopenia and evidence of embolization."7.65Respiratory distress syndrome and thrombotic, non-bacterial endocarditis after amitriptyline overdose. ( Flodmark, O; Gustafsson, B; Lindström, FD, 1977)
"Three patients with documented or suspected amitriptyline poisoning developed a uniform clinical picture with progressive respiratory insufficiency, thrombocytopenia and evidence of embolization."3.65Respiratory distress syndrome and thrombotic, non-bacterial endocarditis after amitriptyline overdose. ( Flodmark, O; Gustafsson, B; Lindström, FD, 1977)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lindström, FD1
Flodmark, O1
Gustafsson, B1

Other Studies

1 other study available for amitriptyline and Endocarditis

ArticleYear
Respiratory distress syndrome and thrombotic, non-bacterial endocarditis after amitriptyline overdose.
    Acta medica Scandinavica, 1977, Volume: 202, Issue:3

    Topics: Adolescent; Adult; Amitriptyline; Endocarditis; Female; Humans; Lung; Middle Aged; Myocardium; Respi

1977