amitriptyline has been researched along with Dystonia in 3 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Dystonia: An attitude or posture due to the co-contraction of agonists and antagonist muscles in one region of the body. It most often affects the large axial muscles of the trunk and limb girdles. Conditions which feature persistent or recurrent episodes of dystonia as a primary manifestation of disease are referred to as DYSTONIC DISORDERS. (Adams et al., Principles of Neurology, 6th ed, p77)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Haloperidol was implicated in 47 patients (37%), followed by amitriptyline/perphenazine in 30%, thioridazine in 27%, and chlorpromazine in 20%." | 1.28 | Neurologic approach to drug-induced movement disorders: a study of 125 patients. ( Jankovic, J; Miller, LG, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Finder, E | 1 |
| Lin, KM | 1 |
| Ananth, J | 1 |
| Miller, LG | 1 |
| Jankovic, J | 1 |
| Lee, HK | 1 |
3 other studies available for amitriptyline and Dystonia
| Article | Year |
|---|---|
Dystonic reaction to amitriptyline.
Topics: Acute Disease; Adult; Amitriptyline; Depressive Disorder; Dystonia; Humans; Male | 1982 |
Neurologic approach to drug-induced movement disorders: a study of 125 patients.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Amitriptyline; Antipsychotic Agents; Chorea | 1990 |
Dystonic reactions to amitriptyline and doxepin.
Topics: Adult; Amitriptyline; Basal Ganglia Diseases; Depressive Disorder; Doxepin; Dystonia; Female; Humans | 1988 |