amitriptyline has been researched along with Diabetic Foot in 2 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Diabetic Foot: Common foot problems in persons with DIABETES MELLITUS, caused by any combination of factors such as DIABETIC NEUROPATHIES; PERIPHERAL VASCULAR DISEASES; and INFECTION. With the loss of sensation and poor circulation, injuries and infections often lead to severe foot ulceration, GANGRENE and AMPUTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The pathogenesis of diabetic neuropathies is not clear, but possibly involves a complex of metabolic factors inducing nerve ischaemia." | 2.43 | [Diabetic neuropathy--a clinical review]. ( Berg, TJ; Nøkleby, K, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nøkleby, K | 1 |
| Berg, TJ | 1 |
| Kerstein, MD | 1 |
| Polsky, S | 1 |
1 review available for amitriptyline and Diabetic Foot
| Article | Year |
|---|---|
[Diabetic neuropathy--a clinical review].
Topics: Amitriptyline; Analgesics, Non-Narcotic; Diabetic Foot; Diabetic Neuropathies; Diagnosis, Differenti | 2005 |
1 other study available for amitriptyline and Diabetic Foot
| Article | Year |
|---|---|
Treating wounds associated with decreased sensibility.
Topics: Amitriptyline; Capsaicin; Diabetic Foot; Diabetic Neuropathies; Humans; Shoes; Skin Care | 1995 |