amitriptyline has been researched along with Electron Transport Chain Deficiencies, Mitochondrial in 1 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amitriptyline is a commonly prescribed tricyclic antidepressant, which has been shown to impair mitochondrial function and increase oxidative stress in a variety of in vitro assays." | 1.38 | Oral treatment with amitriptyline induces coenzyme Q deficiency and oxidative stress in psychiatric patients. ( Alcocer-Gómez, E; Carmona-López, MI; Casas-Barquero, N; Cordero, MD; de Miguel, M; Garrido-Maraver, J; Moreno-Fernández, AM; Sánchez-Alcázar, JA, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moreno-Fernández, AM | 1 |
| Cordero, MD | 1 |
| Garrido-Maraver, J | 1 |
| Alcocer-Gómez, E | 1 |
| Casas-Barquero, N | 1 |
| Carmona-López, MI | 1 |
| Sánchez-Alcázar, JA | 1 |
| de Miguel, M | 1 |
1 other study available for amitriptyline and Electron Transport Chain Deficiencies, Mitochondrial
| Article | Year |
|---|---|
Oral treatment with amitriptyline induces coenzyme Q deficiency and oxidative stress in psychiatric patients.
Topics: Adenosine Triphosphate; Administration, Oral; Adult; Amitriptyline; Antidepressive Agents, Tricyclic | 2012 |