amitriptyline has been researched along with Dementia in 17 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Dementia: An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acute anticholinergic delirium has been reported to occur following ingestion of antidepressants, neuroleptics and antiparkinsonian drugs in toxic and therapeutic doses." | 1.27 | Chronic central anticholinergic toxicity in manic depressive illness mimicking dementia. ( Banno, V; Jones, BD; Moreau, A, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (88.24) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (11.76) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wettstein, A | 1 |
| Fritz, Ch | 1 |
| Pollard, AJ | 1 |
| Prendergast, M | 1 |
| Bourgeois, M | 1 |
| Werner, V | 1 |
| Diehl, LW | 1 |
| Reding, MJ | 1 |
| Young, R | 1 |
| DiPonte, P | 1 |
| Busch, KT | 1 |
| Schulz, H | 1 |
| Davies, G | 2 |
| Hamilton, S | 2 |
| Hendrickson, E | 1 |
| Levy, R | 2 |
| Post, F | 3 |
| Hendrickson, DE | 1 |
| Reid, RW | 1 |
| Youngs, DD | 1 |
| Shrimankar, J | 1 |
| Soni, SD | 1 |
| Sampath, G | 1 |
| Moreau, A | 1 |
| Jones, BD | 1 |
| Banno, V | 1 |
| Jenike, MA | 1 |
| Wamboldt, MZ | 1 |
| Kalin, NH | 1 |
| Weiler, SJ | 1 |
| Gol'dovskaia, IL | 1 |
| Asnes, DP | 1 |
| Hader, M | 1 |
| Madonick, JJ | 1 |
1 review available for amitriptyline and Dementia
| Article | Year |
|---|---|
[The state of psychopharmacotherapy in geriatrics 2].
Topics: Actihaemyl; Aged; Amitriptyline; Bencyclane; Cerebrovascular Circulation; Clorazepate Dipotassium; D | 1980 |
2 trials available for amitriptyline and Dementia
| Article | Year |
|---|---|
Amitriptyline in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Amitriptyline; Dementia; Female; Humans; Male; Psychiatric Status Rating Sc | 1983 |
The effect of cyclandelate in depressed and demented patients: a controlled study in psychogeriatric patients.
Topics: Aged; Amitriptyline; Clinical Trials as Topic; Cyclandelate; Dementia; Depression; Drug Evaluation; | 1977 |
14 other studies available for amitriptyline and Dementia
| Article | Year |
|---|---|
[Iatrogenic dementia?].
Topics: Aged; Aged, 80 and over; Amitriptyline; Antidepressive Agents, Tricyclic; Antiparkinson Agents; Bipe | 2003 |
Depressive pseudodementia in a child with autism.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Autistic Disorder; Child; Dementia; Depressive Diso | 2004 |
[Study of an antidepressive agent in psychiatry: Mutabon F].
Topics: Adjustment Disorders; Adolescent; Adult; Aged; Amitriptyline; Anxiety Disorders; Bipolar Disorder; D | 1967 |
[The acute psychiatric emergency].
Topics: Acute Disease; Aged; Alcoholism; Amitriptyline; Brain Ischemia; Cognition Disorders; Consciousness D | 1981 |
Psychological test performance and sedation thresholds of elderly dements, depressives and depressives with incipient brain change.
Topics: Aged; Amitriptyline; Dementia; Depression; Dose-Response Relationship, Drug; Humans; Middle Aged; Ps | 1978 |
Second thoughts on dementia. Evaluation and management of patients with mild dementia.
Topics: Aged; Amitriptyline; Anxiety; Chlordiazepoxide; Dementia; Depression; Diazepam; Female; Humans; Male | 1975 |
Dexamethasone suppression test and response to antidepressant therapy in psychogeriatric patients.
Topics: Aged; Amitriptyline; Dementia; Depressive Disorder; Dexamethasone; Female; Humans; Hydrocortisone; M | 1988 |
Chronic central anticholinergic toxicity in manic depressive illness mimicking dementia.
Topics: Aged; Amitriptyline; Benztropine; Bipolar Disorder; Central Nervous System Diseases; Dementia; Diagn | 1986 |
Use of MAOIs for demented depressed patients.
Topics: Aged; Alzheimer Disease; Amitriptyline; Dementia; Depressive Disorder; Humans; Male; Monoamine Oxida | 1986 |
Consistent reversal of abnormal DSTs after different antidepressant therapies in a patient with dementia.
Topics: Amitriptyline; Antidepressive Agents; Dementia; Depressive Disorder; Dexamethasone; Humans; Hydrocor | 1985 |
[The possibilities and limitations of psychotropic drug therapy for patients with glaucoma].
Topics: Aged; Alcoholism; Amitriptyline; Antidepressive Agents; Bipolar Disorder; Chronic Disease; Dementia; | 1974 |
Psychopharmacology in the aged. Use of major psychotropic medications in treatment of the elderly: case examples.
Topics: Adjustment Disorders; Aged; Alzheimer Disease; Amitriptyline; Benztropine; Bipolar Disorder; Cataton | 1974 |
Management of senile psychiatric disorders.
Topics: Adjustment Disorders; Affective Symptoms; Aged; Alcoholism; Amitriptyline; Dementia; Depressive Diso | 1968 |
Experiences with amitriptyline in elderly patients.
Topics: Aged; Amitriptyline; Brain Damage, Chronic; Dementia; Depression; Depressive Disorder, Major; Female | 1966 |